Endocrine 2
Endocrine Insights: Diabetes Management Quiz
Test your knowledge on diabetes management with our comprehensive quiz focused on oral antidiabetic agents and diabetic ketoacidosis. This quiz is designed for healthcare professionals, students, and anyone interested in understanding the complexities of endocrine disorders.
Key Features:
- In-depth questions on diabetes medications
- Insights into diabetic ketoacidosis
- Match enzymatic fun
ctions with their reactions
Which of the following oral antidiabetic agents are often associated with weight gain in type 2 diabetic patients?
Metformin
α-Glucosidase inhibitors
Gliptins (DPP-4 inhibitors)
Sulfonylureas and thiazolidinediones
All of the above
Which of the following oral antidiabetic agents cannot be used with insulin therapy in type 2 diabetic patients?
Metformin
α-Glucosidase inhibitors
Gliptins (DPP-4 inhibitors)
Sulfonylureas
None of the above
Which one of the following statements is true? Diabetic ketoacidosis:
May present as an “acute abdomen” and Is associated with 2.5% mortality in advanced health care systems
Is associated with rapid shallow respiration
Develops primarily a result of insulin resistance
Ketonuria is occasionally absent
May only present in type 1
THhe pathogenesis of hyperglycemia in diabetic ketoacidosis includes all the following mechanisms except for:
Increased glycogenolysis in the liver
Increased gluconeogenesis in the kidneys
Increased serum glucagon
Increased gluconeogenesis in adipose tissue
Decreased glucose uptake from the muscles
Which of the following symptoms/signs are included in the clinical features of diabetic ketoacidosis
Polyuria and weight loss
Tachypnea and tachycardia
Abdominal pain and vomiting
Cheyne – Stokes respiration
All of the above
A + b + c
A 35 - year - old female with diabetic ketoacidosis is admitted to the hospital with the following profile: serum glucose 412 mg/dl (22.9 mmol/L), pH 7.12, K + 4.4 mEq/L, Na + 141 mEq/L, and PO 4 3 − 2.4 mEq/L (0.77 mmol/L). Which of the following is the appropriate initial treatment?
Administration of hypotonic sodium chloride (0.45%) solution, potassium, and insulin
Administration of normal saline and insulin
Administration of normal saline, potassium, and insulin
Administration of normal saline, potassium, insulin, and bicarbonates
Administration of normal saline, insulin, and phosphate
Which of the following sentences about diabetic ketoacidosis is correct?
Administration of glucose 5% solution is prohibited
Insulin can be administered subcutaneously in all cases of diabetic ketoacidosis
Blood glucose should be measured every 3 hours after initiation of treatment
All of the above
None of the above
Which of the following statements is false?
Hyperosmolar hyperglycemic state (HHS) and diabetic ketoacidosis (DKA) can overlap in some patients
Abdominal pain is a common feature of HHS
Severe dehydration is common in HHS
Despite total body K + deficit, serum K + is usually normal or elevated at presentation in HHS
Match each of the following enzymes with the chemical reaction catalyzed by the enzyme ,Release of free fatty acids from triglyceride?
Glycogen synthase
Hormone sensitive lipase
Glycogen phosphorylase
Ketogenic enzymes
Match each of the following enzymes with the chemical reaction catalyzed by the enzyme, Production of glucose-1-phosphate from glycogen?
Glycogen synthase
Hormone sensitive lipase
Glycogen phosphorylase
Ketogenic enzymes
Match each of the following enzymes with the chemical reaction catalyzed by the enzyme, Production of acetoacetate from fatty acid?
Glycogen synthase
Hormone sensitive lipase
Glycogen phosphorylase
Ketogenic enzymes
Match each of the following enzymes with the chemical reaction catalyzed by the enzyme, Production of glycogen from glucose-1-phosphate?
Glycogen synthase
Hormone sensitive lipase
Glycogen phosphorylase
Ketogenic enzymes
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