Leprosy and skin bacterial infection

Leprosy and Skin Infections Quiz
Test your knowledge on leprosy and skin bacterial infections with this engaging quiz! Designed for healthcare professionals and students alike, this quiz covers crucial topics related to skin conditions, their diagnosis, and treatment options.
Key Features:
- Multiple choice questions
 - Focus on clinical presentations and management
 - Expand your understanding of complex dermatological issues
 
A padi farmer has an abscess with discharging sinus on the knee for 6 months and wound culture grew Burkholderia pseudomelia. The following statements are correct, EXCEPT •
He had  Melioidosis  which can be treated with antibiotics 
His brother  also has an ulcer and he is likely to have been infected by his brother  
The  doctor  treating him  used  Ashdown Transport media  when sending the  specimen to the laboratory 
He needs further test to look for infection of internal organs. 
Prolonged treatment form up to 6 months may be necessary.   
Pyogenic granuloma often occurs as a painless red nodule on the finger. Which one of the followings statements is TRUE? 
A number of species of organism  has been found on culture 
When it occurred during pregnancy (Granuloma partum), there is a risk of abortion. 
It is  treated with electrosurgery  
The  most appropriate antibiotic for its treatment is Gentamycin 
If untreated, it may spread to other part of body by contact. 
A young lady sees you for tender, erythematous, nodular lesion on both lower leg of 3 months duration. Her husband is treated for Pulmonary Tuberculosis. A skin biopsy was done, shows lobular panniculitis. Which one of the following statements is TRUE? •
She has Eryhthema induratum because Acid Fast Bacillus (AFB) is found on Zeihl-Nelson stain.
She has Eryhtema nodosum because her husband has Tuberculosis. 
She has  Erythema Induratum  because her  Montoux test is strongly reactive  
Her  chest X-ray will  show evidence of  Tuberculosis 
She has Erythema induratum because her  skin cleared with treatment with oral Prednisolone and Potassiun iodide 
A 40 year old man had a cut on his knee after a fall about 20 years ago and come to you with a complaint that the wound has never healed after consulting many doctors. A skin biopsy was done, shows it was Tuberculosis Verucossa cutis. Which one of the following statements is TRUE?
The histopathologist found Acid Fast Bacillus (AFB) in the tissue section. 
Mycobacteriun tuberculosis  grew on culture of the tissue 
The long history with fall, suggested that he can have a post-traumatic keloid. 
He needs treatment with Rifampicin, Pyrazamide and Isoniazid  
Chest X-ray usually shows evidence of active Tuberculosis
A healthy 20 year old man complains of hard painless growth on the dorsum of the right hand of 6 months duration. The following statements of his clinical problem are correct, EXCEPT:
He  works in a farm breeding Siamese Fighting Fish and the  one of the differential diagnosis is  Fish Tank  Granuloma 
Diagnosis of Fish Tank Granuloma is confirmed by a positive culture for Mycobacterium marunum. 
Co-trimoxazole tablets orally can be an effective treatment. 
He may need  anti Mycobacterial drugs like Rifampicin to cure the  disease  
Dissemination of Mycobacterium to internal organs may occur if left untreated for 1 year 
A 70 year old man with Chronic Renal Failure under peritoneal dialysis, is being treated for Cellulitis of both forearm and has not improved with 3 weeks of Intravenous Amoxcillin and Cloxacillin. Which one of the following statement is INCORRECT:
Culture of biopsied tissue may reveal Streptococcus or Mycobactium 
Mycobacterium abscesses can be the cause 
You should order a culture for Mycobacteriun leprae to rule out leprosy 
The  dialysis apparatus should be checked  for Mycobacterium hemophilium 
Clarithromycin can be used for empirical treatment.
