Part 3 Immunology(100-149) prof. Keit vanseth
Immunology Mastery Quiz
Test your knowledge of immunology with our comprehensive quiz! With 50 carefully crafted questions, you'll explore key concepts, mechanisms, and terminology related to the immune system.
This quiz is perfect for students, educators, and professionals looking to refresh their understanding of immunology. Topics include:
- Innate and adaptive immune responses
- Immunoglobulin structure and fun
ctions - Complement pathways
- Autoimmune diseases
100. What's a specific term for a bacterial or other foreign protein that initiates antibody production by the body?:
σ½ Peptide
σ½ MHC II molecule
σ½ Complement
σ¾ Antigen
101. Which of the following bacteriocidal mechanisms is oxygen dependant?:
σ¾ NADPH oxidation
σ½ Defensins
σ½ Hydrolytic enzymes
σ½ Lactoferrin
102. Pepsin cleaves what region of immunoglobulin?:
σ½ Heavy chain
σ½ Light chain
σ¾ Hinge region
σ½ Heavy chain and Light chain
103. Papain cleaves what region of immunoglobulin?:
σ¾ Heavy chain
σ½ Light chain
σ½ Hinge region
σ½ Heavy chain and Light chain
104. Biological properties of C5a are:
σ½ Chimotactic activity
σ½ Anaphylactic much potent
σ½ Attract and activate PMN
σ¾ All answers
105. Which of the following binds to an Fc receptor on mast cells and basophils?:
σ½ IgA
σ½ IgM
σ¾ IgE:
σ½ IgG
106. Which of the following is a β structural chain in class I MHC?:
σ½ β1
σ½ α1
σ½ α2
σ¾ β2 –microglobin
107. Which of the following is NOT a structural chain in class II MHC?:
σ½ α1
σ½ α2
σ¾ α3
σ½ β 1
108. The initial complement component that is bound by complement-fixing antibodies is:
σ¾ C1q
σ½ C1s
σ½ C3b
σ½ C5a
109. Molecule binding to their receptors at high affinity :
σ½ Cytokines
σ½ Antibody
σ¾ Antigen
σ½ All answer
110. Which of the following components of the innate immune system involves the release of histamine?:
σ½ Neutrophil
σ½ Eosinophil
σ½ Macrophage
σ¾ Tissue mast cell
111. Which of the following components of the adaptive immune system secretes immunoglobulin (Ig)?:
σ¾ Activated B cell (plasma cell)
σ½ CD4+ activated T cell
σ½ CD8+ cytotoxic T cell (CTL)
σ½ Resting lymphocytes (B cell, T cell)
112. The region of immunoglobulin term: Binds to various cellular receptors and to complement:
σ½ Fab region
σ¾ Fc region
σ½ Light chain
σ½ Heavy chain
113. The C5 convertase of Classic and Lectin pathway is:
σ½ C4b2a4b
σ½ C4b2b3a
σ¾ C4b2a3b
σ½ C3bBb3b
114. The C5 convertase of Alternative pathway is:
σ½ C4b2a4b
σ½ C4b2b3a
σ½ C4b2a3b
σ¾ C3bBb3b
115. The Complement that gives Anaphylotoxin much potent is:
σ½ C4a
σ¾ C5a
σ½ C2b
σ½ C3a
116. Which of the following immunoglobulin is first synthesized in an immune system to response an pathogen?:
σ¾ IgM
σ½ IgA
σ½ IgG
σ½ IgE
117. Which of the following statement is related to IgG physiology in humans?:
It is confined to the bloodstream, giving the host protection against blood-borne pathogens.
It can be arranged to resemble a pentamer of five distinct immunoglobulin molecules.
σ½ Opsonisation through FcR on macrophages occurs with IgG2 and IgG4.
σ¾ IgG crosses the placental barrier, and thereby provides passive immunity to the fetus.
118. Which of the following statements about leukocyte function is false?:
σ½ Leukocytes are cells of the immune response.
σ½ Neutrophils phagocytose pathogens .
σ½ Eosinophils kill parasites.
σ¾ Eosinophils release histamine .
