Metabolic kru satya
Metabolic Quiz: Understanding Lipoproteins and Heart Health
Welcome to the Metabolic Quiz! This comprehensive quiz is designed to test your knowledge on various aspects of lipoproteins, muscle tissues, and coronary artery disease (CAD). Whether you're a student, a healthcare professional, or simply someone interested in metabolic health, this quiz will provide valuable insights.
Join us to learn more about:
- Lipoprotein classifications
- Dyslipidemia and its etiology
- Fun
ctions of different muscle types - Risk factors for coronary artery disease
4. What is Lipoprotein?
A. A packaging of complex of the proteins (more polar: outer surface), known as apoproteins and the neutral lipids: unesterified cholesterol and phospholipids (inside)
B. The proteins (more polar: outer surface): the proteins components of the lipoproteins, known as apoproteins
C. The neutral lipids: unesterified cholesterol and phospholipids (inside)
5. How many classes of plasma lipoproteins?
A. Apolipoproteins
B. Size
C. Lipid composition
D. Color
E. a, b & c
6. What are the functions of Lipoprotein?
A. Transport of lipids from the liver
B. Absorption and transport of dietary lipids by the small intestine
C. Transport of lipids to peripheral tissues to the liver and intestine (reverse cholesterol transport)
D. Transport toxic foreign hydrophobic and amphipathic compounds such bacterial endotoxin
E. Synthesis protein
F. a, b, c & d
7. What are the functions of Apolipoprotein?
B. Serving as activators of inhibitors of enzymes involved in the metabolism lipoproteins c. Serving a structural role
E. Serve as a DNA
F. a, b, c & d
8. What are the classification methods for Lipoproteins?
A. Electrophoresis
C. Ultracentrifugation
D. a & c
9. Give 5 examples of lipoproteins?
Chylomicron
C. HDL
G. a, b, c, d & e
10. Give 4 example to check plasma lipid profiles?
D. Total cholesterol
E. Apo-B level: measure of LDL-cholesterol (bad)
H. All of the above
11. When should check lipid profile?
A. All patients with diabetes mellitus, at least once in 6 months
D. All person above 40, should be checked once in a year
E. All of the above
12. What are the etiology of Dyslipidemia?
A. Primary: Family or genetic
B. Secondary: Due to other diseases
C. a & b
13. What is clinical features of hyperlipidemia?
E. b, c & d
B. Xanthomas
C. Pancreatitis
D. No clinical manifestations an atherosclerotic vascular events
14. What are the risk factors of CAD?
B. High cholesterol
D. Family history
F. Atherosclerosis
I. a, b, c, d, e, f, & g
15. Give 3 examples of Hypolipidemic Drugs?
A. HMGCoA reductase inhibitors (“statins”)
B. Bile acid binding resins (Cholestyramine and Cholestipol): reduced reabsorption of bile acids
C. Fibrate
E. a, b & c
16. What is Coronary Artery disease (CAD)?
A. The pathologic process affecting the coronary arteries (usually atherosclerosis). Also known as Coronary heart disease (CHD)= Coronary artery disease (CAD) or ischemic heart disease (IHD).
B. The pathologic process (usually atherosclerosis) affecting the entire arterial circulation, not just the coronary arteries.
17. What are the 4 major primary tissue?
A. Muscle tissue
C. Epithelial tissue
E. Blood tissue
B. Nervous tissue
F. a, b, c & d
18. What is the 3 types of muscle tissues?
A. Cardiac muscle
B. Smooth muscle
C. Skeletal muscle
E. a, b & c
19. Give the actions of skeletal muscle.
A. Depression: moves insertion downward
D. Rotator: Rotates a bone along its axis
I. All the above
20. Describe the structure of skeletal muscle?
A. Distinctive feature: striated appearance (alternating dark and light bands), The light bands are called I bands (isotropic)
B. Muscle fascicle (cell): composed of many muscle fibers, or myofibers (1micrometer) in diameter, surrounded by a plasma membrane or sarcolemma, densely packed that other organelles, enveloped by a thin connection tissue layer (endomysium)
