Part 3 Immunology(100-149) prof. keit vanseth
100. What's a specific term for a bacterial or other foreign protein that initiates antibody production by the body?:
Peptide
MHC II molecule
Complement
Antigen
101. Which of the following bacteriocidal mechanisms is oxygen dependant?:
NADPH oxidation
Defensins
Hydrolytic enzymes
Lactoferrin
102. Pepsin cleaves what region of immunoglobulin?:
Heavy chain
Light chain
Hinge region
Heavy chain and Light chain
103. Papain cleaves what region of immunoglobulin?:
Heavy chain
Light chain
Hinge region
Heavy chain and Light chain
104. Biological properties of C5a are:
Chimotactic activity
Anaphylactic much potent
Attract and activate PMN
All answers
105. Which of the following binds to an Fc receptor on mast cells and basophils?:
IgA
IgM
IgE:
IgG
106. Which of the following is a β structural chain in class I MHC?:
β1
α1
α2
β2 –microglobin
107. Which of the following is NOT a structural chain in class II MHC?:
α1
α2
α3
β 1
108. The initial complement component that is bound by complement-fixing antibodies is:
C1q
C1s
C3b
C5a
109. Molecule binding to their receptors at high affinity :
Cytokines
Antibody
Antigen
All answer
110. Which of the following components of the innate immune system involves the release of histamine?:
Neutrophil
Eosinophil
Macrophage
Tissue mast cell
111. Which of the following components of the adaptive immune system secretes immunoglobulin (Ig)?:
Activated B cell (plasma cell)
CD4+ activated T cell
CD8+ cytotoxic T cell (CTL)
Resting lymphocytes (B cell, T cell)
112. The region of immunoglobulin term: Binds to various cellular receptors and to complement:
Fab region
Fc region
Light chain
Heavy chain
113. The C5 convertase of Classic and Lectin pathway is:
C4b2a4b
C4b2b3a
C4b2a3b
C3bBb3b
114. The C5 convertase of Alternative pathway is:
C4b2a4b
C4b2b3a
C4b2a3b
C3bBb3b
115. The Complement that gives Anaphylotoxin much potent is:
C4a
C5a
C2b
C3a
116. Which of the following immunoglobulin is first synthesized in an immune system to response an pathogen?:
IgM
IgA
IgG
IgE
117. Which of the following statement is related to IgG physiology in humans?:
It is confined to the bloodstream, giving the host protection against blood-borne pathogens.
It can be arranged to resemble a pentamer of five distinct immunoglobulin molecules.
Opsonisation through FcR on macrophages occurs with IgG2 and IgG4.
IgG crosses the placental barrier, and thereby provides passive immunity to the fetus.
118. Which of the following statements about leukocyte function is false?:
Leukocytes are cells of the immune response.
Neutrophils phagocytose pathogens .
Eosinophils kill parasites.
Eosinophils release histamine .
119. Microbial Fragment Vaccines is used to prevent the diseases below, EXCEPT:
Polio
Haemophilus influenzae B
Hepatitis B virus
Neisseria meningitides
120. The family of Hepatitis B virus is named:
Hepadnavirus
Flavivirus
Retrovirus
CMV
121. Clinical abnormalities of the Immune system can result from the activities below:
Neutrophils kill bacteria
Abnormal lymphocyte proliferation
Plasma cells secrete antibody
T cell secrete cytokine
122. Which of the following is NOT a major feature (characteristic) of the adaptive immune system?:
Specificity
Diversity
Memory
Improvement
123. The following statement are function of immune system, EXCEPT:
Can be facilitated by antibodies
Mediated the humoral and cellular response
Facilitated by T-cells
Allow pathogen to infect the bod
124. Which of the followings are TRUE regarding an Immune response:
The T3 complex is signal to the cell's interior to recognize antigen
The T8 support MHC II in cytotoxic reactions
The T4 support MHC class I in helper reactions
T4 The secrete antibody
125. The component of immune system that can cause fever is :
Complement
Immunoglobulin
T lymphocytes
Macrophage
126. In a chronic infection of Hepatitis B, the typical serologic course are :
HBsAg
HBcAb
HBsAb
HBsAg and HBcAb
127. Identity the phagocytic cells that have Toll like Receptor on their membrane:
Macrophage
Eosinophil
Basophil
Neutrophil
128. The disease below can cause by autoimmune:
Hepatitis
Thalassemia
Cancer
SLE
129. The following cells are proliferated from myloid progenitor :
B cells
TH1
Lymphocytes
Dendritic cells
130. Intracellular pathogen is presented to the Tc by:
MHC I
MHC II
Lymphocytes
TH
131. Tumor Necrose Factor (TNF) produce by:
Neutrophil
Macrophage
Tc
Macrophage and Tc
132. Platelets can produce by those organs:
Liver
Spleen
Bone marrow
Thymus
133. Myeloid cells below lived in tissue:
Macrophage
Neutrophil
Lymphocyte
Basophil
134. Biological effect of Complement C5a is:
Neutrophil activation
Opsonisation
Inflammation
Phagocytosis
135. Biological effect of Complement C2b is:
Anaphylaxis
Opsonisation
Edema
Phagocytosis
136. Biological effect of Complement C3a is:
Anaphylaxis
Opsonisation
Edema
Phagocytosis
137. Biological effect of Complement C4a is regulated by:
Factors H & I
C3-INA
C4-BP
Factor I
138. The Complement that produce anaphylactic much more potent is:
C2b
C5a
C4a
C3a
139. Which immunoglobulin is used to test for blood group:
IgG
IgE
IgA
IgM
140. Which immunoglobulin is used to produce vaccine:
IgG
IgE
IgA
IgM
141. The fragment of Antigen is called:
Immunogen
Hapten
Antigenic determinant
Immunoglbulin
142. How many receptors for antigen on the surface of T lymphocyte:
1
2
4
10
143. How many receptors for antigen on the surface of B lymphocyte:
1
2
4
10
144. Where is the variable region of Immunoglobulin?:
VL
CL
CH2
CH3
145. The function of MHC class II is:
Recognized by CD4
Recognized by the CD8
Presentation Ag to Th cell
Unable to carry antigen fragment
146. The function of LGL cell is:
Response to bacteria infection
Respose to tumor cells
Response to antibody
Kill pathogen
147. Which cells secreted most cytokine in innate immune:
T lymphocyte
B lymphocyte
Macrophage
Plasma cell
148. The answers below are characteristic of antigen, EXCEPT:
Contain paratopes
Contain epitopes
Are toxin
React with antibody
149. The following answers are true for IgM antibodies, EXCEPT:
Fix complement
Anti infectious
Cause of allergy
Pentametric form
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