An elderly woman sees us for an ulcer over the right ankle which has been present for 3 years. Which one of the following statements is TRUE:
Finding varicose veins confirms the diagnosis of Stasis  ulcer 
Loss of pain sensation to pin prick suggested the cause may due to leprosy 
Pseudomonas  aueruginosa isolated  with culture requires treatment with  antibiotics 
Pyoderma  gangrenosum   as the cause is confirmed by histology. 
Buruli ulcer caused by Mycobacterium ulceran is common in tropical  South East Asia 
For the  diagnosis of  Mycobacteria infection  of the skin, ONE of the following statements is TRUE: 
Culture of Mycobacterium is the most sensitive method 
T-spot and  Quenteferon test is best use for  excluding  mycobacterium tuberculosis  
Mountoux test differentiate Mycobacterium tuberculosis from Mycobacterium kansasii infection 
Polymerase Chain Reaction test is currently available to identify all species of Mycobacteria. 
Zhiel-neelson stain for acid fast Bacillus demonstrates mycobacteris for all cutaneous Tuberculosis skin diseases. 
A healthy 9 year old boy has a blood test for his application for a visa. Blood VDRL was reported as positive. The possible causes include the following, EXCEPT:
He may have  congenital syphilis 
It is unlikely to be caused by sexually  transmitted  syphilis 
A shallow scar on his shin suggest he has Yaws as the cause 
He has exchange transfusion for Neonatal jaundice  
Pinta cannot be excluded even when physical examination showed no abnormalities 
A 4 year old child has an outbreak of pustular psoriasis. In addition to the psoriatic lesion, you found rash in the perianal region. The management of the patients will include the followings, EXCEPT:
No oral antibiotic is necessary because pustular psoriasis is a sterile pustule 
Swab for culture of the perianal region to detect Streptococcus. 
Short course of oral Methotrexate for 4-6 weeks. 
Review the patient to ensure there is no relapse. 
2 weeks of daily topical Fusidic acid cream to the perianal region 
You are called to the emergency to see a 15 year old boy who is suspected to have suffered a burn injury, but the parents refuse any history of burn. Which one of the  following statements is TRUE: 
Positive Nikolsky’s sign exclude drug eruption as the cause. 
Finding  a Gram Positive cocci on Gram stain confirms  staphylococcal Scalded  skin Syndrome 
Long term anti-staphylococcal antibiotics given early, is the most important live saving measure 
You will suggest to the referring doctor to ask treat him as a burn patient  
Toxic Epidermal Necrolysis can’t be the cause since he has not taken any oral  medication 
A middle-aged woman has 4 weeks history of red subcutaneous nodules on the lower extremities, which is tender. The  following statements are true, EXCEPT: 
She has Erythema nodosum because you found out that the lesion fades as new ones develop 
All tests to exclude Tuberculosis should be done 
Prednisolone can be given after even all tests for infection turn out to be negative 
Erythema nodosum will heal with scar if it is not treated early enough 
Potassium Iodide is one of useful medicine 
An 18 year old schoolboy is referred to you for 6 episodes of furunculosis over the last 3 months. The relevant step to take in  managing  in this patient include  the  following, EXCEPT:
Culture and sensitivity test to guide you on choice of antibiotic  to be used 
Investigation  to exclude common immunocompromised  status 
Order a Toluidine blue test 
Consider prescribing  oral  Clindamycin 
Perform an Incision and Drainage 
This 60 year old woman has been treated for diabetes mellitus for 10 years. She has an abscess on the back of her neck for 2 years and it has not improved after 5 courses of antibiotics. You made a diagnosis of a Carbuncle. ONE most important step you will take is :
Incision and drainage with closure of the wound to prevent scaring. 
At least 3 weeks of antibiotics basing on culture and sensitivity. 
