The Nucleus

Which of these modifications does not occur to mRNA post-transcription
5' CAP added
3' polyadenation
Addition of a lipid
Splicing
The cytoskeleton within the nucleus is known as the
Nucleofilament
Nuclear lamina
Nucleoporin
Cytosolic fibrils
Which of these are components of a NPC
Scaffold nucleoporins
Cytosolic nucleoporins
Cytosolic fibrils
Nuclear basket
Channel nucleoporins
Nuclear helmet
Importins will bind to a cargo protein when what is present
NPC
NLS
NES
GEF
RanGTP is converted to RanGDP by what
RanGEF
RanGAP
RanGPA
NES
RanGDP is converted to RanGTP by what
RanGEF
RanGAP
RanGPA
NES
The exportin and cargo protein (which has an NES) bind to what to be exported from the nucleus
RanGEF
RanGAP
RanGTP
RanGDP
After releasing the cargo protein and its associated NLS, the importin and ____ are still bound and leave the nucleus by an NPC
RanGTP
RanGDP
NES
RanGEF
Importins and exportins travel through the NPC by sequential binding to what
Scaffold nucleoporins
FG repeats
Cytosolic fibrils
Nuclear basket
Importins and exportins are required for proteins over around what size
40KDa
50KDa
60KDa
70KDa
MRNA becomes mRNP by binding to adaptor proteins, these bind to
The spliced areas
The polyadenated areas
The 5' end (CAP complex)
The 3' end
Adaptor proteins allow export from the nucleus because
They reduce the size of the mRNP
Exportins need to bind to the adaptor proteins
They change the shape so it fits through the NPC
It allows for binding to RanGDP
Which rRNA is not synthesised by RNA polymerase I in the nucleolus
5S
5.8S
18S
28S
The nucleolus-synthesised ribosomal material combine to create
80s ribosomes
45s pre-rRNA
90s pre-ribosome
Tandem repeats
The addition of ribosomal proteins to 45S pre-rRNA generates
80S ribosomes
Tandem repeats
90S pre-ribosome
Non transcribed spacers
Ribosomes are made up of two subunits: the large and small. The small subunit contains
5S rRNA
5.5S rRNA
18S rRNA
28S rRNA
SnoRNPs are complimentary to areas of rRNA and modify it at the 90S pre-ribosome in what ways?
Polyadenation of 3'
Methylation of hydroxyl groups on ribose
Addition of a CAP to 5'
Conversion of uridine to pseudouridine
Cleavage of 45S pre-rRNA (splicing ETS and ITS)
Addition of helix
The cleavage of the ETS requires exoribonucleases, the ITS utilises
Intraribonucleases
Infraribonucleases
Endoribonucleases
Entraribonucleases
The 60S subunit (large) of the ribosome is transported to the cytoplasm to later bind to the 40S subunit (small) and is comprised of which rRNA
5S
5.8S
18S
28S
What organelle is the nuclear membrane often continuous with
Golgi apparatus
Mitochondria
Rough endoplasmic reticulum
Centrioles
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