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Neuroscience and Pharmacology Quiz
Test your knowledge on essential topics in neuroscience and pharmacology. This quiz includes a variety of questions covering crucial aspects of the human brain, neurological disorders, and the medications associated with them.
Whether you are a student, a teacher, or someone interested in neuroscience, challenge yourself with these engaging questions!
- 42 questions on neuroscience and pharmacology
- Multiple choice and text answer formats
- Ideal for students and professionals alike
Which of these bones does NOT contribute to the bony orbit?
Zygomatic
Nasal
Palatine
Ethmoid
Sphenoid
Which of these is the correct order of cells in the retina, from outermost layer to innermost layer?
Retinal Pigmented layer, photoreceptors (rods+cones), retinal ganglion cells, bipolar cells
Photoreceptors (rods+cones), Bipolar cells, retinal ganglion cells, retinal pigmented layer
Photoreceptors (rods +cones), retinal pigmented layer, bipolar cells, retinal ganglion cells
Retinal pigmented layer, photoreceptors (rods+cones), bipolar cells, retinal ganglion cells
Photoreceptors, retinal ganglion cells, retinal pigmented layer, bipolar cells
Open angled glaucoma is caused by increase resistance in which part of the eye?
Canal of Schlemm
Trabeculae Meshwork
Iris
Ciliary body
Cornea
Which of these is an example of a positive symptom of schizophrenia?
Alogia
Memory Loss
Delusions
Disinterest
Avolition
Which combination of symptoms could lead to a diagnosis of schizophrenia?
Hallucinations + Tremor
Delusions + Disorganised behaviour
Alogia + Avolition
Disorganised behaviour + Memory loss
Memory loss + flat affect
Which of these pathways is involved in addictive behaviour?
Mesocortical
Mesolimbic
Nigrostriatal
Tuberoinfundibular
Which of these pathways is downregulated in schizophrenia?
Mesocortical
Mesolimbic
Nigrostriatal
Tuberoinfudibular
A patient experiences sexual dysfunction whilst taking haloperidol, the blockage of D2 receptors in which of these pathways is most likely responsible for this sideeffect?
Mesocortical
Mesolimbic
Nigrostriatal
Tuberoinfundibular
Atypical antipsychotics aim to target the D2 and which other receptor?
D1
D3
5-HT2a
5-HT2b
5-HT3
A patient comes in pyretic and febrile, a FBC is done and it is noted that she has a significantly lowered neutrophil count, which one of these drugs is most likely to be responsible for the patients condition?
Olanzapine
Clozapine
Risperidone
Aripiprazole
Haliperidol
Which anti-depressant medication causes anti-cholinergic side effects?
Citalopram
Venlafaxine
Amitriptyline
Phenelzine
Bupropion
A patient comes in with flailing arm movements. In the patient notes it says this patient has tested positive for a mutation on the HTT gene. Given the likely diagnosis which structure in the brain is likely the most damaged?
Pre-central gyrus
Striatum
Internal globus pallidus
Sub thalamic nucleus
Substantia nigra pars compacta
Which one of these structures is involved in only the indirect pathway of the basal ganglia?
Striatum
Thalamus
Globus pallidus externa
Globus pallidus interna
Subthalamic nucleus
In the basal ganglia, when the D1 receptor is stimulated it:
Excites the inhibitory neurons in the striatum
Excites the excitatory neurons in the striatum
Inhibits the inhibitory neurons in the striatum
Inhibits the excitatory neurons in the striatum
Which drug combination would most effectively prevent the breakdown of L-dopa in the peripheral system??
Carbidopa + Benserazide
Selegeline + Tolcapone
Benserazide + Entacapone
Rotigotine + Selegeline
Bromocryptine + carbidopa
A patient loses consciousness falls to the fall suddenly and begins spasmodically jerking. They have been doing so for only a minute. What is the first line treatment for the likely diagnosis?
