Patho Midterm
Pathophysiology Midterm Quiz
Test your knowledge on the pathophysiological aspects of respiratory diseases with our comprehensive quiz. Designed for students, healthcare professionals, and anyone interested in enhancing their understanding of pulmonary conditions, this quiz covers a wide range of topics to challenge your expertise.
- 93 in-depth questions
- Multiple-choice format
- Covers common respiratory diseases
Reversible bronchial airway smooth muscle constriction, airway inflammation caused by eosinophils and other inflammatory cells, and increased airway responsiveness to an assortment of stimuli are anatomic alterations associations with:
Asthma
Chronic Bronchitis
Cystic Fibrosis
Emphysema
All of the following diseases are associated with mucus production EXCEPT:
Cystic Fibrosis
Chronic Bronchitis
Emphysema
Bronchiectasis
What is the cause of barrel chest in obstruction diseases?
Hyperoxia
Polycythemia
Air Trapping
Chronic hypoxemia
A “Pink Puffer” refers to a patient with:
Emphysema
Bronchiectasis
Asthma
Chronic Bronchitis
A “Blue Bloater” refers to a patient with:
Asthma
Chronic Bronchitis
Emphysema
Bronchiectasis
Which of the following would confirm the presence of an obstructive disease?
Increased FEV1 and Decreased FEV1%
Decreased FEV1 and Increased FEV1%
Increased FEV1 and Increased FEV1%
Decreased FEV1 and Decreased FEV1%
Which of the following is consistent with obstructive diseases and air trapping?
Increased RV and Decreased TLC
Decreased RV and Increased TLC
Increased RV and Increased TLC
Decreased RV and Decreased TLC
What ABG value would NOT be consistent with chronic ventilatory failure in COPD?
PaCO2 < 35mmHg
PaCO2 > 45mmHg
HCO3 > 26 mEq/L
PH 7.38
Your patient has status asthmaticus. They have shallow, labored breathing, wheezing, accessory muscle use, HR 120 bpm, and RR 8bpm. Which of the following ABG’s would you expect?
Acute ventilatory failure with hypoxemia
Chronic ventilatory failure with hypoxemia
Acute metabolic acidosis with hypoxemia
Acute alveolar hyperventilation on chronic ventilatory failure
The patient has the follow findings: Inspections: thin, barrel chested, using accessory muscles, pursed lip breathingPalpation: Decreased tactile fremitus, and decreased chest expansionPercussion: HyperresonanceAuscultation: Diminished breath sounds with prolonged expirationsABG: Chronic ventilatory failure with hypoxemiaDLCO: decreasedThese findings are consistent with:
Chronic Bronchitis
Emphysema
Bronchiectasis
Cystic Fibrosis
Your patient has the following findings:Inspection: Stocky, Overweight, peripheral edema, distended neck veins, productive cough with purulent sputum, digital clubbing, and cyanotic nail bedsPalpation: normalPercussion: normalAuscultation: crackles and wheezesABG: chronic ventilatory failure with hypoxemiaDLCO: normal Theses findings are consistent with:
Chronic Bronchitis
Cystic Fibrosis
Bronchiectasis
Emphysema
Your 12-year-old female patient has the following findings:Inspection: HR 130, RR 28, accessory muscle use, pulsus paradoxus, cough with excessive thick, white sputumPalpation: decreased tactile fremitusPercussion: hyperresonanceAuscultation: expiratory wheezesABG: Acute alveolar hyperventilation with mild hypoxemiaPEFR: DecreasedThese findings are consistent with:
Chronic Bronchitis
Bronchiectasis
Cystic fibrosis
Asthma
Your 75-year-old male patient has the following findings:Inspection: Increased HR, RR, and SpO2 88%, pursed lip breathing, barrel chested, cyanotic, coughing up large amounts of foul sputum that settles into 3 layers of a 24- hr periodPalpation: decreased tactile and vocal fremitusPercussion: HyperresonanceAuscultation: crackles and wheezingThese findings are consistent with:
Chronic Bronchitis
Asthma
Cystic Fibrosis
Bronchiectasis
Which of the following physiologic features contribute to Cor Pulmonale? 1. Polycythemia 2. Pulmonary vasoconstriction 3. Increased right heart work 4. Moderate to severe hypoxemia
2, 3, and 4 only
1, 2, 3, and 4
1 and 3
1, 2, and 3 only
Which of the following may be noticed about the breathing pattern of a patient with an emphysema episode?1. Prolonged expiratory phase2. May brace himself on table (tripod)3. Purse lip breathing4. May be unable to say more than a few words at once time/breath
1, 3, and 4 only
2, 3, and 4 only
1, 2, and 4 only
1, 2, 3, and 4
Which of the following causes abnormal volumes and capacities in obstructive diseases?
