Gyn Management P1 Q 151 to 200
151) A 21-year-old primigravid woman at 39 weeks' gestation comes to the labor and delivery ward with painful contractions every three minutes. Her prenatal course was unremarkable. Examination shows her cervix to be 3 centimeters dilated and 90% effaced. The fetal heart rate tracing is in the 150s and reactive. 5 hours later cervical examination reveals that the patient is 9 centimeters dilated and at -1 station. The fetal heart rate tracing shows moderate variable decelerations with each contraction and decreased variability. Fetal scalp sampling is performed that yields fetal scalp pH of 7.04, 7.05, and 7.06. Which of the following is the most appropriate next step in management?
. Expectant management
. Episiotomy
. Forceps-assisted vaginal delivery
. Vacuum-assisted vaginal delivery
. Cesarean delivery
152) A 31-year-old, HIV-positive woman, gravida 3, para 2, at 32-weeks' gestation comes to the physician for a prenatal visit. Her prenatal course is significant for the fact that she has taken zidovudine throughout the pregnancy. Otherwise, her prenatal course has been unremarkable. She has no history of mental illness. She states that she has been weighing the benefits and risks of cesarean delivery in preventing transmission of the virus to her baby. After much deliberation, she has decided that she does not want a cesarean delivery and would like to attempt a vaginal delivery. Which of the following is the most appropriate next step in management?
. Contact psychiatry to evaluate the patient
. Contact the hospital lawyers to get a court order for cesarean delivery
. Perform cesarean delivery at 38 weeks
. Perform cesarean delivery once the patient is in labor
. Respect the patient's decision and perform the vaginal delivery
153) An 18-year-old woman comes to the physician for advice regarding birth control. She has been sexually active since the age of 15 and has had numerous sexual partners since that time. She has tried the oral contraceptive pill twice, for approximately two cycles each time, but stopped because of irregular bleeding. She has had gonorrhea once and Chlamydia twice. She does not smoke. Physical examination is unremarkable. Which of the following forms of birth control should be recommended for this patient?
. Condoms
. Diaphragm
. Intrauterine device
. Oral contraceptive pill
. Tubal ligation
154) A pharmaceutical company sponsors a physician lecture concerning thrombotic complications of the oral contraceptive pill (OCP). At the start of the presentation, the company's representative makes a short presentation regarding their particular brand of OCP. He then proceeds to announce that his company would like to award a gift to the physician in the group who gives the largest number of prescriptions for this pill. Which of the following is the most appropriate action?
. Acceptance of the gift
. Attempt to get colleagues to prescribe the medication
. Promise to prescribe more of the medication
. Refusal of the gift
. Request for money rather than a gift
155) A 24-year old woman comes to the physician because of burning with urination. She states that every time she urinates there is pain and that she has a feeling that she constantly needs to urinate even though only a little comes out. She has never had any similar symptoms before. She has no medical problems and no known drug allergies. Examination is unremarkable. Urinalysis demonstrates that the urine is positive for leukocyte esterase and nitrites. Which of the following is the most appropriate pharmacotherapy?
. Intramuscular ceftriaxone
. Intravenous levofloxacin
. Oral levofloxacin for 7 days
. Oral trimethoprim-sulfamethoxazole for 3 days
. Wait for the culture results to institute therapy
156) An 18-year-old G2P1 presents to the emergency department with abdominal pain and vaginal bleeding for the past day. Her last menstrual period was 7 weeks ago. On examination she is afebrile with normal blood pressure and pulse. Her abdomen is tender in the left lower quadrant with voluntary guarding. On pelvic examination, she has a small anteverted uterus, no adnexal masses, mild left adnexal tenderness, and mild cervical motion tenderness. Labs reveal a normal white count, hemoglobin of 10.5, and a quantitative β-hCG of 2342. Ultrasound reveals a 10×5×6 cm uterus with a normal-appearing 1-cm stripe and no gestation sac or fetal pole. A 2.8-cm complex adnexal mass is noted on the left. In the treatment of this patient, laparoscopic salpingostomy has what advantage over salpingectomy via laparotomy?