Male  sure  her blood sugar is  well  controlled 
Get a surgeon to open up the carbuncle  
Instruct the nurse to  dress the wound  twice a day 
A man from Germany has come to Cambodia 4 weeks ago and come to consult you for a red lesion on the abdomen and want to know whether he has Erythema Chronicum migrans. The following points in the history are relevant EXCEPT:
He has been bitten by bed-bugs 
The Erythema  is  increasing in size in a circular manner 
He has been tracking in the jungle in Germany  before coming to Cambodia 
He is allergy to the  tetracycline  group of  drugs 
Whether he has  systemic symptoms  like fever and cough 
A 30 year old soldier has lesions on both feet which are wet, partly erosive, with smell. He is otherwise healthy. The differential diagnosis include the following, Except:
Tinea  pedis   caused by a fungus 
Pitted  keratolysis  caused by  kytococcus 
Contact dermatitis to the leather boot 
Infection by Corynebacterium  stationis 
Bullous impetigo  caused by Staphylococcus
Staphylococus  aureus is a common bacteria causing infection on skin. It’s  virulence factors include the following EXCEPT: • 
Toxic Shock Syndrome Toxi n -1 causes Toxic Shock Syndrome. 
Epidermolytic  toxin A causes  bulla of  bullous  impetigo
Panton-Valentine Luecocidin (VPL) is more common in Hospital-acquired Methicillin-reisitant Staphylococcus auerus. 
VPL causes defect  in White blood cell of  human 
Superantigen is a factor in Atopic dermatitis.
A 50 year old woman was admitted for Cellulitis of the right leg. This is the 4th admission for cellulitis during the last 9 months. You also noticed that she has onychomycosis of the toe nail. The following statements regarding this patient are true,  EXCEPT: 
Escherecia coli may be the organism causing it. 
Treatment for her Onychomycosis with anti-fungal treatment need to be given immediately. 
Long term antibiotics for up to a year may be given 
Lymphactic  obstruction may  result in progressive, swelling of the leg 
She will require all investigations to exclude immunocompromised  status
The difference between Cellulitis and Erysepilas is ONE of the followings
There is lympphactic  involvement in erysepilas 
Erysepilothrix  rhuesopathia  is the organism in Erysepilas 
The bacteria can be found in fluid of erysepilas lesion but cellulitis has no bacteria. 
Histology is diagnostic for cellulitis but erysepilas shows  nonspecific  features 
Cellulitis may  be complicated  by poststreptococcal glomerulonephritis but not  erysepilas 
Necrotising Fasciitis is considered one of the dermatological emergencies. The following statements are correct EXCEPT:
Streptococcus and Staphylococcus may be the cause  and in this  case, intensive antibiotics  treatment will be sufficient  
In cases of polymicrobial  origin, surgery is needed in addition to  antibiotics 
Vibro hemolyticus  acquired from water may be a cause 
The disease can progress rapidly and result in death 
When the neck is affected (Ludwig’s angina) , tooth infection may be the source of  bacteria 
A 6 year old boy consulted for multiple rounds, erythematous and erosive plaques with Yellow crust. We found most of the lesions are around the nose and the mouth. On the body, we saw purulent blisters. The kid is otherwise healthy. Blood test shows leucocytosis and high ERS. Parents reported that 4 others classmate has the same skin lesion. What is your most likely diagnosis?
Drug eruption 
Dermatitis herpetiformis 
Allergic contact dermatitis 
Pustular psoriasis 
Impetigo contagiosa 
A 6 year old boy consulted for multiple rounds, erythematous and erosive plaques with Yellow crust. We found most of the lesions are around the nose and the mouth. On the body, we saw purulent blisters. The kid is otherwise healthy. Blood test shows leucocytosis and high ERS. Parents reported that 4 others classmate has the same skin lesion,What complication you usually would be met? Tick the WRONG answer
Healing with deep scar and keloid 
Toxic Shock Syndrome  
Staphylococcal Scalded Skin Syndrome 
Acute Glomerulonephritis 
Ecthyma
A 6 year old boy consulted for multiple rounds, erythematous and erosive plaques with Yellow crust. We found most of the lesions are around the nose and the mouth. On the body, we saw purulent blisters. The kid is otherwise healthy. Blood test shows leucocytosis and high ERS. Parents reported that 4 others classmate has the same skin lesion, What is the most useful laboratory examination you will do in 3 weeks?
