Biomedical Technology Quiz I

Which type of research method may be conducted on either animals, humans, computer models, or tissue cultures?
Clinical research
In vitro research
Applied research
Basic Research
Which level of biomedical research is considered a foundation or "building block" level?
Basic research
Applied research
Clinical research
Phase I
What research method is the best known surrogate for humans in the laboratory?
Computer Models
Mathmatical models
Non human animal models
In vitro models
Which type of study is the human equivalent of animal testing and is administered by providing or withholding a substance to determine its toxic or beneficial effects?
Experimental epidemiology
Descriptive epidemiology
Observational epidemiology
Distributive epidemiology
A major disadvantage of epidemiological studies is that:
They identify patterns in diseases that may be traced to causative factors
Ethical considerations may limit their usefulness
Considerable human exposure can take place before a toxic effect is detectable
It is difficult to generate sufficiently reliable data
Julio is a researcher and has been assigned to collect statistical data on the Zika virus. What level of research is he working on if his findings will be used to develop a vaccine or new treatment?
Basic research
Applied research
Clinical research
Phase I
During which phase of clinical trials is the safety and effectiveness of a medication tested on the greatest number and variety of participants?
Phase I
Phase II
Phase III
Phase IV
Research experiments that use animals as models should be set up using the three Rs, which are:
Restrict, reduce, and reconfigure the use of animals
Reconstruct, recycle, and reconfigure the use of animals.
Replace, reduce, and refine the use of animals
Reuse, redistribute, and redefine the use of animals
Which phase of clinical research is used to determine a drug's interaction with the human system, involves a small number of healthy volunteers, and usually takes around one year to finish?
Phase I
Phase II
Phase III
Phase IV
The use of mice in biomedical research most frequently occurs at which level?
Basic research
Applied research
Clinical research
Phase I research
Which type of epidemiological study is greatly limited by ethical and legal considerations?
Experimental
Observational
Geographical
Discriptive
Which group is often given a placebo or inactive substance when a new medication is tested in biomedical research?
Experimental
Control
Homogenus
Descriptive
Descriptive epidemiological studies identify:
Direct cause and effect
Correlations
Selection bias
Incidence numbers and distribution spread
What stage of clinical trials involves extensive testing, using around 1,000–3,000 subjects, with the overall purpose of determining a drug's efficacy and adverse reactions?
Phase I
Phase II
Phase III
Phase IV
Congress passed the Clinical Laboratory Improvement Amendments in 1988 to ensure the accuracy of diagnostic testing. Under this law, the federal government regulates many aspects of laboratory operation, including:
Making sure labels with at least two patient identifiers, such as name and date of birth
The training employees receive and the types and quality of instruments used to analyze samples
Making sure labels with at least two patient identifiers, such as name and record number
The training employees receive and use at least two patient identifiers, such as name and date of birth
An experimental medication is being tested on research mice. To obtain the most accurate results, the test should include an experimental group and a/an:
Epidemic group
Phase I group
Descriptive group
Control group
Which type of research involves human subjects and is conducted after other forms of research have already taken place?
Basic research
Applied research
Clinical research
Toxicity research
Which type of research is directed towards specific objectives and is conducted using animals and other nonanimal models such as computers and tissue cultures?
Basic research
Applied research
Clinical research
Descriptive Research
Which term best describes the study of disease incidence and its distribution in a population?
Comparisons
Descriptive
Epidemiology
Observational
Adult stem cells are to be harvested and transplanted into a patient. Where would these cells most likely be found?
In an embryo
In muscle tissue
In human bone marrow
In a clone
Scientists are currently conducting studies in vitro. Where are these studies most likely taking place?
In a petri dish or test tube
In a living organism
In an animal cage
In a computer database
Chemical, mechanical, and computer simulations are effective research methods but cannot:
Replace building blocks
Replace laboratory testing on animals
Reduce the number of scientists needed
Reduce the total time spent on research
What area of science studies biological life processes and the causes for disease?
Biomedical research
Physical research
Scientific research
Lifestyle research
During biomedical research using animals, a control group was given a placebo. This group will most likely have what type of response?
A positive repsonse
A negative response
No response
A side effect
Epidemiology studies may be divided up into three general types:
Experimental, descriptive, and observational
Experimental, comparison, and case-controlled
Observational, descriptive, and case-controlled
Observational, retrospective, and experimental
Stan is working with a type of research study with some limitations. This study cannot respond to other functions within a living organism or whole body systems. This type of research can be identified as:
Basic research
Clinical research
Phase I
In vitro
The Clinical Laboratory Improvement Amendments passed in 1988:
Monitor patient identifiers on labels
Developed technical standards and laboratory practice guidelines
Restrict laboratory testing practices
Regulate laboratory sites that test only non-human specimens
Which study, performed earlier this century, established that the fourteenth-century Black Plague was spread from rats to humans via fleas?
Descriptive
Epidemiological
Experimental
Observational
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