Embryology Practice Exam 3
Embryology Practice Exam 3
Test your knowledge on embryology with our comprehensive 40-question practice exam. This quiz covers key concepts across various model organisms, including C. elegans, Drosophila melanogaster, and Xenopus tropicalis, focusing on developmental processes and molecular signaling pathways.
Whether you're a student preparing for exams or a teacher assessing understanding, this quiz offers:
- Challenging questions
- A variety of topics within embryology
- Immediate feedback on your performance
Which of the following classifications has bilateral symmetry?
Metazoan
Triploblasts
Diploblasts
Lophotrochozoans
In Lophotrochozoans, how do mRNA localize to one of the two centrosomes in each micromere quadrant?
Epiboly
Leading edge cells
3’ UTR mRNA sequence
WNT signaling cascade
Maternal Effect Genes
C. Elegans are excellent model systems for all of the reasons EXCEPT
Small genome
Good for mutagenesis screening
Few cell types
Good for locating genes on chromosomes
Which of the following describes the anterior side of C. Elegans embryo?
AB cell, which is autonomous
AB cell, which is conditional
P cell, which is autonomous
P cell, which is conditional
In the C. Elegans embryo, after the sperm centrosome enters, which proteins are localized to the anterior end of the cell?
PAR-1 and PAR-2
PAR-2 and PAR-6
PAR-1 and PAR-3
PAR-3 and PAR-6
Which of the following species were used as model systems to discover caspases, miRNA, and RNAi?
C. elegans
Drosophila Melanogaster
Xenopus Tropicalis
Tyrannosaurus Rex
2n = 8 means what?
A haploid cell has 8 chromosomes
A diploid cell has 4 chromosomes
A haploid cell has 4 chromosomes
A diploid cell has 16 chromosomes
Drosophila Melanogaster are excellent model systems for all of the reasons EXCEPT
24 hour embryogenesis
Hundreds of eggs per female
Small genome
2 week generation time
For Drosophila, at what nuclear division in the syncytium does cellularization occur in the superficial cleavage?
Round 10
Round 9
Round 12
Round 13
Which of the following processes does NOT occur in the Drosophila development before nuclear division round 11?
Translation
Transcription
Pole cells are formed
Mitotic divisions occur every 8 minutes
Which of the following parts of the Drosophila embryo becomes the mesoderm during gastrulation?
Anterior/posterior ends
Cephalic furrow
Germ band
Ventral furrow
Pole cells
Which of the following parts of the Drosophila thorax form only legs?
T1
T2
T3
T4
In Drosophila, which of the following transcription factors do NOT express segmentation genes?
Hunchback
Nanos
Caudal
Goosecoid
Bicoid
In Drosophila, Gap gene mutants that have no Giant are most likely to have which of the following?
High levels of Hunchback
High levels of Caudal
High levels of Kruppel
High levels of Giant
A mutation in which homeotic selector genes of the Hom-c complex is likely to cause Drosophila to have legs where their antennae should be?
Antennapedia
Bithorax
Ultrabithorax
Head
How does the protein Dorsal function after it is released by cactus in Drosophila?
Enters nucleus on dorsal side and causes dorsal identity
Enters nucleus on anterior side and causes posterior identity
Enters nucleus on posterior side and causes anterior identity
Enters nucleus on ventral side and causes ventral identity
Which of the following is a defect caused by homozygous mutants of Nanos3?
Cerebellum Anomalies
Male and female infertility
3rd & 4th cranial nerve anomalies
Skeletal anomalies
Which of the following cells in C. Elegans development has activated Notch signaling (Hint: it also represses pharynx formation)
EMS cell
P2 cell
ABp cell
ABa cell
Xenopus Tropicalis are excellent model systems for all the reasons EXCEPT
They are vertebrates
External fertilization with lots of embryos
Large and easily manipulated embryos
Rapid Development
Small size
In Xenopus, what function does the sperm centriole perform during cortical rotation?
Rotates the cell 30 degrees
Organizes egg microtubules to separate cortical cytoplasm from gray crescent
Degrades to feed the egg yolk vital nutrients
Forms the cleavage furrow
Which of the following forms the ectoderm in Xenopus?