CBC 
ESR 
CRP 
ASLO serology 
Liver-function 
A 6 year old boy consulted for multiple rounds, erythematous and erosive plaques with Yellow crust. We found most of the lesions are around the nose and the mouth. On the body, we saw purulent blisters. The kid is otherwise healthy. Blood test shows leucocytosis and high ERS. Parents reported that 4 others classmate has the same skin lesion, What would you advise his parents? Tick the WRONG answer:
Your son should stay away from school 
Wash your hands frequently 
Your son could not eat meat 
Wash or wipe down toys with detergent and warm water 
Don’t share flannels, sheets or towels 
A 6 year old boy consulted for multiple rounds, erythematous and erosive plaques with Yellow crust. We found most of the lesions are around the nose and the mouth. On the body, we saw purulent blisters. The kid is otherwise healthy. Blood test shows leucocytosis and high ERS. Parents reported that 4 others classmate has the same skin lesion, What antibiotic you would prescribe?
Metronidazole 
Ketokonazole 
Fluconazole 
Tetracycline 
Dicloxacilline 
The complications of untreated chlamydial cervicitis include (which answer is incorrect?):   
Salpingitis 
Infertility 
Hepatitis 
Ectopic pregnancy  
Reactive arthritis 
Trichomonas vaginalis infection (which answer is correct?):
Is more frequently symptomatic in men than in women 
Is usually confirmed by culture on Sabaurod-agar 
Can cause fever and malaise 
Requires treatment with intramuscular penicillin 
Causes often a purulent discharge with fishy odour 
A biological false positive VDRL can occur in (which answer is correct?): 
Pregnancy  
Pemphigus vulgaris  
Infectious hepatitis  
Systemic lupus erythematosus (SLE)  
Psoriasis-arthritis 
The principles of treatment of STDs include the following, (which answer is incorrect?):
Accurate diagnosis with laboratory confirmation 
Hospital admission on cases of uncertain diagnosis  
Treatment of sexual partner(s) 
Giving adequate dosage of antibiotics 
Giving adequate duration of treatmenent 
The following are recommended routine tests for people working as prostitutes (which answer is incorrect?):
Serological testing for syphilis 
Serological testing for HIV 
Serological testing for hepatitis 
Culture for Neisseria gonorrhoeae 
Culture for Mycoplasma  
The following statements are related to genital herpes, which one is correct?
A chronic bacterial infection 
A chronic viral infection 
A transient infection caused by a protozoal organism 
A transient viral infection 
A fungal infection 
One of the following statements is true for Genital herpes 
Genital herpes is a chronic infection of HPV 
Genital herpes is curable 
Genital herpes is the major clinical presentation of HSV-1 infection, but it may also result from HSV-2 
Genital herpes is the major clinical presentation of HSV-2 infection, but it may also result from HSV-1 
Genital herpes is usually transmitted from mother to child via placenta. 
The female patient comes to the STD clinic. She complains about painful genital ulcer, itching, dysuria, vaginal and urethral discharge, and tender inguinal lymphadenopathy. History taking, those lesions are started by erythematous, group of vesicles, pustules on labia minora and became ulcer. What is the most likely diagnosis:
Bacterial vaginosis  
Primary syphilis 
Chancroid 
Genital herpes 
Candidiasis vaginitis 
The following STD may lead to heart disease or insanity. Which one is the best answer?
