Giving the Pharm to BioPsych

Definition: the steps by which drugs are absorbed, distributed, metbolized and excreted

Black Gangster Disciples

Psychopharmacology

Pharmacokinetics

Injection

What is the fastest route to administer drugs?

Inject into abdominal wall

Inject into a vein

Place underneath the tongue

Inject into a muscle

Which is not administered with a needle?

Intraperitoneal

Intravenous

Sublingual

Intracerebral

Which is an injection into the space beneath the skin?

Intracerebral

Intracerebroventricular

Subcutaneous

Intraperitoneal

What are the 4 components (in order) of pharmacokinetics?

Insertion/distribution/indigestion/excretion

Absorption, digestion, metabolism, excretion

Absorption, distribution, metabolism, excretion

John, Paul, George, Ringo

The dope-response curve is....

Determination of the point where adverse side effects decrease

Lipid solubility

Best way to measure effectiveness of a drug

Point where drug tolerance begins

Term to describe the rate a drug reaches sites of action within the brain

Therapeutic index

Dope-response

Metabolism

Lipid-solubility

Therapeutic index

Dose that produces a toxic effect in 50% of subjects

Dose that produces a desired effect in 50% of subjects

Determination of when withdrawal begins

A measure of a drug's safety

Term for when dysphoria

Withdrawal

Sentization

Tolerance

Addiction

Definition of affinity

Readiness in which 2 molecules join together

When 2 or more molecules separate

A cable TV company

Increased tolerance

What are 2 reasons drugs vary in their effectiveness?

Compound structure / manufacturers

Expiration date of drug / form of administration

Different sites of action / affinity for binding varies

Delayed absorption into digestion system / interaction with different drugs

Role of an antagonist

Block postsynaptic effects

Facilitate postsynaptic effects

Support the nervous system

Increase effectiveness

What prevents the neurotransmitter from activating the receptor?

Indirect antagonists

Direct antagonists

Divergents

Reuptake synapses

Often referred as the main excitatory neurotransmitters

Glutamates

GABA

Spaghetti-Os

HVAC

Neurotransmitter for mood regulation

Opioids

Serotonin

Histamine

GABA

Glutamate is removed from the synapse by excitatory amino acid transporters

True

False

Binding sites for GABA

Bicuculline, muscimol, diazepam, alprazolam

Bicolax, muscimol, diazepam, serotonin

Duramorph, talwin, diazepam, adzenys

Bicuculline, muscus, desoxyn, alprazolam

Acetylcholinergic neurons are located in the brain stem

True

False

I got nothing

Amphetamine and methamphetamine

Receive dopamine and norepinephrine

Releases norepinephrine

Releases dopamine and norepinephrine

Receives dopamine

Which are monoamine neurotransmitters?

Dopamine, norepinephrine and epinephrine

Domamine, curare, enzymes

Atropine, nicotine, botulinum

Jean Terrell, Scherrie Payne, Lynda Laurence

Opiates and naloxone are considered

Peptides

Lipids

Schedule IV drugs

Rapha is defined as

Divide or separate

Seam or crease

Jackie Gleason on the Honeymooners

A2's has pets named (check all that apply)

Boo and Scout

Atticus

Ringo

EXTRA CREDIT: Who are Jean Terrell, Scherrie Payne, Lynda Laurence

The Motels

The Supremes

Charlie's Angels

Members of the 5th Dimension

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