. Decreased hospital stays
. Lower fertility rate
. Lower repeat ectopic pregnancy rate
. Comparable persistent ectopic tissue rate
. Greater scar formation
157) A 32-year-old G2P0101 presents to labor and delivery at 34 weeks of gestation, complaining of regular uterine contractions about every 5 minutes for the past several hours. She has also noticed the passage of a clear fluid per vagina. A nurse places the patient on an external fetal monitor and calls you to evaluate her status. The external fetal monitor demonstrates a reactive fetal heart rate tracing, with regular uterine contractions occurring about every 3 to 4 minutes. On sterile speculum examination, the cervix is visually closed. A sample of pooled amniotic fluid seen in the vaginal vault is fern and nitrazine-positive. The patient has a temperature of 38.8C, pulse 102 beats per minute, blood pressure 100/60 mm Hg, and her fundus is tender to deep palpation. Her admission blood work comes back indicating a WBC of 19,000. The patient is very concerned because she had previously delivered a baby at 35 weeks who suffered from respiratory distress syndrome (RDS). You perform a bedside sonogram, which indicates oligohydramnios and a fetus whose size is appropriate for gestational age and with a cephalic presentation. Which of the following is the most appropriate next step in the management of this patient?
. Administer betamethasone
. Administer tocolytics
. Place a cervical cerclage
. Administer antibiotics
. Perform emergent cesarean section
158) A 30-year-old G1 with twin gestation at 28 weeks is being evaluated for vaginal bleeding and uterine contractions. A bedside ultrasound examination rules out the presence of a placenta previa. Fetal heart rate tracing is reactive on both twins, and the uterine contractions are every 2 to 3 minutes and last 60 seconds. A sterile speculum examination is negative for rupture membranes. A digital examination indicates that the cervix is 2 to 3 cm dilated and 50% effaced, and the presenting part is at −3 station. Tocolysis with magnesium sulfate is initiated and intravenous antibiotics are started for group B streptococcus prophylaxis. Betamethasone, a corticosteroid, is also administered. Which of the following statements regarding the use of betamethasone in the treatment of preterm labor is true?
. Betamethasone enhances the tocolytic effect of magnesium sulfate and decreases the risk of preterm delivery
. Betamethasone has been shown to decrease intraamniotic infections
. Betamethasone promotes fetal lung maturity and decreases the risk of respiratory distress syndrome
. The anti-inflammatory effect of betamethasone decreases the risk of GBS sepsis in the newborn
. Betamethasone is the only corticosteroid proven to cross the placenta
159) A 30-year-old G1 at 28 weeks gestation with a twin pregnancy is admitted to the hospital for preterm labor with regular painful contractions every 2 minutes. She is 3 cm dilated with membranes intact and a small amount of bloody show. Ultrasound reveals growth restriction of twin A and oligohydramnios, otherwise normal anatomy. Twin B has normal anatomy and has appropriate-for-gestational-age weight. Which of the following is a contraindication to the use of indomethacin as a tocolytic in this patient?
. Twin gestation
. Gestational age greater than 26 weeks
. Vaginal bleeding
. Oligohydramnios
. Fetal growth restriction
160) A 34-year-old G2P1 at 31 weeks gestation with a known placenta previa presents to the hospital with vaginal bleeding. On assessment, she has normal vital signs and the fetal heart rate tracing is 140 beats per minute with accelerations and no decelerations. No uterine contractions are demonstrated on external tocometer. Heavy vaginal bleeding is noted. Which of the following is the best next step in the management of this patient?
. Administer intramuscular terbutaline
. Administer methylergonovine
. Admit and stabilize the patient
. Perform cesarean delivery
. Induce labor
161) A 34-year-old G2P1 at 31 weeks gestation with a known placenta previa is admitted to the hospital for vaginal bleeding. The patient continues to bleed heavily and you observe persistent late decelerations on the fetal heart monitor with loss of variability in the baseline. Her blood pressure and pulse are normal. You explain to the patient that she needs to be delivered. The patient is delivered by cesarean section under general anesthesia. The baby and placenta are easily delivered, but the uterus is noted to be boggy and atonic despite intravenous infusion of Pitocin. Which of the following is contraindicated in this patient for the treatment of uterine atony?
. Methylergonovine (Methergine) administered intramuscularly
. Prostaglandin F2α (Hemabate) suppositories
. Misoprostol (Cytotec) suppositories
. Terbutaline administered intravenously-
. Prostaglandin E2 suppositories
162) A 20-year-old G1P0 at 30 weeks gestation with a known placenta previa is delivered by cesarean section under general anesthesia for vaginal bleeding and nonreassuring fetal heart rate tracing. The baby is easily delivered, but the placenta is adherent to the uterus and cannot be completely removed, and heavy uterine bleeding is noted. Which of the following is the best next step in the management of this patient?
. Administer methylergonovine (Methergine) intramuscularly
. Administer misoprostol (Cytotec) suppositories per rectum
. Administer prostaglandin F2α (Hemabate) intramuscularly
. Perform hysterectomy
. Close the uterine incision and perform curettage
163) A 38-year-old G1P1 comes to see you for her first prenatal visit at 10 weeks gestational age. She had a previous term vaginal delivery without any complications. You detect fetal heart tones at this visit, and her uterine size is consistent with dates. You also draw her prenatal labs at this visit and tell her to follow up in 4 weeks for a return OB visit. Two weeks later, the results of the patient’s prenatal labs come back. Her blood type is A–, with an anti D antibody titer of 1:4. Which of the following is the most appropriate next step in the management of this patient?
