Part 4 Immunology(150-199) prof. Keit vanseth
Immunology Mastery Quiz
Test your knowledge of immunology with our comprehensive quiz designed for students and professionals alike. With a focus on key concepts such as phagocytosis, T cells, and antibodies, this quiz will challenge your understanding of the immune system.
Whether you're preparing for exams or just looking to refresh your knowledge, this quiz offers:
- 50 detailed questions
- A variety of topics within immunology
- Instant feedback on your answers
150. The following answers are true for phagocytosis, EXCEPT:
σ½ Supported by complement
σ½ Opsonisation
σ½ Ingest pathogen
σ¾ NK cell
151. The following activity is indicated T cell cytotoxic:
σ½ MHC-II restricted
σ¾ MHC-I restricted
σ½ B cell activation
σ½ Epitope presented to CD4
152. Which cell is T helper:
σ½ CD8
σ½ CD14
σ¾ CD4
σ½ CD15
153. Which cell is Monocyte:
σ½ CD8
σ¾ CD14
σ½ CD4
σ½ CD15
154. Which cell is Granulocyte:
σ¾ Basophil
σ½ Monocyte
σ½ Lymphocyte
σ½ Macrophage
155. The following statements are true for Antibodies, EXCEPT :
σ½ Fc receptor for complement
σ½ Extra domain for IgM
σ½ Made of heavy and light chains
σ¾ Receptors for antigens are monovalent
156. The following statements are true for the antigenic determinant :
σ½ Is the combining site of an antibody
σ½ Is paratope
σ¾ Small part of the antigen
σ½ Is paratope and Small part of the antigen
157. The basic monomeric Immunoglobulin unit is:
σ½ Four polypeptide chains
σ¾ One of five major classes
σ½ Four polypeptide chains and One of five major classes
σ½ Synthesized by a T-cell
158. Which of the following are mechanisms for neutrophil phagocytosis:
σ½ Azerophilic granules
σ½ defensins
σ½ Hydrolytic enzymes
σ¾ Azerophilic granules and defensins
159. Identity the phagocytic cells from the following combinations:
σ¾ Macrophage and neutrophil
σ½ Lymphocyte and eosinophil
σ½ Macrophage and eosinophil
σ½ Eosinophil and neutrophil
160. Class II MHC proteins are :
σ½ Recognized by CD4
σ½ Recognized by CD8
σ½ Used to participate in helper function
σ¾ Recognized by CD4 and Used to participate in helper function
161. The function of major histocompatibility complex is:
σ½ Degrade T4 and T8 polypeptides
σ½ Bind antibody for cytokine secretion
σ½ Bind complement for cell lysis
σ¾ Bind epitope for presentation to T-cells
162. The following statements are true for Class II MHC molecules, EXCEPT :
σ½ Able to carry an antigen fragment
σ½ Recognized by the CD4
σ¾ Presented antigen to Tc cells
σ½ Used to participate in Th function
163. All of the following are a part of innate immune respond, EXCEPT :
σ½ Pathways of complement activation
σ½ Natural Killer cells
σ¾ T cells secrete antibody
σ½ Macrophage secrete cytokines
164. All of the following are function of IgG, EXCEPT :
σ¾ Primary response to antigen
σ½ Opsonize bacteries
σ½ Activate complement
σ½ Cross placenta
165. The class of an immunoglobulin is determined by:
σ½ Class I and II MHC
σ½ The light chain
σ½ The antigen
σ¾ The heavy chain
166. Light chains are :
σ½ Specific for each class of antibody
σ¾ Complement fixation
σ½ Reactive with antigen
σ½ Have only a constant region
167. Each of the following statement is a characteristic of antibodies, EXCEPT:
σ½ They have four glycoprotein chains
σ½ They contain variable region
σ¾ They are phagocytes
σ½ They have specific receptor for antigen
168. Cytokines are produced by cells of the immune system in response to various antigen, EXCEPT:
σ½ Activate cell function
σ½ Facilitate cell lysis
σ¾ Opsonization antigen
σ½ Cause histamine release
169. The following answer is NOT true for interleukins?:
σ½ Produced by T cells
σ½ Regulation between cells
σ½ They are not in stock
σ¾ Produced by antigen
170. Which of the following are true statements:
σ¾ IgM and IgG can fix complement
σ½ IgA can fix complement
σ½ IgE lyses allergen
σ½ IgD provides immunization
171. An antigenic determinant is:
σ¾ A fragment of Antigen
σ½ Recognized by a epitope
σ½ Molecule of antigen
σ½ Recognized by macrophage
172. The following statement is the basic monomeric immunoglobulin unit, EXCEPT:
σ½ Composed of glycoproptein chains
σ½ Same protein type for all antibody classes
σ½ Able to associate with J- chain to form multimers
σ¾ The receptor is TCR
173. Class II MHC proteins are:
σ½ Recognized by the CD8 protein
σ½ Used to kill cytotoxic T-cells
σ¾ Participate in T helper function
σ½ Not able to carry an epitope
174. The following statement are for Class I MHC proteins, EXCEPT:
σ½ Able to carry an antigen fragment
σ½ Recognized by the CD8 protein
σ½ Killed target cells by Tc cells
σ¾ Participate in T helper function
175. Which properties do the T-cell receptor and the antibody share in common:
σ¾ Both recognize antigen fragments
σ½ Both are able to fix complement
σ½ Both have constant regions
σ½ Both are polypeptide chains
176. The specific type of functional activity of a T-cell following antigen recognition is determined by:
σ½ Antigen receptor
σ½ MHC class II presenting the antigen fragment
σ½ carbohydrate side chains
σ¾ CD4 or CD8 can bind antigens
177. The following statement are MOST closely related to each, EXCEPT:
σ½ Antigen
σ½ Allergen
σ½ Epitope
σ¾ Antibody
178. The Immunoglobulins are secreted by:
σ¾ Plasma cells
σ½ T-cells
σ½ B-cells
σ½ Macrophages
179. Antigen-antibody reactions can result in the following:
σ½ Killed antigen
σ½ Complement fixation
σ½ Virus neutralization
σ¾ All answers
180. Variable regions of immunoglobulin are:
σ½ Able to fix complement
σ½ N-terminal of heavy chains
σ½ C-terminal of heavy chains
σ¾ Specific recognition of antigen
181. The J-chain of immunoglobulin is :
σ½ Made only by epithelial cells
σ¾ Present in IgM
σ½ Present in IgG
σ½ Made by T cells
182. The T-cell receptor is:
σ¾ Recognized antigen fragments
σ½ Secreted by the T-cell
σ½ Recognized antibody
σ½ Bivalent
183. The following statement are for Target cell lysis and destruction, EXCEPT:
σ½ Cytotoxic T-cells recognizing specific epitopes on the target cell surface
σ½ Perforin released from antigen-specific cytotoxic T-cells
σ½ Complement binding to IgG and IgM which have bound to epitopes on the target cell
σ¾ Complement binding to IgE which have bound to epitopes on the cell surface
184. The following statement is true for helper T-cells :
σ½ Helper cells recognize antigen with MHC class I
σ½ Helper cells recognize antigen with MHC class I and II
σ½ Cytotoxic cells recognize antigen with MHC class
σ¾ Helper cells recognize antigen with MHC class II
185. The following statement are true for Cytokines, EXCEPT:
σ½ Control and regulate the immune response
σ½ Lymphokines are cytokines
σ½ Secreted by specialized cells
σ¾ Are complement
186. The function of cytokines are :
σ½ Bind to MHC class I
σ½ Specifically recognize antigens
σ½ Production of complement
σ¾ Regulation the immune cells
187. All of the following are true, EXCEPT :
σ½ An epitope is a fragment of a macromolecule
σ½ The variable regions contain the antigen recognition site
σ¾ An antigenic determinant is a paratope
The class of an immunoglobulin is determined by its heavy chain
188. The Natural Killer T Cells work in the immune system :
σ½ Adaptive immunity
σ¾ Link between Adaptive and Innate immune
σ½ Innate immunity
σ½ Adaptive immunity and Innate immunity
189. The following bonds is responsible for linking of antibody to its chains:
σ½ Van der Waals forces
σ½ Hydrophobic forces
σ½ Hydrogen bonds
σ¾ Disulfide bonds
190. The following organs do not affect by hepatitis virus, EXCEPT:
σ½ Heart
σ¾ Liver
σ½ Brain
σ½ Kidneys
191. Which of the following hepatitis viruses is RNA virus?:
σ¾ Hepatitis A virus
σ½ Hepatitis E virus
σ½ Hepatitis B virus
σ½ Hepatitis G virus
192. The following hepatitis can be prevented by vaccination :
σ½ Hepatitis B and C
σ½ Hepatitis C and E
σ½ Hepatitis D and C
σ¾ Hepatitis A and B
193. Which of the following immune cells are effective to destroying intracellular pathogens:
σ½ T helper cells
σ½ B cells
σ½ Antibodies
σ¾ T cytolytic cells
194. The following activities are belong to the B-cells :
σ½ Act as antigen-processing cells
σ½ Antibodies response to antigens
σ½ Differentiate into plasma cells
σ¾ Receptor antigen monovalent
195. Which of the following DOES NOT play a role in antigen presentation:
σ½ MHC class I molecules
σ½ MHC class II molecules
σ¾ MHC class III molecules
σ½ Complement
196. The variable regions in the light chains participate in:
σ½ Fc receptor binding.
σ¾ Epitope binding.
σ½ Affinity of the complement receptors.
σ½ Interaction of the Fab with cytokines.
197. Which type of antibody is MOST effective in activating complement?:
σ½ IgG1
σ½ IgG2
σ½ IgG3
σ¾ IgM
198. Which of the following antibody fragments consists of a dimer of the heavy-chain constant region but lacks the CH1 domains?:
σ½ F(ab)’2
σ½ F(ab)'
σ½ Fab
σ¾ Fc
199. Which part of antibody lack of constant domain:
σ¾ VL
σ½ CL
σ½ CL and CH
σ½ CH
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