Air Trapping
Translucencies on CXR
Decreased Airway resistance
Increased HCO3
If a beta2- agonist agent and an anticholinergic agent were administered concurrently to a patient during an acute asthma episode, what results would be expected?
Airway edema will increase
Bronchial smooth muscle relaxation will occur
The medications oppose each other, resulting in no airway changes
Bronchial smooth muscle contraction will occur
Severe bronchiectasis is associated with all of the following EXCEPT:
Cor Pulmonale
Polycythemia
Vesicular breath sounds
Distended neck veins
All of the following can be used in the diagnosis of cystic fibrosis EXCEPT:
Chronic lung infections from an early age
An elevated potassium level in the sweat
An elevated chloride level in the sweat
Genetic testing of the patient and/or parents
Which of the following are anatomic alterations of the lungs found with emphysema?1. Air trapping and hyperinflation2. Mucus plugging3. Decreased surface area for gas exchange4. Weakened respiratory bronchioles
1 and 2 only
2 and 4 only
1, 3, and 4 only
1, 2, 3, and 4
Which of the following are anatomic alterations to the lungs are found with chronic bronchitis?1. Increased size of submucosal bronchial glands2. Destruction of pulmonary capillaries3. Chronic bronchial wall inflammation and thickening4. Bronchospasm
2 and 3 only
2 and 4 only
1, 2, and 3 only
1, 3, and 4 only
What finding on a chest radiograph would be expected during a prolonged asthma episode?1. Depressed diaphragms2. Increased AP diameter3. Asymmetrical lung fields4. Translucent lung fields
3 and 4 only
1, 2, 3, and 4
1, 2, and 4 only
1 and 2 only
A patient comes into the ER with shortness of breath and wheezing. Which of the following medications would be most appropriate at this time?
Albuterol
Salmeterol
Dornase Alfa
Budesonide
A 7-year-old female presents to the ER with SOB, dyspnea, and accessory muscle use. Your immediate evaluation revels tachycardia, tachypnea, crackles, and strong cough with small amounts of green sputum. SpO2 of 85% on room air. Patient history includes an elevated sweat chloride test and chromosome 7 genetic mutation. The patient’s disease process is:
Bronchiectasis
Cystic fibrosis
COPD
Asthma
Which of the following are commonly cultured from the mucus in the tracheobronchial tree of a patient with cystic fibrosis?1. Klebsiella Pneumoniae2. Pseudomonas Aeruginosa3. Haemophilus Influenzae4. Staphylococcus Aureus
1 and 2 only
2 and 4 only
1, 2, and 3 only
2, 3, and 4 only
Which of the following conditions is common in Cystic Fibrosis?
Spontaneous Pneumothorax
Cardiogenic Pulmonary Edema
Pleural Effusion
Congestive Heart Failure
Which of the following are associated with Status Asthmaticus?1. Increased airway resistance2. Responds well to bronchodilator therapy3. Acute ventilatory failure4. Rapid deterioration
2 and 3 only
1, 3, and 4 only
1 and 4 only
1, 2, 3, and 4
Cystic Fibrosis patients can have all of the following EXCEPT:
Tendency for status asthmaticus
Excessive, viscous pulmonary secretions
Malnutrition
Meconium ileus (bowel obstruction)
After the inhalation of a bronchodilator, what percentage change in peak expiratory flow (PEFR) would be required to demonstrate reversible airflow limitation consistent with asthma?
>20%
20%
+10%
10%
Which of the following are used to confirm a diagnosis of COPD?1. Presence of a chronic cough2. Chronic exposure to environmental smoke3. Sweat chloride test4. Decreased FEV1 and FEV1%
1 and 2 only
3 and 4 only
1, 2, and 4 only
1, 3, and 4 only
A patient has a lung infection with Pseudomonas Aeruginosa. What antibiotics should be used against it?