. Schedule an amniocentesis for amniotic fluid bilirubin at 16 weeks
. Repeat the titer in 4 weeks-
. Repeat the titer at 28 weeks
. Schedule Percutaneous Umbilical Blood Sampling (PUBS) to determine fetal hematocrit at 20 weeks
. Schedule PUBS as soon as possible to determine fetal blood type
164) A 27-year-old G1P0 woman at 27 weeks’ gestation presents to the emergency department after a motor vehicle accident. The patient denies any abdominal pain or cramping, contractions, or vaginal bleeding. Examination reveals a gravid, non-tender abdomen and a closed, non-effaced cervix with no evidence of vaginal bleeding. Fetal heart monitoring shows a fetal heart rate of 145/min, with variable accelerations and no decelerations. The patient is Rh negative with no history of blood transfusion, while the father is of unknown Rh status and unavailable. The results of the Kleihauer-Betke test, in which maternal blood is exposed to acid, shows a combination of pale and stained RBCs. Which of the following is the best next step in management?
Administer an appropriate dose of intramuscular Rh0(D) immune globulin
Amniocentesis to measure the amniotic fluid bilirubin level
Emergent cesarean section
Induction of vaginal labor with prostaglandins and oxytocin
Treatment with betamethasone
165) A 27-year-old G1 woman is 20 weeks pregnant. She is currently in her third year of a family practice residency and would like to travel to Africa and Asia as part of an outreach mission with her program. She has received all of her childhood immunizations. She presents to the obstetric clinic inquiring about the safety of immunizations during pregnancy. Which of the following vaccines is contraindicated in pregnancy?
Varicella
Hepatitis B
Influenza
Tetanus
Typhoid
166) A 28-year-old G0 woman presents to the clinic complaining of inability to conceive and amenorrhea. She has been taking a low-dose oral contraceptive pill for the past 6 years, which she discontinued 3 months ago when she and her husband decided they wanted to have children. They have been sexually active with each other two to three times per week over the past 3 months, but the patient has not become pregnant. The patient denies a history of sexually transmitted disease and states that until recently she has always had regular menstrual cycles. She has not had a period since discontinuation of the oral contraceptive. Which ofthe following is the most appropriate next step?
Administer a progesterone challenge
Check follicle-stimulating hormone and luteinizing hormone levels
Observation
Perform a hysterosalpingogram
Perform a pelvic ultrasound
167) A 31-year-old G3P2 woman at 37 weeks’ gestation presents to the labor and delivery floor after 2 hours of contractions of increasing frequency and intensity. An epidural anesthetic is requested on admission and placed. The patient continues to have contractions for the next 15 hours, during which time her membranes rupture spontaneously. Vaginal examination at that time reveals a cervix that is soft, 3 cm dilated, in an anterior position, and 80% effaced. The fetal head is at the -1 station. Fetal heart tracings reveal a baseline heart rate of 156/min, with variable accelerations and no significant decelerations. Which of the following is the best next step in management?
Apply intravaginal prostaglandin E2
Attempt forceps-facilitated delivery
Begin an infusion of oxytocin
Increase the rate of intravenous fluids to hydrate the patient
Proceed to cesarean section
168) A 30-year-old G3P2 woman at 25 weeks’ gestation has a history of gestational diabetes in her previous pregnancy. Her fasting blood glucose level at her initial 10-week screening visit was 110 mg/dL and urinalysis was negative for glucose in the urine. The patient has not been taking her own blood sugars at home, but she has been adhering to a low-carbohydrate diet. Over the past several weeks, she has noticed increased fatigue and polyuria. Which of the following is the next most appropriate step?
Administer a 3-hour glucose tolerance test
Administer a 50-g 1-hour glucose tolerance test
Begin insulin therapy
Check a urinalysis and start insulin if urinalysis reveals glucose in the urine
Prescribe metformin to be taken daily
169) A 34-year-old G1P0 woman at 29 weeks’ gestation presents to the emergency department complaining of 2 hours of vaginal bleeding. The bleeding recently stopped, but she was diagnosed earlier with placenta previa by ultrasound. She denies any abdominal pain, cramping, or contractions associated with the bleeding. Her temperature is 36.8C (98.2F), blood pressure is 118/72 mm Hg, pulse is 75/min, and respiratory rate is 13/min. She reports she is Rh positive, her hemoglobin is 11.1 g/dL, and coagulation tests, fibrinogen, and D-dimer levels are all normal. On examination her gravid abdomen is non-tender. Fetal heart monitoring is reassuring, with a heart rate of 155/min, variable accelerations, and no decelerations. Two large-bore peripheral intravenous lines are inserted and two units of blood are typed and crossed. What is the most appropriate next step in management?