119. Microbial Fragment Vaccines is used to prevent the diseases below, EXCEPT:
σ¾ Polio
σ½ Haemophilus influenzae B
σ½ Hepatitis B virus
σ½ Neisseria meningitides
120. The family of Hepatitis B virus is named:
σ¾ Hepadnavirus
σ½ Flavivirus
σ½ Retrovirus
σ½ CMV
121. Clinical abnormalities of the Immune system can result from the activities below:
σ½ Neutrophils kill bacteria
σ¾ Abnormal lymphocyte proliferation
σ½ Plasma cells secrete antibody
σ½ T cell secrete cytokine
122. Which of the following is NOT a major feature (characteristic) of the adaptive immune system?:
σ½ Specificity
σ½ Diversity
σ½ Memory
σ¾ Improvement
123. The following statement are function of immune system, EXCEPT:
σ½ Can be facilitated by antibodies
σ½ Mediated the humoral and cellular response
σ½ Facilitated by T-cells
σ¾ Allow pathogen to infect the bod
124. Which of the followings are TRUE regarding an Immune response:
σ¾ The T3 complex is signal to the cell's interior to recognize antigen
σ½ The T8 support MHC II in cytotoxic reactions
σ½ The T4 support MHC class I in helper reactions
σ½ T4 The secrete antibody
125. The component of immune system that can cause fever is :
σ¾ Complement
σ½ Immunoglobulin
σ½ T lymphocytes
σ½ Macrophage
126. In a chronic infection of Hepatitis B, the typical serologic course are :
σ½ HBsAg
σ½ HBcAb
σ½ HBsAb
σ¾ HBsAg and HBcAb
127. Identity the phagocytic cells that have Toll like Receptor on their membrane:
σ¾ Macrophage
σ½ Eosinophil
σ½ Basophil
σ½ Neutrophil
128. The disease below can cause by autoimmune:
σ½ Hepatitis
σ½ Thalassemia
σ½ Cancer
σ¾ SLE
129. The following cells are proliferated from myloid progenitor :
σ½ B cells
σ½ TH1
σ½ Lymphocytes
σ¾ Dendritic cells
130. Intracellular pathogen is presented to the Tc by:
σ¾ MHC I
σ½ MHC II
σ½ Lymphocytes
σ½ TH
131. Tumor Necrose Factor (TNF) produce by:
σ½ Neutrophil
σ½ Macrophage
σ½ Tc
σ¾ Macrophage and Tc
132. Platelets can produce by those organs:
σ½ Liver
σ½ Spleen
σ¾ Bone marrow
σ½ Thymus
133. Myeloid cells below lived in tissue:
σ¾ Macrophage
σ½ Neutrophil
σ½ Lymphocyte
σ½ Basophil
134. Biological effect of Complement C5a is:
σ¾ Neutrophil activation
σ½ Opsonisation
σ½ Inflammation
σ½ Phagocytosis
135. Biological effect of Complement C2b is:
σ½ Anaphylaxis
σ½ Opsonisation
σ¾ Edema
σ½ Phagocytosis
136. Biological effect of Complement C3a is:
σ¾ Anaphylaxis
σ½ Opsonisation
σ½ Edema
σ½ Phagocytosis
137. Biological effect of Complement C4a is regulated by:
σ½ Factors H & I
σ¾ C3-INA
σ½ C4-BP
σ½ Factor I
138. The Complement that produce anaphylactic much more potent is:
σ½ C2b
σ¾ C5a
σ½ C4a
σ½ C3a
139. Which immunoglobulin is used to test for blood group:
σ½ IgG
σ½ IgE
σ½ IgA
σ¾ IgM
140. Which immunoglobulin is used to produce vaccine:
σ¾ IgG
σ½ IgE
σ½ IgA
σ½ IgM
141. The fragment of Antigen is called:
σ½ Immunogen
σ½ Hapten
σ¾ Antigenic determinant
σ½ Immunoglbulin
142. How many receptors for antigen on the surface of T lymphocyte:
σ¾ 1
σ½ 2
σ½ 4
σ½ 10
143. How many receptors for antigen on the surface of B lymphocyte:
σ½ 1
σ¾ 2
σ½ 4
σ½ 10
144. Where is the variable region of Immunoglobulin?:
σ¾ VL
σ½ CL
σ½ CH2
σ½ CH3
145. The function of MHC class II is:
σ½ Recognized by CD4
σ½ Recognized by the CD8
σ¾ Presentation Ag to Th cell
σ½ Unable to carry antigen fragment
146. The function of LGL cell is:
σ½ Response to bacteria infection
σ¾ Respose to tumor cells
σ½ Response to antibody
σ½ Kill pathogen
147. Which cells secreted most cytokine in innate immune:
σ½ T lymphocyte
σ½ B lymphocyte
σ¾ Macrophage
σ½ Plasma cell
148. The answers below are characteristic of antigen, EXCEPT:
σ¾ Contain paratopes
σ½ Contain epitopes
σ½ Are toxin
σ½ React with antibody
149. The following answers are true for IgM antibodies, EXCEPT:
σ½ Fix complement
σ½ Anti infectious
σ¾ Cause of allergy
σ½ Pentametric form
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