Dornase Alfa (Pulmozyme)
Levalbuterol (Xopenex)
Pentamidine (NebuPent)
Tobramycin (TOBI)
Your patient has rhinosinusitis, dextrocardia, and bronchiectasis. He is likely to have which of the following diseases?
Cystic Fibrosis
Kartegener’s Syndrome
Pierre Robin Syndrome
COPD
A patient with long-standing bronchiectasis also has bacterial pneumonia. Which of the following blood test results would be expected?1. Decreased WBC2. Increased hemoglobin and hematocrit3. Decreased RBC4. Elevated WBC
1 and 2 only
2 and 4 only
2, 3, and 4 only
3 and 4 only
What is the term for a fall in systolic blood pressure in excess of 10 mmHg on inspiration than on expiration?
Pulsus Paradoxus
Stage 1 hypotension
Hoover’s sign
Swanson’s phenomenon
In the United States, the primary factor leading to the development of COPD is:
Alpha 1 antitrypsin deficiency
Socioeconomic status
Recurrent respiratory infections
Tobacco smoking
A mother brought her 2-year-old son to the physician. He has been coughing up secretions and having wheezy breathing ever since choking on food 6 months ago. The physician diagnosed the boy with bronchiectasis. What could be the cause?
Cystic Fibrosis
Aspiration
Measles
Asthma
History: 17-year-old male student with 5th ED admission for acute SOB, cough with thick sputum. Physical: Patient agitated and in distress, severe wheezing and crackles on auscultationABG: pH 7.57, PaCO2 28 mmHg, PaO2 68 mmHg on 6LPM nasal cannulaLab: mucoid sputum contains plugs and spiralsWBC: high eosinophilsCXR: Mild hypertensionWhich of the following is the most likely diagnosis?
Emphysema
Cystic Fibrosis
Asthma
Chronic Bronchitis
The respiratory therapist is monitoring the blood pressure of a patient in the ER and notes that the blood pressure is 15 mmHg less on inspiration than on expiration. Which of the following would most likely result in this finding?
The patient is having an MI
The patient is hypovolemic
The patient is having a severe exacerbation of asthma
The patient has a pulmonary embolism
After collecting a 24-hour sputum sample, the RCP notices that there are 3 layers to the sample. Which disease typically presents this characteristic?
Asthma
Acute Bronchitis
Emphysema
Bronchiectasis
Which of the following statements accurately describes emphysema?
It is closely associated with cystic fibrosis
It characterized by alveolar wall destruction
It is reversible and preventable
It is characterized by thick secretions and mucus plugging
Which of the following are associated with extrinsic asthma?1. Animal dander2. Mold3. Emotional stress4. Male gender
1 and 2 only
1, 2, and 3 only
1, 3, and 4 only
2 and 3 only
What type of emphysema creates an abnormal enlargement of all structures distal to the terminal bronchioles?
Centrilobular emphysema
Alpha 1 protease inhibitor deficiency emphysema
ZZ phenotype emphysema
Panlobular emphysema
This disease process is known by the public as “Valley Fever”.
Candida Ablicans
Blastomycosis
Coccidioidomycosis
Histoplasmosis
Mycobacterium tuberculosis is most readily transmitted through:
Coughing
Accidental direct inoculation
Shaking hands and then rubbing your eye
Drinking milk from or the milking of infected cows
All of the following may be causes of cardiogenic pulmonary edema EXCEPT:
Dysrhythmias
Systemic hypertension
Excessive fluid administration
Lymphatic insufficiency
Congenital heart defects
A patient has a pleural effusion related to her pneumonia. Which of the following should the RT recommend to treat the pleural effusion?
Hyperinflation therapy
Thoracentesis
Percussion and postural drainage
Supplemental oxygen
Breath sounds that indicate sputum and air colliding in the smallest diameter of the tracheobronchial tree would be described as:
Stridor
Pleural Friction Rub
Crackles
Wheezing
A skin test is available to confirm which of the following fungal infections?
Coccidioidomycosis
Tuberculosis
Blastomycosis
Pseudomonal infection
Which of the following are predisposing factors to aspiration of oropharyngeal secretions and/or gastric contents into the lower respiratory tract?1. General anesthesia2. Head trauma3. Seizure disorder4. Alcohol abuse
1, 2, and 3 only
1 and 2 only
1, 3, and 4 only
1, 2, 3, and 4
Fungal lung infections are usually spread by:
Contact with infected sputum
Inhaling spores
Blood
Inhaling infected droplets
Management of cardiogenic pulmonary edema includes giving a patient which of the following types of medications? 1. Afterload reducer 2. Inotropic agents 3. Preload reducer 4. Chronotropic agents
2 and 3 only
3 and 4 only
1, 2, and 3 only
1 and 4 only
After cleaning out his chicken coop, a farmer has developed a fungal lung infection. What type of infections is it most likely to be?