Admit to the antenatal unit for bed rest and betamethasone
Admit to the antenatal unit for bed rest and blood transfusion
Admit to the antenatal unit for bed rest and treatment with RhO(D) immune globulin
Emergent cesarean section
Outpatient expectant management
170) A 32-year-old G3P2 woman at 35 weeks’ gestation has a past medical history significant for hypertension. She was well-controlled on hydrochlorothiazide and lisinopril as an outpatient, but these drugs were discontinued when she found out that she was pregnant. Her blood pressure has been relatively well controlled in the 120–130 mm Hg systolic range without medication, and urinalysis has consistently been negative for proteinuria at each of her prenatal visits. She presents now to the obstetric clinic with a blood pressure of 142/84 mmHg. A 24hour urine specimen yields 0.35 g of proteinuria. Which of the following is the most appropriate next step?
Administer oral furosemide
Prepare for emergent delivery
Restart the patient’s prepregnancy antihypertensive regimen
Restricted activity and close monitoring as an outpatient following initial inpatient evaluation
Start hydralazine
171) A 32-year-old G2P1 woman at 35 weeks’ gestation presents to her obstetrician for a routine prenatal check-up. The mother has been previously diagnosed with mild preeclampsia, which the obstetrician has chosen to manage expectantly. During the visit, a biophysical profile is performed and the amniotic fluid index is found to be <5 cm, indicating the development of oligohydramnios. The biophysical profile is otherwise normal, with a total score of 8/10 and reassuring fetal heart tracings. How should oligohydramnios be managed in this patient?
Administration of betamethasone, then cesarean section in 24 hours
Amnioinfusion with normal saline solution
Biweekly fetal biophysical profiles
Emergent cesarean section
No change in management is necessary
172) A 24-year-old G1P0 woman at 31 weeks’ gestation presents to the emergency department with a 4-hour history of abdominal cramping and contractions. The contractions have been regularly spaced at 10 minutes, but seem to be increasing in intensity. She has had a small amount of vaginal discharge, but is unable to definitively say whether her water has broken. She has not had any vaginal bleeding. Her temperature is 36.8C (98.3F), blood pressure is 137/84 mm Hg, pulse is 87/min, and respiratory rate is 12/min. Physical examination reveals a non-tender abdomen with palpable contractions every 8 minutes. Which of the following is the best next step in management?
Cervical culture for Group B streptococci
Digital cervical examination and assessment of dilation and effacement
Quantification of strength and timing of contractions with an external tocometer
Speculum examination to rule out rupture of membranes and visually assess cervical dilation and effacement
Ultrasound examination of the fetus
173) A woman brings her 15-year-old daughter to her pediatrician for concerns about hair growth. The child has always had a lot of body hair and has been shaving her legs since she was 12 years old. The mother reports that her daughter has recently been noticing more hair, especially along the upper lip and on the chest and abdomen. The child is clearly distressed about her appearance. Further questioning reveals that although the girl had her first menses at 11 years old, her menstrual cycles are irregular, and she sometimes skips cycles for months at a time. Physical examination reveals a young, heavy-set, olive-skinned teenager with moderate acne and dark hair growth along her upper lip, across her chest, and over her lower abdomen. She exercises regularly. Which of the following is the most appropriate treatment for this child’s hirsutism?
Danazol
Insulin
Levothyroxine
Oral contraceptives
Pergolide
174) A 21-year-old woman at 36 weeks gestation is admitted for delivery. She has severe preeclampsia. Her blood pressure is 190/110 mmHg, pulse is 80/min and respirations are 16/min. Physical examination shows 3+ pitting edema of the legs and brisk deep tendon reflexes. Fundoscopic examination shows no abnormalities. Laboratory studies show elevated BUN, serum creatinine and serum transaminases. Urinalysis shows 4+ proteinuria. Intravenous hydralazine and magnesium sulfate was initiated on admission. After stabilization, intravenous oxytocin and artificial rupture of membranes (AROM) was administered for induction of labor. Two hours later, her blood pressure is 150/90 mmHg, pulse is 78/min and respirations are 9/min. Repeat examination shows hyporeflexia and a completely effaced cervix that is 5 cm dilated. Which of the following is the most appropriate next step in management?