Animal pole
Vegetal blastomeres
Region between blastocoel floor and blastopore lip
Vegetal pole
Which of the five behaviors necessary for gastrulation uses radial intercalation to spread animal cap cells over the vegetal hemisphere?
Epiboly
Vegetal rotation
Bottle cell formation and invagination
Involution and cell migration
Convergence and extension
Which of the five behaviors necessary for gastrulation causes vegetal cells in the blastocoel floor to press against the blastopore roof in gray crescent to migrate endoderm cells along the blastocoel roof?
Epiboly
Vegetal rotation
Bottle cell formation and invagination
Involution and cell migration
Convergence and extension
Which of the five behaviors necessary for gastrulation causes epithelial cells to change shape so that the main cell body is inside the embryo but still has contact with the outside. (Hint: it also generates the dorsal blastopore lip)
Epiboly
Vegetal rotation
Bottle cell formation and invagination
Involution and cell migration
Convergence and extension
Which of the five behaviors necessary for gastrulation causes a tissue to turn inward, spread over blastocoel roof to generate IMZ, and forms bilateral lips that become the yolk plug from the blastopore lip.
Epiboly
Vegetal rotation
Bottle cell formation and invagination
Involution and cell migration
Convergence and extension
What separates the mesendoderm from the ectoderm in the blastocoel roof?
Bottle cells
Brachet’s cleft
The organizer
Prechordal plate
When leading edge cells crawl along fibronectin to perform cell migration and form the endomesoderm, which protein complexes allow them to withstand stress?
Hunchback and Caudal
Giant and Kruppel
Bicoid and Nanos
Cadherin and Keratin
Which of the five behaviors necessary for gastrulation causes movements that narrow and elongate tissue along the anterior to posterior axis using WNT signaling.
Epiboly
Vegetal rotation
Bottle cell formation and invagination
Involution and cell migration
Convergence and extension
WNT signaling is particularly dependent on what?
Cadherin
Keratin
Disheveled
Bicoid
Which region of the mesendoderm becomes the prechordal plate?
Vegetal cells that begin rotation
First cells to involute
Chordamesoderm
Pharyngeal endoderm
Which transcription factor in the mesendoderm is used for the chordamesoderm?
Hhex
Goosecoid
Xbra
Disheveled
Which of the following is true about the effects of VegT during germ layer specification?
Uses Sox17 to form endoderm, which is autonomously specified
Uses Sox17 to form mesoderm, which is autonomously specified
Uses Nodal to form mesoderm, which is autonomously specified
Uses Nodal to form endoderm, which is conditionally specified
In the formation of the organizer, B-catenin is moved to the gray crescent side of the embryo, which of the following is NOT involved in IMMEDIATE prevention of B-catenin degradation?
DSH
WNT11
GBP
TCF
Which of the following occurs in Xenopus mesoderm when there are high amounts of Nodal?
Kidney formation
Notochord formation
Secondary axis formation
Archenteron formation
Which of the following occurs when the organizer does not inhibit BMP signaling?
Epidermis forms
Neural tube forms
Lateral plate mesoderm forms
Axial mesoderm forms
Which of the following is a function of transporting the blastopore lip from late gastrula into the blastocoel?
Forms anterior structures
Forms posterior structures
Forms dorsal structures
Forms ventral structures
What causes Zebrafish cleavage divisions to be meroblastic?
Noggin
Chordin
Follistatin
Blastodisc
What are the mound of cells on top of yolk called in Zebrafish?
Yolk plug
Blastocoel
Posterior axis
Blastopore
What is the fate of cells that involute in Zebrafish development?
Form hypoblast, which forms ectoderm
Form hypoblast, which forms mesendoderm
Form epiblast, which forms ectoderm
Form epiblast, which forms mesendoderm
What is the difference between the organizer and the embryonic shield?
Embryonic shield forms chordamesoderm, organizer does not
Transplantation of embryonic shield does not induce secondary axis
While noggin and chordin are expressed in both, goosecoid is expressed in organizer and follistatin is expressed in embryonic shield
No difference, go fuck yourself
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