General Pharmacology Quiz Part 1

By:Mohamed Mamdouh 

It is a chemical substance that alters body functions and can be used for diagnosis, prevention or treatment of disease.

The drug replaces an existing physiological process

The drug interferes with a physiological process.

The drug stimulates a physiological process

What kind of drugs we get from Animals

What kind of drugs we get from Microorganism

What kind of drugs we get from Plants

Thiazides from Sulfonamides represents what kind of drug discovery ?

Streptomycin from microorganisms represents what kind of drug discovery ?

Accidental discovery of penicillin represents what kind of drug discovery ?

They are the studies of the biological and therapeutic effects of drugs and their mechanism of action, I.e. What drugs do to the organism.

They are the studies of the Absorption, Distribution, Metabolism and Excretion of drugs

An inert substance given just to please the patient

Used in clinical trials to distinguish between the actual physiological or psychological effects of a treatment

Additional pharmacologically inactive chemicals added to oral dosage forms

The time for the minimum concentration of drug to cause the initial pharmacological response.

When the drug reaches its highest blood or plasma concentration.

Is the length of time that the drug maintains the pharmaceutical response

Identifies the margin of safety of the drug and gives idea about the safety of the drug

Which of the following drugs is the safest according to the Therapeutic index

Patients do not accurately follow physician's instructions in taking medication resulting in under- or over-utilization of the prescribed drug

Specific cellular macromolecule that interact with a ligand to produce a response

Type of receptor when open resulting in the flow of sodium and calcium ions into and out of the cell.

Type of receptor bind with guanosine triphosphate (GTP).

Type of receptor causing an enzyme inside the cell to initiate a physiological response

Type of receptor binds to DNA within the nucleus of the cell and alters gene expression to initiate a physiological response

What is the primary characteristic of an agonist in pharmacology?

What is the role of an antagonist in pharmacology?

In pharmacology, what term is used to describe a drug that has both agonistic and antagonistic properties?

In pharmacology, what term is used to describe the maximum therapeutic effect that a drug can achieve?

Which term describes a drug that binds to a receptor but produces a smaller response than the endogenous ligand?

What is the term for a substance that binds to a receptor without activating it, preventing the binding of other molecules?

In pharmacology, what is the opposite of an antagonist?

Which type of antagonist competes with the agonist for binding to the same receptor site?

Which type of antagonist prevent activation of the receptor by the agonist from another receptor

In absence of the agonist, it activates the empty receptor, but with lower efficacy than that of a full agonist.

What is the term for a drug interaction in which the combined effect of two drugs is greater than the sum of their individual effects?

What is the term for a drug interaction when two drugs are taken together and one of them intensifies the action of the other.

Which term describes a situation where one drug decreases the effect of another drug when taken together?

Which type of drug interaction occurs when two drugs with similar therapeutic effects are combined, leading to an effect equal to the sum of their individual effects?

What term is used to describe an unexpected and harmful reaction to a drug at normal doses?

Which of the following is an example of a type A adverse drug reaction?

What is the term for an exaggerated response to a drug due to repeated administration, requiring an increased dose to maintain the same effect?

Which of the following is a characteristic of Type A adverse drug reactions?

Which of the following is an example of a Type B adverse drug reaction?

Adverse effect may occur even after stopping drug by Carcinogenicity and Teratogenesis:

Adverse effects following withdrawal of some drugs represent which type

Drug allergy is .....................and occur in............... Of patients