. Stop hydralazine and do an emergency caesarian section
. Stop magnesium sulfate and give calcium gluconate
. Stop hydralazine and monitor serum cyanide level
. Stop intravenous oxytocin and intubate the patient
. Continue current treatment and proceed with delivery
175) An 18-year-old woman comes to the physician for her annual physical examination. Her past medical history is unremarkable and she takes no medications. Her last menstrual period was 2 weeks ago, and she has regular menses lasting 4-5 days every 28 days. The patient became sexually active at age 16 and has had 3 partners since then. She is currently in a monogamous relationship with her boyfriend of a year and uses condoms regularly. The patient has no vaginal discharge, urinary complaints, or weight changes. Vital signs and general physical examination are within normal limits. She inquires about cervical cancer screening and human papillomavirus vaccine, which she has not received. What is the most appropriate next step in management of this patient?
. Give human papillomavirus (HPV) vaccine now
. Perform Pap smear now
. Perform Pap smear with HPV testing
. Reassurance and follow-up next year
. Test for HPV and, if negative, give vaccine
176) A 30-year-old woman, gravida 2, para 1, at 37 weeks gestation is brought to the emergency department because of acute onset intense uterine contractions and vaginal bleeding. She has been followed closely for pre-eclampsia since her 32nd week of gestation. Her temperature is 37.0°C (98.7°F), blood pressure is 140/86mmHg, pulse is 92/min and respirations are 18/min. Physical examination shows uterine tenderness and hyperactivity and moderate vaginal bleeding. Pelvic examination shows an effaced and 3cm dilated cervix. Ultrasonography shows a fundic placenta and a fetus in the cephalic position. Fetal heart tracing shows 140/min with good long-term and beat-to beat variability. After initial resuscitation the bleeding is stopped. Which of the following is the most appropriate next step in management?
. Vaginal delivery with augmentation of labor, if necessary
. Emergency cesarean section
. Perform tocolysis and schedule cesarean section within 48 hours
. Forceps delivery
. Conservative management at home
177) A 42-year-old postmenopausal woman presents to the clinic complaining of vague abdominal pain, early satiety, and a 9-kg (20-lb) unintended weight loss. She has a history of normal Pap smears. On physical examination her abdomen is firm, with evidence of ascites and a firm, irregular, and fixed left adnexal mass palpated on vaginal examination. CT scan of the abdomen and pelvis confirms the presence of an ovarian mass that has features that are highly suspicious for cancer. What is the best means to correctly diagnose and stage this mass?
Measurement of α-fetoprotein, β-human chorionic gonadotropin, and lactate dehydrogenase levels
Measurement of cancer antigen 125 level
MRI of the abdomen and pelvis
Percutaneous needle biopsy of the tumor for histopathologic staining
Surgical exploration with tumor debulking and nodal sampling
178) A 55-year-old woman is brought to the emergency department by fi re and rescue personnel because of intractable back and thigh pain for the past 3 hours. Upon presentation she says that the pain is 9 of 10 in severity and localized to her lower back. She lives with her sister, and she has no primary care physician. She denies any complaints aside from fatigue, which she attributes to her multiple jobs and caring for her sister’s children. She has a pulse of 110/min, blood pressure of 140/88 mm Hg, respiratory rate of 20/min, and temperature of 37.8C (100.1F). On physical examination she is exquisitely tender over the L2–3 area of the spine. She also has point tenderness over the anterior right thigh. Sensation is intact over the lower extremities bilaterally and she has 5/5 strength in the lower extremities bilaterally. Breast examination reveals a retracted nipple and dimpling of the right breast. What will likely represent the mainstay of treatment for this patient’s symptoms?
Bone marrow transplant
Chemotherapy
Hormone replacement therapy
Radiation therapy
Surgery
179) A 57-year-old G3P3 woman presents to her gynecologist with complaints of vaginal pruritus and increased vaginal discharge. The patient has no history of gynecologic surgery or sexually transmitted diseases; she is not currently sexually active. A bimanual examination and Pap smear are performed. The Pap smear is positive for malignant squamous cells. Follow up colposcopy shows no cervical lesions, but a small lesion is noted on the lower vagina. Biopsy of this lesion confirms the diagnosis of vaginal squamous cell cancer, while cross-sectional imaging excludes invasion of surrounding tissues. What is the most appropriate course of treatment?
Chemotherapy
Radiation therapy
Surgical excision
Surgical excision and chemotherapy
Surgical excision and radiation therapy
180) A 33-year-old G1P1 woman presents to her gynecologist for a Pap smear. It has been several years since she last saw a physician. She is not currently sexually active, but takes oral contraceptives. Her vaginal examination is normal, but her Pap smear shows moderate-grade cervical intraepithelial neoplasia. The patient undergoes colposcopy and biopsies, which confirm the diagnosis. What is the most appropriate management of this patient?