Phenytoin
Sodium valproate
Lamotrigine
Carbamazepine
Diazepam
Which of the following statements is correct? (format: drug - target - notable side effect)
Sodium valproate - postsynaptic sodium channel blocker + prevents GABA breakdown- teratogenic
Carbamazepine - presynaptic calcium channel blocker - agranulocytosis
Lamotrogine - presynaptic calcium channel blocker - aplastic anaemia
Lorazepam - potentiates GABA at post synaptic chlorine channels - respiratory depression
Phenytoin - stimulates postsynaptic chlorine channels - folate deficiency
AA patients' partner tells you that mid-conversation the patient exclaimed they were 'having deja vu' before getting up and putting their shoe in the toaster - during this time the patient was described to have been 'on auto-pilot'. Their partner knew this was a sign of a seizure and brought them into the ED. In which region of the brain does the most likely type of seizure originate from?
Frontal lobe
Parietal lobe
Temporal lobe
Occipital lobe
Cerebellum
Wernicke-Korsakoff syndrome irreversibly effects which part of the limbic system?
Hippocampus
Cingulate gyrus
Amygdala
Mammillary bodies
Nucleus accumbens
A patient suffers from aphasia. Their speech is fluent and coherent but when asked to repeat words or phrases they begin to struggle. Where is the lesion in the brain?
Wernickes area
Brocas area
Arcuate fasciculus
Wernickes area on the right hand sign
Cerebellum
A patient suffers from aphasia. Their speech is fluent but incoherent. Where is the brain lesion?
Wernickes area
Brocas area
Arcuate fasiculus
Brocas area on the right hand side
Cerebellum
A patient suffers from aphasia after a stroke. Their speech is fluent and coherent but it contains no tone and sounds robotic. In which artery was the stroke?
Left ACA
Right ACA
Left MCA
Right PCA
Right MCA
Left PCA
A patient has a blood clot form in their posterior spinal artery at the T7 level, describe the deficits the patient would exhibit.
Which spinal tract is responsible for ipsilateral voluntary movement?
Anterior corticospinal
Lateral corticospinal
Lateral reticulospinal
Medial reticulospinal
Vestibulospinal
Which of these signs and symptoms are not associated with a cerebellar injury?
Truncal ataxia
Nystagmus
Resting tremor
Dysdiadochokinesia
Slurred speech
A patient suffers a stroke and loses feeling of their left leg. Which artery was the stroke in?
Left ACA
Right ACA
Left MCA
Right MCA
Left PCA
Right PCA
Which foramen does the mandibular nerve pass through?
Superior orbital fissure
Foramen spinosum
Foramen rotundum
Foramen ovale
Mental foramen
Which intercranial bleed is contained by the cranial sutures?
Epidural
Subdural
Subarachnoid
Intracranial
Interdural
A transient ischemic attack is defined as neurological dysfunction secondary to ischaemia without infarction. What is the management of a TIA?
Just observation & lifestyle advice
Low molecular weight heparin & clopidogril & lifestyle advice
300mg aspirin daily & secondary CVD prevention & referral to a specialist
300mg aspirin daily & secondary prevention of CVD & lifestyle advice
300mg aspirin daily & observation
Which of these is not a risk factor for strokes?
Hypertension
Diabetes
Smoking
Combined contraceptive pill
Being Caucasian
Which of these muscles would be spared in a trigeminal nerve lesion?
Temporalis
Medial pterygoid
Buccinator
Lateral pterygoid
Masseter
Which of these genes aren't related to Alzheimer's disease?
APoEe4
Presenilin 1
Presenilin 2
TP53
APP gene
What is the method of action of memantine?
NMDA receptor antagonist
NMDA receptor agonist
Sodium channel blocker
Glutamate analogue
GABA analogue
A 27yo female patient comes in complaining of an intense shooting pain around their left cheek, their last menstrual period was 4 weeks ago, what is the likely cause?
Tension headache
Trigeminal neuralgia
Hormonal headache
Sinusitis
Migraine
Sumatriptan is a migraine medication. What is its mechanism of action?
Dopamine analogue
Prevents reuptake of norepinephrine and serotonin
Serotonin receptor agonist
5-HT receptor antagonist
Anti-emetic
Which part of the vestibular system is responsible for detecting horizontal displacement of the head?
Anterior semi-circular canal
Posterior semi-circular canal
Lateral semi-circular canal
Utricle
Saccule
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