ChPN-NK92

An artistic illustration of NK cells interacting with tumor cells, showcasing molecular structures, fluorescence, and immunotherapy concepts in a vibrant and educational style.

Understanding NK Cells and Chimeric Proteins

Test your knowledge on the fascinating world of NK cells and their interactions with cancer cells through our engaging quiz!

Throughout the quiz, you'll explore important concepts such as:

Functions of hinge domains and linkers
Role of 4-1BB in immunotherapy
Functionality of PLNBB-NK92 cells

5 Questions1 MinutesCreated by InvestigatingCell23

Do hinge domain and linkers play the same function?

Yes, they both link multi-domain proteins

No, they have different functions

What are the functions of 4-1BB?

To improve the proliferation and persistence of NK cells.

To improve the stability of chimeric proteins

Both

Why PLNBB-NK92 cells does not exhibit the enhanced green fluroscence?

Because the authors didn't construct PLNBB receptor successfully.

Because the EGFP gene was replaced by DAP10 in PLNBB.

PNBB-NK92 cells are able to specifically kill tumor cells with PD-L1 expression by secreting cytokines and cytotoxic molecules.

True

False

Do you think there is any solution for increasing the NKG2D backbone stability?

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