Continued annual Pap smears
Loop electrosurgical excision procedure
Radiation therapy
Serial colposcopies every 3–4 months
Total abdominal hysterectomy
181) A 48-year-old woman presents to her gynecologist because of vaginal bleeding. She states that after a year of hot flashes and irregular cycles, she finally stopped menstruating 4 months ago. Two days ago she began having some vaginal bleeding that was very similar to her prior menses. She is concerned because she heard that the first sign of endometrial cancer in postmenopausal women is vaginal bleeding. She is an otherwise healthy woman with no medical problems. She exercises three times a week and takes multivitamins. She had three children when she was 29–35 years old. She used oral contraceptive pills for contraception from the time she was 18 until she got married at the age of 28. Which of the following is the most appropriate next step in managing this woman’s vaginal bleeding?
Abdominal ultrasound
Endometrial biopsy
Follow-up examination in 6 months
Measure serum level of follicle-stimulating hormone
Prescription of testosterone cream
182) A 35-year-old G4P4 obese woman is referred to her gynecology clinic by her primary care physician for heavy menstruation and irregular cycles. She has noticed these symptoms for several months. She reports being a “late bloomer,” with onset of menses at age 13 years. She is sexually active and monogamous with her partner of 2 years. She is taking oral contraceptive pills and has a 5-year smoking history. An endometrial biopsy is read as “endometrial hyperplasia, cannot rule out intraepithelial carcinoma.” β-Human chorionic gonadotropin testing is negative. Which of the following most likely contributed to this abnormality?
Body habitus
Late menarche
Multiparity
Sexual activity
Smoking history
183) An 18-year-old woman presents to the clinic because of 6 hours of severe abdominal pain, nausea, and vomiting. She describes 6 days of mild lower abdominal pain, low-grade fever, and abnormal vaginal discharge. She is sexually active with two male partners, and her last menstrual period was 10 days ago. Her temperature is 39.5C (103.2F), blood pressure is 100/60 mm Hg, heart rate is 110/min, and respiratory rate is 18/min. Physical examination reveals involuntary abdominal guarding. The patient will not allow a pelvic examination. Which of the following is the most appropriate management?
Discharge home with oral antibiotics
Discharge home without antibiotics
Hospitalization for intravenous antibiotics and hydration
Hospitalization for intravenous hydration without antibiotics
Hospitalization with oral antibiotics and intravenous hydration
184) A 65-year-old G2P2 postmenopausal woman presents to a gynecologist for the first time in many years complaining of vaginal bleeding, pelvic pain, and increased urinary frequency. She reports she is sexually active with her husband. After an appropriate work-up, a diagnosis of locally invasive squamous cell carcinoma of the cervix is made. The tumor has extended approximately 9 mm into the cervical stroma, grading the cancer as stage IB. The patient is informed of the diagnosis and wishes to undergo definitive therapy. What is the definitive therapy for this patient’s disease?
Chemotherapy
Cold knife cone excision
Loop electrosurgical excision procedure
Radical hysterectomy
Uterine artery embolization
185) A 29-year-old African-American woman comes to the physician after discovering a mass on breast self-examination. Her last menstrual period was 2 weeks ago. She reports occasional bilateral gray nipple discharge that has not changed since menarche. She has no significant past medical history and does not take any medications. Examination reveals a 1.5-cm fluctuant mass in the upper and outer quadrant of the left breast. Which of the following is the best next step in management?
Cytological examination of the nipple discharge
Fine-needle aspiration
Incisional biopsy
Mammography
Reassurance and continued breast self-examination
186) A 26-year-old G0 woman is seen in her gynecologist’s office for a routine examination. She reports that she has been sexually active with four partners and has been treated for gonorrhea once in the past year. She has otherwise been healthy. Physical examination is unremarkable. Results of a Pap smear suggest a low-grade squamous intraepithelial lesion. What is the most appropriate next step in management?
Instruct patient to return immediately for repeat Pap smear
Reassure patient of results and instruct her to return to the office in 6 months
Refer immediately for colposcopy
Test for human papillomavirus types 6 and 11
Test for human papillomavirus types 16 and 18
187) A 52-year-old postmenopausal woman who was diagnosed with advanced ovarian cancer presents to the clinic to discuss her treatment options. She has had a CT of the abdominalpelvic region that showed extensive disease extending from her left ovary and involving her uterus along with large pelvic nodes. What is the best treatment for this patient?