Gonorrhea 
Syphilis 
Herpes simplex virus 
Chlamydia  
Human papilloma virus 
The response to treatment of syphilis can be assessed by:
Clinical symptoms 
TP PA titer 
RPR titer 
FTA-ABS test 
Polymerase chain reaction 
Drug of choice in secondary syphilis is :
Benzathine benzylpenicillin 
Cetriaxone 
Crystalline penicillin 
Procaine penicillin 
Doxycycline 
The clinical signs in secondary syphilis is:
Gummata of bone 
Condyloma accuminata 
Painless, hard chancre
Palmoplantar keratoderma 
Genital or oral mucous patch 
The patient comes to the STD clinic, was diagnosed as secondary syphilis and treated by 2.4 MUI benzathine benzylpenicillin for 2 months before coming to STD clinic. The laboratory investigation reveals TPPA(+), RPR(+) at 1/16. What is the appropriate treatment for this patient?
Benzathine benzylpenicillin 2.4MUI 
Doxycycline 100mg two times per day for 14 days 
Follow up until 6 months and re-assessment   
Ceftriaxone 1g/day for 2 weeks 
Culture for treponama pallidum and susceptibility 
Treatment of choice for syphilis during pregnancy is
Erythromycin 
Penicillin G 
Amoxycillin 
Cotrimoxazole 
Penicillin V
Female patient came to Dermatology department for her skin problems. Physical examination showed erythematous to coppercolored round papules, well demarcated with an annular scale, on palm and sole. She said no pain, no itch. What is your diagnosis?
Allergic contact dermatitis 
Pityriasis rubra pilaris 
Disseminated gonoccocal infection  
Secondary syphilis  
Scabies 
What is the organism which caused Lymphogranuloma Venereum?
Treponema palliduma 
Haemophilus ducreyi 
Chlamydia trachomatis  
Neisseria gonorrhoeae 
Ureaplasma urealyticum and Mycoplasma hominis 
What is the best treatment for Lymphogranuloma Venereum?
Ciprofloxacin 500mg, 1 tablet twice daily for 3 days and Doxycycline 100mg 1 tablet twice daily for 14 days  
Doxycycline 100 mg, 1tablet twice daily for 14 days,  
Azithromycin 1g once, as single dose  
Cefixime, 400 mg as a single dose 
Benzathine penicillin, 2.4 million IU IM as a single dose
The following statements are concerning HPV-infection, which one is incorrect?
Symptoms of Genital warts are sometime disappeared by good immune responses 
Genital warts can transmit one way only 
Genital warts could lead to SCC 
Treatment of genital warts is only to clear symptom  
Most of genital warts are asymptomatic
Which one of the follow diseases is rarely associated with HIV-infection?
Systemic Candidiasis 
B- Cell lymphomas  
Kaposi sarcoma 
Basal Cell Carcinoma  
Herpes zoster 
Which one is the most common pathogen found in urethritis?
Chlamydia trachomatis  
Ureaplasma urealyticum 
Streptococcus pyogenous 
Mycoplasma hominis 
Treponema palliduma 
A 30 year-old man with 59kg consulted for painful lesions on the right side of his back. He reported about losing weight of 6 kg for 6 months and about fevers 38.6 ̊C and malaise since 4 days, before the skin lesions. He took Paracetamol since the first day, but it could release fever and pain for a short time only. Redness skin lesions instead appeared on the back. Examination we found erythematous plaques, band like with clusters vesicles, partly bullae and erosion on right upper back and on the right chest. His skin otherwise looks dry.What is your likely diagnosis? Choses your best answer?
Herpes simplex 
Varicella  
Zoster  
Pemphigus vulgaris 
Drug eruption 
A 30 year-old man with 59kg consulted for painful lesions on the right side of his back. He reported about losing weight of 6 kg for 6 months and about fevers 38.6 ̊C and malaise since 4 days, before the skin lesions. He took Paracetamol since the first day, but it could release fever and pain for a short time only. Redness skin lesions instead appeared on the back. Examination we found erythematous plaques, band like with clusters vesicles, partly bullae and erosion on right upper back and on the right chest. His skin otherwise looks dry. With your diagnosis, you would like to do further physical examination on the patient, which one is the most useful
Check genital area if he has also blister  
Check conjunctiva if the patient has erosion 
Check oral mucosae for oral thrust 
Check the scalp if the patient has also blister 
Check the peri-umbilical area if the patient has erosion 
A 30 year-old man with 59kg consulted for painful lesions on the right side of his back. He reported about losing weight of 6 kg for 6 months and about fevers 38.6 ̊C and malaise since 4 days, before the skin lesions. He took Paracetamol since the first day, but it could release fever and pain for a short time only. Redness skin lesions instead appeared on the back. Examination we found erythematous plaques, band like with clusters vesicles, partly bullae and erosion on right upper back and on the right chest. His skin otherwise looks dry. What would be the most useful test you would do?
