Elyrolyte
A 22-year-old female is hospitalized after a car accident. She sustained a hip fracture, fractures of several ribs and a blunt abdominal injury that required a laparotomy. The laparotomy revealed a liver laceration and extensive hemoperitoneum. In the early postoperative period, the patient is noted to have hyperactive deep tendon reflexes. Which of the following electrolyte abnormalities may be responsible for this condition?
. Hypokalemia
. Hyperkalemia
. Hyponatremia
. Hypocalcemia
. Hypermagnesemia
A 27-year-old woman presents to the emergency room with a panic attack. She appears healthy except for tachycardia and a respiratory rate of 30. Electrolytes include calcium 10.0 mg/dL, albumin 4.0 g/dL, phosphorus 0.8 mg/dL, and magnesium 1.5 mEq/L. Arterial blood gases include pH of 7.56, PCO2 21 mm Hg, and PO2 99 mm Hg. Which of the following is the most likely cause of the hypophosphatemia?
. Hypomagnesemia
. Hyperparathyroidism
. Respiratory alkalosis with intracellular shift
. Poor dietary intake
. Vitamin D deficiency
A 23-year-old woman is brought to the emergency room from a halfway house, where she apparently swallowed a handful of pills. The patient complains of shortness of breath and tinnitus, but refuses to identify the pills she ingested. Pertinent laboratory values are as follows:Arterial blood gases: pH 7.45, PCO2 12 mm Hg, PO2 126 mm Hg.Serum electrolytes (mEq/L): Na+ 138, K+ 4.8, Cl− 102, HCO3− 8.An overdose of which of the following drugs would be most likely to cause the acid–base disturbance in this patient?
. Phenformin
. Aspirin
. Barbiturates
. Methanol
. Diazepam (Valium)
A 28-year-old primigravida is admitted to the hospital at 10weeks gestation. Her right leg is swollen. Her BMI is 30 Kg/m2. Her temperature is 36.7°C (98.2°F), respirations are 12/min and pulse is 96/min. Her ABG shows the following: pH 7.49, PaCO2 50 mm Hg, HCO3- 44 mEq/L. Which of the following is the most likely cause of her abnormal arterial blood gas?
. Normal phenomenon of pregnancy
. Pulmonary embolism
. Obesity
. Aspiration pneumonitis
. Hyperemesis gravidarum
A 3-week-old African American boy is brought to the Emergency Department because of a generalized seizure 2 hours ago. The infant is highly irritable with incessant high pitched crying. The infant's weight is 2.5 kg (250 gm below birth weight), blood pressure is 70 /40 mm Hg, pulse is 145/min and respirations are 50/min. Laboratory results show: Blood glucose 120 mg/dL, Urea nitrogen 50 mg/dL, Serum sodium 170 mEq/L, Serum calcium 8.5 mg/dL, Serum magnesium 1.5 mg/dL. Which of the following is the most likely cause of this infant’s seizure?
. Hypocalcemia
. Hypoglycemia
. Hypomagnesemia
. Intracranial hemorrhage
. Meningitis
) A 3-year-old boy is brought to the emergency department three hours after having a seizure. He has been having severe diarrhea for the last three days. His mother recently read about the importance of maintaining adequate hydration during diarrhea, so she had been giving him a lot of milk mixed with water. On examination, his vital signs are stable and mucus membranes are moist. Initial lab results are: Hb 13 g/dl, WBC 6,000/mm3, Platelets 300,000/mm3, Blood Glucose 98 mg/dl, Serum Na 120 mEq/L, Serum K 3.4 mEq/L, Chloride 92 mEq/L, BUN 22 mg/dl, Creatinine 1.2 mg/dl. What is the most likely cause of this patient's seizure?
SIADH
Water intoxication
Severe dehydration
Acute renal failure
Sepsis
A 32-year-old male with type 1 diabetes and severe depression is brought to the emergency department because of a 2-day history of nausea and abdominal pain. His temperature is 37.6°C (99.7°F), blood pressure is 122/86 mmHg, respirations are 25/min and pulse is 88/min. His lab values are as follows: Blood pH 7.31, PaO2 90mm Hg, PaCO2 29 mmHg, HCO3- 14 mEq/L, Blood glucose 450 mg/dl, Serum sodium 132 mEq/L, Serum potassium 5.0 mEq/L, Serum chloride 85mEq/L, Blood urea nitrogen 19 mg/dl, Serum creatinine 1.1 mg/dl. Which of the following best describes this patient's acid-base status?