Chemotherapy and radiation therapy to the pelvis followed by surgery
Paclitaxel and cisplatin therapy followed by CT surveillance
Radiation therapy to the abdomen and pelvis
Surgical debulking with a postsurgical course of pacitaxel and cisplatin
Tumor debulking alone
188) A 22-year-old primiparous woman is in premature labor at 30 weeks’ gestation. Despite administration of tocolytic agents, it seems she will deliver soon. Pulmonary maturity might be enhanced by the administration of which of the following drugs?
Magnesium sulfate
Betamethasone
Hydroxyprogesterone
Chloroprocaine
Digitalis
189) A 22-year-old woman with cystic fibrosis is engaged to be married and asks you about childbearing. How should you advise her?
An amniocentesis should be done to detect fetal cystic fibrosis.
Pregnancy is contraindicated because maternal mortality is significantly increased.
Her children have a 25% chance of having cystic fibrosis.
Pregnancy and delivery are usually successful with special care and precautions.
She should use nasal oxygen throughout pregnancy to minimize fetal hypoxemia
190) A 34-year-old woman, gravida 3, para 2, at 16 weeks' gestation comes to the physician concerned that she may have been exposed to an infectious disease. Yesterday, she and her 5-year-old son spent a day at the beach with one of his classmates. This morning, the classmate was sent home from school with a fever and rash that the teacher thought, were suspicious for chickenpox. The patient is unsure whether she had chickenpox as a child. Her temperature is 37 C (98.6 F), blood pressure is 100/70 mm Hg, pulse is 88/min, and respirations are 16/min. Her examination is unremarkable. An inquiry made by the physician confirms that the classmate has chickenpox. Which of the following is the most appropriate next step in management?
Check an IgG varicella serology
Wait to see whether a rash develops
Administer IV acyclovir
Administer oral acyclovir
Administer varicella vaccine
191) A 26-year-old primigravid woman at 10-weeks' gestation comes to the physician for a routine prenatal appointment Her dating is based on a 6-week ultrasound. She has sickle-cell anemia. She has no past surgical history, takes prenatal vitamins, and has no known drug allergies. She tells the physician that she recently learned that the father of the baby has sickle-cell trait. On examination, her uterus is appropriate for a 10-week gestation, and fetal heart tones are heard. Her hematocrit is 37%. What is the most appropriate next step in the management of this patient?
Genetic counseling
Obstetric ultrasound
Hydroxyurea
IV hydration
Blood transfusion
192) A 22-year-old woman comes to the physician seeking advice. Last night, while she was having sexual intercourse, the condom broke. She is very concerned that she may become pregnant and wants to know whether she can do anything at this point. She has no medical problems and has never had surgery. She takes ibuprofen for dysmenorrhea. She is allergic to sulfa drugs. On physical examination, she is anxious and intermittently sobbing. Her temperature is 37 C (98.6 F), blood pressure is 140/90 mm Hg, pulse is 98/min, and respirations are 24/min. The remainder of her physical examination is unremarkable. A urine pregnancy test is negative. Which of the following is the most appropriate pharmacotherapy?
Clomiphene
Gentamicin
Labetalol
Norgestrel/ethinyl estradiol
Trimethoprim-sulfamethoxazole
193) A 39-year-old woman, gravida 3, para 2 at 34 weeks' gestation, with a known history of chronic hypertension, is found to have a blood pressure of 180/115 mm Hg at a routine prenatal visit. Her prenatal course had been otherwise unremarkable. She is transferred to the labor and delivery ward for further management. IV antihypertensive medications should be given to this patient with a goal of which of the following blood pressures?
90/60 mm Hg
100/75 mm Hg
120/80 mm Hg
150/95 mm Hg
180/110 mm Hg
194) A 33-year-old woman comes to the physician because she has not had a menstrual period for 6 months. Prior to this she had a normal period every 29 days that lasted for 4 days. She has noted some weight gain in the past few months. She has a history of hepatitis A infection 6 years ago and had an appendectomy at age 12. She takes no medications and has no allergies to medications. Her father died of acute pancreatitis 3 years ago. Her mother is alive and well with no medical problems. Which of the following is the most appropriate next step in diagnosis?
Amylase
FSH
P-hCG
Liver function tests
TSH
195) A 35-year-old G1 PO woman at 35 weeks gestation by last menstrual period and confirmed by a first trimester ultrasound comes to the hospital because of leakage of fluid one hour ago. She received her prenatal care at an outside hospital and the records are not available. She reports no other complications with this pregnancy thus far. She reports no medical problems, takes no daily medications other than a prenatal vitamin, and has no allergies to medications. She is examined and preterm premature rupture of membranes is confirmed by a positive nitrazine test, positive pooling test, and a positive ferning test. She is 2 cm dilated, 50% effaced, and at -2 station. She is admitted to the hospital. Transabdominal ultrasound confirms that the fetus is in a vertex presentation, and the amniotic fluid index is decreased at 3 cm. Fetal heart rate and contraction monitoring is started, and occasional uterine contractions are noted on the monitor. Which of the following is the most appropriate next step in management?