Total IgE  
Skin prick test 
Skin patch test 
HIV test 
Liver function test  
A 30 year-old man with 59kg consulted for painful lesions on the right side of his back. He reported about losing weight of 6 kg for 6 months and about fevers 38.6 ̊C and malaise since 4 days, before the skin lesions. He took Paracetamol since the first day, but it could release fever and pain for a short time only. Redness skin lesions instead appeared on the back. Examination we found erythematous plaques, band like with clusters vesicles, partly bullae and erosion on right upper back and on the right chest. His skin otherwise looks dry. What is your most concern?
Damage to liver-function  
Damage to kidney-function  
Prolong pain or paresthesia of the skin lesion 
Recurrent of skin lesions 
Other people (contacted people) may get the same disease   
A 30 year-old man with 59kg consulted for painful lesions on the right side of his back. He reported about losing weight of 6 kg for 6 months and about fevers 38.6 ̊C and malaise since 4 days, before the skin lesions. He took Paracetamol since the first day, but it could release fever and pain for a short time only. Redness skin lesions instead appeared on the back. Examination we found erythematous plaques, band like with clusters vesicles, partly bullae and erosion on right upper back and on the right chest. His skin otherwise looks dry. What is your treatment?
Oral steroid 1mg/kgBW with antihistamine 
Topical steroid (clobetasole) apply BID and Oral antihistamine 
Oral steroid 1mg/kgBW and paracetamol 
Topical steroid (clobetasole) and oral antibiotic (cloxacilline 500mg TID) 
Oral Aciclovir 800mg every 4 hours, paracetamol 500mg every 6 hours and Cloxacilline 500mg TID
Leprosy is a disease caused by (tick correct answer)  
 a virus  
A protozoon  
A bacteria  
A fungus  
A parasite
Leprosy is transmitted most likely by (tick correct answer)
Skin-contact 
Respiratory secretions  
Feces 
Uro-genital secretions  
By trans-placentar infection 
Incubation period for leprosy is (tick correct answer)
3 to 5 days  
3 to 5 months  
3 to 5 years  
7 to 10 years  
More than 10 years 
In leprosy, cellular immunity is 0 and stable in (tick correct answer)
TT  
BT  
BB 
D BL  
LL
A diagnosis of leprosy is based on (tick correct answer)
A hypopigmented scaly macule  
A hypopigmented anesthetic plaque  
A pustular plaque  
A group of vesicles  
A hyperpigmented nodule 
The germs causing leprosy divide every (tick correct answer)
24 minutes  
24 hours 
7 days  
14 days  
21 days 
Treatment duration in PB leprosy is (tick correct answer)
3 months  
6 months
9 months  
12 months  
24 months 
Type II reaction (ENL, erythema nodosum leprosum) is immunologically a (tick correct answer) 
Type I reaction  
Type II reaction  
Type III reaction  
Type IV reaction  
Type V reaction 
In leprosy, a plaque with well demarcated border is characteristic for (tick correct answer)
TT  
BT  
BB  
BL  
LL 
MDT for MB leprosy according to WHO protocol consists of (tick correct answer)
Rifampicine / dapsone / ofloxacine  
Rifampicine / dapsone / minocycline  
Clofazimine/ dapsone / ofloxacine 
Clofazimine/ dapsone / rifampicine 
Clofazimine/ rifampicine / ofloxacine 
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