. Primary metabolic acidosis with respiratory compensation
. Respiratory acidosis with compensation
. Primary metabolic acidosis without compensation
. Primary metabolic alkalosis with renal compensation
. Normal acid base status
A 32-year-old pregnant female is being evaluated at her 32nd week of gestation. Her lab profile shows the following: Blood pH 7.44, PaO2 100 mmHg, PaCO2 30 mmHg, HCO3- 20 mEq/L, WBC count 9,000/cmm, Hb 11 mg/dl, Na+ 134 mEq/L, K+ 3.6 mEq/1, Cl- 98 mEq/L, BUN 5 mg/dlCreatinine 0.6 mg/dl. Which of the following can best explain her acid-base status?
. Anemia
. Pulmonary embolism
. Obesity
. Normal phenomenon of pregnancy
. Hyperemesis gravidarum
A 34-year-old man is brought to the emergency department after being involved in a motorbike accident. Examination shows a hematoma on the forehead and bleeding from his leg. His pupils are bilateral round and eactive; he has papilledema. He responds to pain, has decorticated posture and speaks incoherently. After the initial resuscitation you start the treatment with intravenous fluids, hyperventilation, head elevation and intravenous mannitol. Which of the following is the mechanism of action of hyperventilation in this patient?
. Hyperventilation acts as stimuli to brain and helps to arouse the patient
. Hyperventilation corrects hypoxia
. Hyperventilation helps to wash out the carbon dioxide
. Hyperventilation causes vasoconstriction and helps to reduce his bleeding
. Hyperventilation causes vasoconstriction and thus decreases the cerebral blood flow
A 44-year-old obese female undergoes an open cholecystectomy for a complicated acute cholecystitis. On her third post-operative day, her temperature is 36.7°C (98.2°F), blood pressure is 110/80 mm Hg and pulse is 92/min. Her arterial blood gas shows the following: Blood pH 7.28, PaO2 62 mmHg, PaCO2 54 mmHg, HCO3- 30 mEq/L. What is the most likely cause of acidosis in this patient?
. Alveolar hypoventilation
. Acute pulmonary embolism
. Atelectasis
. Pulmonary edema
. Pleural effusion
A 45-year-old woman with Crohn disease and a small intestinal fistula develops tetany during the second week of parenteral nutrition. The laboratory findings include: Na: 135 mEq/LK: 3.2 mEq/LCl: 103 mEq/LHCO3: 25 mEq/LCa: 8.2 mEq/LMg: 1.2 mEq/LPO4: 2.4 mEq/LAlbumin: 2.4An arterial blood gas sample reveals a pH of 7.42, PCO2 of 38 mm Hg, and PO2 of 84 mm Hg. Which of the following is the most likely cause of the patient’s tetany?
. Hypocalcemia
. Hyperventilation
. Hypomagnesemia
. Essential fatty acid deficiency
. Focal seizure
A 52-year-old alcoholic man presents to the emergency department because of anxiety and tremors. His last drink of alcohol was 2 days ago. His initial electrolyte panel is: Sodium 132 mEq/L, Potassium 2.9 mEq/L, Chloride 100 mEq/L, Bicarbonate 25 mEq/L. He is treated for alcohol withdrawal, and given aggressive intravenous and oral potassium supplementation. Three days later, his electrolyte panel is: Sodium 135 mEq/L, Potassium 3.1 mEq/L, Chloride 102 mEq/L, Bicarbonate 28 mEq/L. Which of the following explains why this patient's potassium level is so difficult to correct?
. Poor oral absorption
. Hypophosphatemia
. Alcohol withdrawal
. Hypomagnesemia
. Thiamine deficiency
A 55-year-old woman has been hospitalized because of recurrent pancreatitis, ARDS, prolonged ileus, and need for parenteral nutrition. She demonstrates weakness, lassitude, orthostatic hypotension, nausea, and fever. Which of the following abnormalities is most likely to explain these symptoms?
