Im2
Immune System Mastery Quiz
Test your knowledge of the immune system with our comprehensive quiz! This quiz encompasses a variety of topics related to immunology, including the fun
Whether you're a student looking to reinforce your studies, a teacher wanting to challenge your students, or just a curious learner, you'll find this quiz engaging and informative. Key features include:
- 73 carefully curated questions
- Diverse question types
- Instant feedback on answers
39. The function of immune system is to response
σ� Can be facilitated by antibodies
σ� Mediated the humoral and cellular immune system
σ� Facilitated by T-cells
σ� All answers
8. All of the following are true with respect to IgE molecules, EXCEPT :
They are the principal immunoglobulin class involved in allergic reactions.
σ� They are involved in mediating anti-parasitic immune responses.
σ� They will cross the placenta and fix complement)
σ� They can effect the release of histamine
91. Which of the following is antiviral:
σ� Lysozyme
σ� Interferon
σ� Protein
σ� Hormone
92. Identity the phagocytic cells from the following combinations
σ� Macrophage and neutrophil
σ� Lymphocyte and eosinophil
σ� Macrophage and eosinophil
σ� Eosinophil and neutrophil
93. Histamine is secreted by:
σ� Epithelial cell
σ� Mast cells
σ� Red blood cells
σ� White blood cells
94. Humoral immunity consists of:
σ� Normal cells
σ� Pathological cells
σ� Cytotoxic cells
σ� Immunoglobulins
95. Complement deficiencies of C3b can cause
σ� Overproduction of C2b
σ� Glucose oxidase deficiency
σ� Predisposition to SLE
σ� Bacterial infection
96. Which of the following causes AIDS ?:
σ� Bacteria
σ� Fungus
σ� Retrovirus
σ� TMV
97. Thymus growth occurs up to:
σ� 17 years
σ� 12 years
σ� 5 years
σ� 30 years
98. Complements are chemically
σ� Glycogens
σ� Glycoproteins
σ� Lipoproteins
σ� Proteins
99. Hyper variability regions are present in:
σ� Heavy chain only
σ� Light chain only
σ� Heavy and light
σ� Dark chain
100. Organ transplantation of human from one place to another is called:
σ� Autograft
σ� Allo-graft
σ� ISO-graft
σ� Xeno-graft
101. Graft between identical twins is called
σ� Xeno-graft
σ� Allograft
σ� Auto graft
σ� Iso graft
102. What is the term used to describe white blood cells migrating toward bacteria? :
σ� Zeiosis
σ� Phagocytosis
σ� Chemotaxis
σ� Phototaxis
103. Name the process a cell such as a neutrophil or a macrophage uses to ingest (eat) its prey.:
σ� Halitosis
σ� Chemotaxis
σ� Botulism
σ� Phagocytosis
104. What's a specific term for a bacterial or other foreign protein that initiates antibody production by the body?:
σ� Peptide
σ� MHC II molecule
σ� Complement
σ� Antigen
105. Which of the following bacteriocidal mechanisms is oxygen dependant?:
σ� NADPH oxidation
σ� Defensins
σ� Hydrolytic enzymes
σ� Lactoferrin
106. Pepsin cleaves what region of immunoglobulin?:
σ� Heavy chain
σ� Light chain
σ� Hinge region
σ� Heavy chain and Light chain
107. Papain cleaves what region of immunoglobulin?
σ� Heavy chain
σ� Light chain
σ� Hinge region
σ� Heavy chain and Light chain
108. Biological properties of C5a are
σ� Chimotactic activity
σ� Anaphylactic much potent
σ� Attract and activate PMN
σ� All answers
109. Which of the following binds to an Fc receptor on mast cells and basophils?:
σ� IgA
σ� IgM
σ� IgE:
σ� IgG
110. Which of the following is a β structural chain in class I MHC?:
σ� β1
σ� α1
σ� α2
σ� β2 –microglobin
111. Which of the following is NOT a structural chain in class II MHC
σ� α1
σ� α2
σ� α3
σ� β 1
112. The initial complement component that is bound by complement-fixing antibodies is:
σ� C1q
σ� C1s
σ� C3b
σ� C5a
113. Molecule binding to their receptors at high affinity
σ� Cytokines
σ� Antibody
σ� Antigen
σ� All answer
114. Which of the following components of the innate immune system involves the release of histamine
σ� Neutrophil
σ� Eosinophil
σ� Macrophage
σ� Tissue mast cell
115. Which of the following components of the adaptive immune system secretes immunoglobulin (Ig)?:
σ� Activated B cell (plasma cell)
σ� CD4+ activated T cell
σ� CD8+ cytotoxic T cell (CTL)
σ� Resting lymphocytes (B cell, T cell)
116. The region of immunoglobulin term: Binds to various cellular receptors and to complement:
σ� Fab region
σ� Fc region
σ� Light chain
σ� Heavy chain
117. The C5 convertase of Classic and Lectin pathway is:
σ� C4b2a4b
σ� C4b2b3a
σ� C4b2a3b
σ� C3bBb3b
118. The C5 convertase of Alternative pathway is:
σ� C4b2a4b
σ� C4b2b3a
σ� C4b2a3b
σ� C3bBb3b
119. The Complement that gives Anaphylotoxin much potent is:
σ� C4a
σ� C5a
σ� C2b
σ� C3a
120. Which of the following immunoglobulin is first synthesized in an immune system to response an pathogen?:
IgM
σ� IgA
σ� IgG
σ� IgE
121. Which of the following statement is related to IgG physiology in humans?:
It is confined to the bloodstream, giving the host protection against blood-borne pathogens.
σ� It can be arranged to resemble a pentamer of five distinct immunoglobulin molecules.
σ� Opsonisation through FcR on macrophages occurs with IgG2 and IgG4.
σ� IgG crosses the placental barrier, and thereby provides passive immunity to the fetus
122. Which of the following antibody fragments consists of a dimer of the heavy-chain constant region but lacks the CH1 domains
σ� F(ab)’
σ� F(ab)'
σ� Fab
σ� Fc
123. Which of the following statements about leukocyte function is false?
σ� Leukocytes are cells of the immune response.
σ� Neutrophils phagocytose pathogens .
σ� Eosinophils kill parasites.
σ� Eosinophils release histamine
124. Killed Whole-Organism is used to prepare vaccines below, EXCEPT
σ� Polio
σ� Pertussis
σ� Hepatitis B
σ� Rabies
125. Microbial Fragment Vaccines is used to prevent the diseases below, EXCEPT:
σ� Polio
σ� Haemophilus influenzae B
σ� Hepatitis B virus
σ� Neisseria meningitides
126. The family of Hepatitis B virus is named:
σ� Hepadnavirus
σ� Flavivirus
σ� Retrovirus
σ� CMV
127. Clinical abnormalities of the Immune system can result from the activities below:
σ� Neutrophils kill bacteria
σ� Abnormal lymphocyte proliferation
σ� Plasma cells secrete antibody
σ� T cell secrete cytokine
128. Which of the following is NOT a major feature (characteristic) of the adaptive immune system?:
σ� Specificity
σ� Diversity
σ� Memory
σ� Improvement
129. The following statement are function of immune system, EXCEPT
σ� Can be facilitated by antibodies
σ� Mediated the humoral and cellular response
σ� Facilitated by T-cells
σ� Allow pathogen to infect the bod
130. Which of the followings are TRUE regarding an Immune response
σ� The T3 complex is signal to the cell's interior to recognize antigen
σ� The T8 support MHC II in cytotoxic reactions
σ� The T4 support MHC class I in helper reactions
σ� The T4 secrete antibody