. Urgent cesarean section
. Tocolysis
. Amnio dye test to confirm rupture of membranes
. Betamethasone IM
. Penicillin prophylaxis
196) A 26-year-old woman, gravida 2, para 2, complains of loss of small amounts of urine immediately after a spontaneous vaginal delivery. She received epidural anesthesia during labor and delivery because of severe pain. She has no fever, dysuria, urgency, or hematuria. She has no other medical problems, takes no medication except prenatal vitamins, and has no known drug allergies. Her vital signs are normal. Examination shows a soft, non-tender abdomen. Pelvic examination is normal. The patient voids 30-40ml of urine each time; her postvoid residual volume is 400 ml. The patient's labs reveal: Urine: Specific gravity: 1.020, Blood: trace, glucose: negative, Leukocytes esterase: negative, Nitrite: negative, WBC: 1-2/hpf, RBC: 3-4hpf. Which of the following is the most appropriate treatment for her incontinence?
. Place permanent Foley catheter
. Do intermittent catheterization
. Start oxybutynin
. Urethropexy
. Perform urodynamic testing
197) A 30-year-old G2 P1 woman at 38 weeks gestation comes to the hospital because of regular and painful uterine contractions that started two hours ago. Pelvic examination reveals bulging membranes, and her cervix is 50% effaced and dilated to 3 cm. Her pregnancy was complicated by first trimester hemorrhage of unknown cause. Her past medical history is unremarkable. Upon observing the fetal heart rate monitor and an external tocometer for 20 minutes, you note 6 contractions. You also note 4 separate 15 - 20 beat/min decreases in the fetal heart rate with every contraction. The depth and duration of decelerations vary with successive uterine contractions. Which of the following is the most appropriate next step in the management of this patient?
. Oxygen administration and change in maternal position
. Artificial rupture of membranes
. Amnioinfusion
. Fetal scalp pH testing
. Emergent cesarean section
198) A 24-year-old woman presents to your office with a self-palpated breast lump. She discovered the mass 2 days ago while taking a shower and noted that it is mildly tender. Her menstrual periods are regular, occurring every 26 days. Her last menstrual period (LMP) was 3 weeks ago. Her past medical history is insignificant. She has no family history of breast cancer. Physical examination reveals a lump in the superior outer quadrant of the right breast without palpable lymphadenopathy. Which of the following is the most reasonable next step in the management of this patient?
. Ask her to return shortly after the menstrual period
. Order mammography
. Proceed with fine needle aspiration biopsy
. Suggest excisional biopsy
. Reassure that the mass is benign and no follow-up is necessary
199) A 32-year-old woman who is one week postpartum presents with dull pain in her left leg for the past three days. She denies any history of trauma, fever or chills. Her pregnancy and delivery were uncomplicated, and her past medical history is unremarkable. She does not use tobacco, alcohol or illicit drugs. Her temperature is 37.2C (98.9 F) and blood pressure is 120/76 mm Hg. Physical examination reveals a swollen, tender, and mildly erythematous left leg. Doppler ultrasonogram reveals a thrombus in the superficial part of the femoral vein of the left leg. Which of the following is the most appropriate next step in management?
. Reassurance and ibuprofen
. Anticoagulation with heparin
. Inferior vena cava filter
. Thrombolytic therapy
. Antistaphylococcal antibiotics
200) A 24-year-old woman, gravida 2, para 2, comes to the physician for a yearly physical and birth control counseling. She is currently using the rhythm method of birth control, but has heard that this method has a high failure rate and would like to try a different method. Several of her friends use the intrauterine device (IUD), and she is wondering whether she could also use this method. Past medical history is significant for eczema. Past surgical history is significant for a right ovarian cystectomy 2 years ago. Past gynecologic history is significant for multiple episodes of Chlamydia cervicitis and two episodes of pelvic inflammatory disease (PID), the most recent episode occurring 1 year ago. She takes acetaminophen for occasional tension headaches. She is allergic to penicillin. She smokes onehalf pack of cigarettes per day. Physical examination is unremarkable. Which of the following would be the best recommendation for this patient regarding her birth control method?
"The IUD is absolutely contraindicated."
"The IUD is recommended."
"The IUD is recommended if cervical cultures are negative."
"The oral contraceptive pill is absolutely contraindicated."
"The rhythm method is recommended."
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