Coccidioidomycosis
Blastomycosis
Histoplasmosis
Cryptococcal infections
A patient who has an uncontrolled tuberculosis infection will show all of the following signs EXCEPT:
Night sweats
Bloody sputum
Weight loss
High Fever
What part of the lungs are most commonly affected by a fungal infection?
Mainstem bronchi
Lower lobes
Upper Lobes
Lingula
A key feature of a productive cough with active TB as compared to active pneumonia is:
Smell of sputum
Hemoptysis
Viscosity
Color of sputum
Which of the following pathogens microbes are responsible for Hospital Acquired Pneumonia? 1. Streptococcus 2. Staphylococcus 3. Haemophilius Influenza 4. Legionella 5. Klebsiella 6. Pseudomonas
2, 4, and 5 only
2, 5, and 6 only
1, 5, and 6 only
1, 3, and 4 only
A patient with pulmonary edema is cyanotic and complaining of difficulty breathing. What should be recommended by the RT?
Have the patient use pursed lip breathing
Provide supplemental oxygen
Begin bronchopulmonary hygiene therapy
Begin mechanical ventilation
An antifungal medication used to treat candida albicans is:
Amphotericin B
Nystatin
Fluticasone
Thrush
During the early stages of lung abscess, the pathologic process is identical to that of:
Bronchopulmonary dysplasia
Pulmonary edema
Pulmonary fibrosis
Acute pneumonia
Bedside patient evaluation during active pneumonia would include which assessments? 1. Bradycardia 2. Hypoxemia 3. Dyspnea 4. Alveolar Hypoventilation
1 and 2 only
1 and 3 only
2 and 3 only
1, 2, 3, and 4
The drug of choice for the treatment of fungal lung disease:
Penicillin
Tertacycline
Ketoconazole
Amphotericin B
All of the following are causes of cardiogenic pulmonary edema EXCEPT:
Myocardial Infarction
Allergic reaction to drugs
Mitral valve disease
Congenital heart disease
The major pathologic or structural changes seen in the lungs with pulmonary edema include: 1. Atelectasis 2. Bronchospasm 3. High surface tension of alveolar fluids 4. Alveolar flooding
2 and 3 only
1 and 4 only
1, 3, and 4 only
1, 2, and 3 only
Physical assessment findings on a patient with pneumonia would include all of the following EXCEPT:
Bradycardia
Increased vocal fremitus
Dull percussion note
Whispered pectoriloquy
The 6 month drug treatment protocol for tuberculosis includes: 1. Amphotericin B 2. Isoniazid 3. Ethambutol 4. Rifampin 5. Penicillin 6. Pyrazinamide
2, 3, 4 and 5 only
1, 3, 4 and 5 only
1, 2, 5 and 6 only
1, 4, 5 and 6 only
2, 3, 4, and 5 only
2, 3, 4, and 6 only
In Which of the following ways is tuberculosis generally not spread?
Sharing utensils and glassware with an infected person
Laceration with contact of infected secretions during post mortem autopsy
Inhaling droplets of aerosol from an infected person
Drinking unpasteurized milk from cattle infected with the pathogen
Fungal diseases cause which type of pulmonary disorder?
