Researchers were examining the mechanism of action of a new bacterial toxin that has been found to interfere with the epinephrine-GPCR pathway. They collected the following data from muscle cells without the toxin (- toxin) and with the toxin (+ toxin). Use these data to answer the next two questions.

Based on the data in the figures, which of the following is TRUE?
Phosphorylase kinase activity is reduced in the presence of the toxin
The G protein can never become activated in the presence of the toxin
Glycogenolysis can proceed as normal in the presence of the toxin
CAMP concentrations are lower in the presence of the toxin
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