131. The component of immune system that can cause fever is :
σ� Complement
σ� Immunoglobulin
σ� T lymphocytes
σ� Macrophage
132. In a chronic infection of Hepatitis B, the typical serologic course are
σ� HBsAg
σ� HBcAb
σ� HBsAb
σ� HBsAg and HBcAb
133. Identity the phagocytic cells that have Toll like Receptor on their membrane:
σ� Macrophage
σ� Eosinophil
σ� Basophil
σ� Neutrophil
134. In acute infection of Hepatitis B, the typical serologic course are
σ� HBsAg
σ� HBcAb
σ� HBcAg
σ� HBsAb
135. The disease below can cause by autoimmune:
σ� Hepatitis
σ� Thalassemia
σ� Cancer
σ� SLE
136. The following cells are proliferated from myloid progenitor :
σ� B cells
σ� TH1
σ� Lymphocytes
σ� Dendritic cells
137. Intracellular pathogen is presented to the Tc by:
σ� MHC I
σ� MHC II
σ� Lymphocytes
σ� TH
138. Tumor Necrose Factor (TNF) produce by:
σ� Neutrophil
σ� Macrophage
σ� Tc
σ� Macrophage and Tc
139. Platelets can produce by those organs:
σ� Liver
σ� Spleen
σ� Bone marrow
σ� Thymus
140. Myeloid cells below lived in tissue:
σ� Macrophage
σ� Neutrophil
σ� Lymphocyte
σ� Basophil
141. Biological effect of Complement C5a is
σ� Neutrophil activation
σ� Opsonisation
σ� Inflammation
σ� Phagocytosis
142. Biological effect of Complement C2b is:
σ� Anaphylaxis
σ� Opsonisation
σ� Edema
σ� Phagocytosis
143. Biological effect of Complement C3a is
σ� Anaphylaxis
σ� Opsonisation
σ� Edema
σ� Phagocytosis
144. Biological effect of Complement C4a is regulated by:
σ� Factors H & I
σ� C3-INA
σ� C4-BP
σ� Factor I
145. The Complement that produce anaphylactic much more potent is:
σ� C2b
σ� C5a
σ� C4a
σ� C3a
146. Which immunoglobulin is used to test for blood group:
σ� IgG
σ� IgE
σ� IgA
σ� IgM
147. Which immunoglobulin is used to produce vaccine
σ� IgG
σ� IgE
σ� IgA
σ� IgM
148. The fragment of Antigen is called:
σ� Immunogen
σ� Hapten
σ� Antigenic determinant
σ� Immunoglbulin
149. How many receptors for antigen on the surface of T lymphocyte:
σ� 1
σ� 2
σ� 4
σ� 10
150. How many receptors for antigen on the surface of B lymphocyte
σ� 1
σ� 2
σ� 4
σ� 10
151. Where is the variable region of Immunoglobulin
σ� VL
σ� CL
σ� CH2
σ� CH3
152. The function of MHC class II is
σ� Recognized by CD4
σ� Recognized by the CD8
σ� Presentation Ag to Th cell
σ� Unable to carry antigen fragment
153. The function of LGL cell is:
σ� Response to bacteria infection
σ� Respose to tumor cells
σ� Response to antibody
σ� Kill pathogen
154. Which cells secreted most cytokine in innate immune
σ� T lymphocyte
σ� B lymphocyte
σ� Macrophage
σ� Plasma cell
155. The answers below are characteristic of antigen, EXCEPT
σ� Contain paratopes
σ� Contain epitopes
σ� Are toxin
σ� React with antibody
156. The following answers are true for IgM antibodies, EXCEPT
σ� Fix complement
σ� Anti infectious
σ� Cause of allergy
σ� Pentametric form
157. The following answers are true for phagocytosis, EXCEPT
σ� Supported by complement
σ� Opsonisation
σ� Ingest pathogen
σ� NK cell
158. The following activity is indicated T cell cytotoxic:
σ� MHC-II restricted
σ� MHC-I restricted
σ� B cell activation
σ� Epitope presented to CD4
159. Which cell is T helper:
σ� CD8
σ� CD14
σ� CD4
σ� CD15
160. Which cell is Monocyte:
σ� CD8
σ� CD14
σ� CD4
σ� CD15
161. Which cell is Granulocyte
σ� Basophil
σ� Monocyte
σ� Lymphocyte
σ� Macrophage
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