A drug resistant bacterial infection
A chronic restrictive disorder
An acute obstructive disorder
A chronic obstructive disorder
Which of the following conditions can result in a lung abscess? 1. Penetrating chest wound 2. Septic embolism 3. Aspirated foreign body 4. Bronchogenic cyst
3 and 4 only
1 and 2 only
1, 2, and 4 only
1, 2, 3 and 4
Risk factor predisposing a person to TB including all of the following EXCEPT:
African American or Hispanic heritage
Being immunosuppressed
Having HIV/AIDS
Malnutrition
A patient with cardiogenic pulmonary edema would be expected to have all of the following chest radiograph findings EXCEPT:
Depressed diaphragms
Bilateral “butterfly” pattern fluffy inflitrates
Cardiomegaly
Pleural effusion
The preferred stain that is used to identify the TB organism is called:
Fluorescent acid-fast stain
Zeihl neelsen
Gentian violet
Gram stain
VAP is defined as pneumonia that develops:
More than 48 to 72 hours after mechanical ventilation is started
Between 24 to 48 hours after endotracheal intubation
Less than 24 hours after mechanical ventilation is started
More than 48 to 72 hours after endotracheal intubation
Which of the following can cause pneumonia? 1. Bacteria 2. Viruses 3. Prions 4. Fungi
1 and 2 only
1, 2, 3, and 4
2 and 3 only
1, 2, and 4 only
Major lung structural changes with pneumonia include: 1.Alveolar inflammation 2.Bronchoconstriction 3.Alveolar Consolidation 4.Emphysematic bulla
1 and 2 only
2 and 3 only
1 and 4 only
1 and 3 only
Which of the following can occur when tissue necrosis occurs in the lung abscess? 1.Fluid can rupture into a bronchus 2.Broncholithiasus can occur 3.Bronchospasm can close off the affected bronchi 4.Fluid can rupture into the intrapleural space
1 and 4 only
1, 2 and 3 only
1 and 2 only
3 and 4 only
A patient has noncardiogenic pulmonary edema. What chest radiograph findings would be expected? 1.“Bat’s wings” pattern fluffy infiltrates 2.Normal cardiac silhouette 3.Fluffy densities near the hilum 4.Pleural effusion
1 and 3 only
1 only
1, 2 and 3 only
3 and 4 only
A first line agent used to treat a TB infection is:
Gentamycin
Isoniazid
Streptomycin
Penicillin
What medication is used to treat a person who has converted to a positive TB skin test but does not have active disease?
Isoniazid
Dornase Alfa
Tetracycline
Virazole
A patient has bilateral pneumonia. What findings can be expected on the CT scan? 1.Depressed diaphragms 2.Elongated heart 3.Air bronchogram 4.Consolidation
1 and 2 only
2, 3, and 4 only
3 and 4 only
1, 2, 3, and 4
Overall, most cases of pneumonia are caused by:
Viruses
Gram negative bacteria
Fungi
Protozoa
The term for the types of ventilation reflective of a higher than normal CO2 in the arterial blood:
Hyperventilation
Hypoventilation
Hyphyventilation
SuperHyphyventilation
A patient with an advance pulmonary fungal infection has cor pulmonale. How will this manifest itself?
Asymmetrical chest movement when breathing
Wheezy breath sounds
Poor skin turgor
Distended neck veins
Your patient with pneumonia is experiencing acute alveolar hyperventilation. Which of the following would you expect? 1.High minute ventilation 2.Low minute ventilation 3.High PaCO2 4.Low PaCO2
2 and 3 only
1 and 4 only
1 and 3 only
2 and 4 only
Fungal infections of the lungs is closest in similarity to:
ILD
Pleural disease
Tuberculosis
Bronchiectasis
If a patient has pneumonia, which of the following can increase the risk of life-threatening illness or death? 1.Weakened immune system 2.COPD 3.Marfan’s syndrome 4.Heart disease
1 and 3 only
1, 2, and 4 only
2 and 4 only
1, 2, and 3 only
What is the normal hydrostatic pressure in the pulmonary capillaries?
0 to 5 mmHg
5 to 10 mmHg
10 to 15 mmHg
15 to 20 mmHg
Your patient has been found to have TB in several organs of the body. What term is used to describe this situation?
Primary TB
Postprimary TB
Disseminated TB
Multiorgan TB
Patients with pulmonary edema often awaken with severe dyspnea after several hours of sleep. What is this called?
Paroxysmal nocturnal dyspnea
Paroxysmal nocturnal apnea
Sleep dyspnea
Sleep apnea
What is the name of the protective wall that surrounds and encases lung tissue infected with tuberculosis?
Tubercle
Cavity
Abscess
Bleb
Which of the following is/are associated with pneumonia? 1.Decreased tactile and vocal fremitus 2.Decreased PEFR 3.Increased VC 4.Dull percussion note
1 and 2 only
1 and 4 only
2 and 4 only
1, 2, and 4 only
What ABG results would be consistent with extensive tuberculosis?
Acute alveolar hyperventilation with hypoxemia
Chronic ventilatory failure with hypoxemia
Acute ventilatory failure with hypoxemia
Metabolic alkalosis
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