. Hypothermia
. Hypokalemia
. Hyperglycemia
. Hyponatremia
. Hypervolemia
A 54-year-old woman presents to your office complaining of difficulty walking. She describes severe weakness and occasional pain in her thigh muscles. She has stumbled and fallen several times over the last week. Her past medical history is significant for hypertension treated with hydrochlorothiazide and metoprolol. She consumes two to three cans of beer on weekends. Her younger brother died of a neurological disease when he was 20 years old. Her mother suffers from hypertension and diabetes mellitus. Her heart rate is 90/min and blood pressure is 170/100 mmHg. Chest examination is within normal limits. A bruit is heard over the left carotid artery. Neurologic examination reveals hyporeflexia and decreased strength in all muscle groups. Her ESR is 12 mm/hr. ECG shows flat and broad T waves with occasional premature ventricular contractions. Which of the following is the most likely cause of this patient's current complaints?
. Ischemic stroke
. Epidural hematoma
. Subdural hematoma
. Lumbar spinal stenosis
. Electrolyte disturbance
A 52-year-old male is referred to the neurology clinic for the evaluation of EEG abnormalities. He presented with rapidly increasing memory impairment, and denied any history of seizures or head trauma. The physical examination revealed no abnormalities, except a myoclonus. An extensive work-up ruled out the presence of any medical illness; however, the EEG report revealed sharp, triphasic and synchronous discharges. Which of the following abnormalities is most likely in this patient?
. Defect in an autosomal dominant gene on chromosome 4
. Spongiform encephalopathy caused by a prion
. Loss of nigrostriatal dopaminergic neurons
. Histopathological findings of neurofibrillary tangles and amyloid plaques
. Neurodegeneration of frontal and temporal lobes
A 60-year-old woman with heart failure and normal renal function is started on furosemide (Lasix) 80 mg/day. She notices a good diuretic response every time she takes the medication. A few weeks later, she is feeling unwell because of fatigue and muscle weakness, but her heart failure symptoms are better. Which of the following is the most likely explanation for her muscle weakness?
hyponatremia
hypernatremia
Hypokalemia
Hyperkalemia
Anemia
A 62-year-old man has progressive symptoms of dyspnea, and more recently noticed difficulty lying supine. Examination shows an elevated JVP at 8 cm, with a third heart sound, pedal edema, and bibasilar crackles on auscultation. Which one of the following may be implicated in fluid retention for this condition?
decreased renin
increased estrogen
increased aldosterone
increased growth hormone
decreased vasopressin
A 64-year-old man presents to the emergency department with progressive exertional dyspnea that worsened after he contracted an upper respiratory infection. He also complains of bilateral ankle swelling. He has a 40 pack-year history of smoking. Physical examination reveals a mildly overweight patient in mild respiratory distress. Lung auscultation reveals bilateral wheezes and a prolonged expiratory phase. His white blood cell count is 14,500/mm3 and his hemoglobin level is 16 mg/dl. Arterial blood gas analysis reveals the following: pH 7.37, pO2 65mmHg, pCO2 60mmHg. Absence of marked acidosis in this patient is best explained by which of the following
. Increased minute ventilation
. Increased dead space ventilation
. Pulmonary vasoconstriction
. Renal tubular compensation
. Erythrocyte chloride shift
) A 71-year-old man is brought to the ER after a witnessed tonic-clonic seizure. He is somnolent and intermittently combative on exam. No past medical history is available. His arterial blood gas (ABG) at room air is given below: pH 7.23, pCO2 69 mmHg, pO2 57 mmHg, HCO3 28 mmHg. Which of the following best explains the acid-base disturbances in this patient?
. Lactic acid accumulation
. Hypoventilation
. Pulmonary embolism
. Renal failure
. Protracted vomiting
A 73-year-old Caucasian man is brought to the office by his daughter, who is concerned that he might be depressed. He is a retired surgeon, and has lived alone ever since his wife died a year ago. His daughter visits him every 6 months; she feels bad about not being able to visit him more frequently because her job and family keep her very busy. He denies having any feelings of sadness, guilt, weight loss, loss of appetite, suicidal ideation, deafness, vertigo, and decreased or blurred vision. His medical problems include hypertension, diabetes mellitus-type 2 and a myocardial infarction 10 years ago. His current medications are glyburide, aspirin and enalapril. He denies the use of tobacco, alcohol, or drugs. His vital signs are within normal limits. He appears withdrawn, less energetic than usual, and walks stiffly. He sits with a stooped posture. He has a fixed facial expression, and his voice sounds monotonous. His deep tendon reflexes are 2+. Sensations and motor strength are normal. There is increased resistance to passive flexion. Which of the following types of gait is most likely to be present in this patient?
. Cerebellar ataxia
. Hypokinetic gait
. Waddling gait
. Spastic gait
. Gait disequilibrium
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