HistaFer

Iron is an essential macronutrient that is tied to many bodily functions. Ideally, most people will meet their iron needs through diet.

True

False

There are 4 Heme groups each in every individual sub-unit of Hemoglobin.

True

False

Hemoglobin is present in all parts of the body but absent in brain due to the presence of Blood Brain Barrier.

True

False

Histidine is one of the molecule that can cross the Blood Brain Barrier.

True

False

Histidine directly bind with hemoglobin at the alpha 1 and alpha 2 chain to provide cerebral oxygenation.

True

False

HistaFer is the only product with Iron Histidine without any other combination.

True

False

Which of the follow is/are the function(s) of Iron in Brain ?

Formation of Synaptic Cleft

Regulation of Long Term Pontentiation

Transportation of oxygen to the Brain

All the Above

Which of the following is/are the function(s) of Histidine in Brain ?

It is the biosynthetic precursor of the neurotransmitter histamine (HA).

What is the main function of histidine? It's used in growth, repair of damaged tissues

Histidine is required as a precursor of carnosine in human muscle and parts of the brain

All the above

Transferrin is a glycoprotein which a __________

Helps in transportation of Histidine

Helps in the transportation of Oxygen

Helps in the transportation of Iron

Helps in the transportation of Hemoglobin

Iron affects synthesis and signaling of which neurotransmitter(s)

Dopamine

Adrenaline

Noradrenaline

All the above

The brain has a high energy demand, accounting for ________ of basal oxygen consumption

20%

45%

15%

30%

Reduced mitochondrial efficiency due to iron deficiency possibly results in elevation of ____________

Mitochondrial Dysfunction

Oxidative Stress

Hyperpolarization

Metabolic Imbalance

________ is a fatty “white matter” that insulates axons and preserves their signaling

Axon

Microglia

Astrocytes

Myelin

Iron deficiency, characterized by __________, has been associated with several developmental neurological disorders such as poorer fine and gross motor skills, visual-motor integration etc.

Glycemia

Hypoglycemia

Anemia

Hypercalcemia

Haemoglobin forms an unstable & reversible bond with __________

Nitrogen

Oxygen

Iron

Histidine

___________ form of Iron binds to Oxygen atoms with strong bond

Ferritin

Ferric

Ferrous

Ferrites

Myoglobin is composed of Single Peptide Chain that oxygen in Muscles

True

False

In co-operative oxygen binding when O2 binds to Heme group then ______ more oxygen binds with remaining heme group of the a single hemoglobin

When the Fe atom moves into the porphyrin plane after oxygenation, the ____________ histidine which is attached to the Fe is drawn closer to the Heme group.

Proximal

Distal

Both

None

Histidine is an essential ammino acid as it synthesized by the body itself.

True

False

Proximal and Distal Histidine are only 2 forms of Histidine and not separate 2 different types of Histidine.

True

False

Histidine is a Chelator of Fe & Enhances its absorption in the Haemoglobin

True

False

Histafer can also be recommended for Iron deficiency anemia

True

False

Elemental iron in HistaFer Syrup is ___________

5mg/ml

6g/ml

5g/ml

6mg/ml

What is the the function of Blood ?

Transportation of Oxygen

Transportation of Nutrition

Connection all the major organs of the body

All the above.

HistaFer

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