C. Skeletal muscle fibers are multinucleate- multiple nuclei
E. a, b & c
21. What is Motor Unit?
B. Is the nerve only
C. Consists of a somatic motor neuron and the muscle fibers it innervates d. Is the skeletal muscle only.
A. All the correct
22. What is Cross-bridges?
A. Cross bridges that extend from the thick to the thin filaments cause sliding of the filaments, and thus muscle tension and shortening
B. The availability of Ca2+ increase action potentials in muscle fiber
D. In the context of muscular contraction, a cross-bring refers to the attachment of myosin with actin within the muscle cell. All muscle types – whether we’re talking about skeletal, cardiac, or smooth-contract by cross-bridge cycline- that is, repeated attachment of actin and and myosin within the cell
F. a, b & d
23. Please choose the best description “When the muscle contracts”
F. a, b, c & d
A. Sarcomeres decrease in length
B. Shortening of its individual fibers
C. Shorting their myofibrils
D. Shortening of the distance from Z disc to Z disc
24. What are the energy requirements of skeletal muscles?
A. At rest obtain most of their energy from the aerobic respiration of fatty acids
B. During exercise: muscle glycogen and blood glucose
C. Obtain energy mainly from protein catabolism
25. What is Phosphocreatine?
A. Phosphocreatine, also known as creatine phosphate (CP) or PCr (Pcr), is a phosphorylated creatine molecule that serves as a rapidly mobilizable reserve of high energy phosphates in skeletal muscle, myocard and the brain to recycle adenosine triphosphate, the energy currency of the cell.
B. Phosphocreatine serves as a muscle reserves of high-energy phosphates, used for the rapid formation of ATP. These reactions are catalyzed by creatine phosphokinase (CPK).
C. The enzyme that transfers phosphate between creatine and ATP is called creatine kinase, or creatine phosphokinase.
26. Give a structure feature of cardiac muscle?
A. Cardiac muscle can produce impulse and contract spontaneously
B. The myocardial cells are short, branched, tubular in structure and interconnected c. Each myocardial cell is joined to adjacent myocardial cells by electrical synapses, or gap junctions
D. The gap junctions permits electrical impulse to be conducted primarily along the long axis from cell to cell
F. a, b, c & d
27. What are the troponin complex of Cardiac muscle?
A. Troponin I helps inhibit the binding of the myosin cross bridges to actin b. Troponin T binds to tropomyosin in the thin filaments
C. Troponin c binds to Ca2+ for muscle contraction
D. Cardiac muscle has no Troponin as Skeletal muscle
E. a, b & c
28. What are the structure property of smooth muscle?
A. Smooth (visceral) muscles are arranged in the circular layers in the walls: the blood vessels and bronchioles (small air passages in the lungs) and the tubular digestive tract, the ureters (which transports sperm cells), and the uterine tubes (which transports ova). b. Not contain sarcomeres
C. Contain a great deal of actin (thin) and some myosin (thick): Ratio of thin/thick filaments =16/1 (in striated muscles the ratio is 2/1)
F. Troponin, however, is not present in smooth muscle cells
h. All of the above
29. What are the 2 fundamental function of heart?
A. They are designed to perform two fundamental functions: initiation and conduction of electrical impulses, contraction
B. Only for contraction function
30. What are the two conduction tissue of the heart?
A. The sinus node (sinoatrial node) and the atrioventricular node
B. Somatic motor neuron
31. What is Coronary Artery disease (CAD)?
A. The pathologic process affecting the coronary arteries (usually atherosclerosis), Also known as Coronary heart disease (CHD)= Coronary artery disease (CAD) or ischemic heart disease (IHD)
B. The pathologic process (usually atherosclerosis) affecting the entire arteries circulation, not just the Coronary arteries
32. What are the risk factors for CAD?
A. Smoking, high cholesterol, hypertension, atherosclerosis, diabetes, obesity, family history and stress
B. None of above
33. What are the two main symptomatic classification of ischemic heart disease?
A. Clinically silent and symptomatic (Stable angina and acute coronary syndromes)
b. Asymptomatic only
C. Clinically silent only (Stable angina and acute coronary syndromes)
34. What is stable angina?
A. Clinical manifestations of angina are very variable such as discomfort in the chest, jaw, shoulder, back, or arms. Symptoms got worse by exertion or emotional stress (climbing hills or stairs) and relieved by rest or nitroglycerin (vasodilation of coronary artery). Sometime can be mistaken as indigestion. For Diabetics/elderly patient do not have symptom (silent ischaemia), has only breathlessness or fatigue.
B. Ischaemia heart disease that never have any symptoms such as chest pain on heavy exercise and climbing the stair or mountain.
35. What is Acute coronary syndrome (ACS)?
A. Acute coronary syndrome is a term used to describe a range of conditions associated with sudden, reduced blood flow to the heart and symptoms of chest pain which is not, or only partially, relieves by GTN. All patients with ACS should be evaluation, risk stratification and treatment.
B. Acute coronary syndrome is asymptomatic
36. Choose the correct for established Cardiac markers?
A. Troponin I and Troponin T, Creatine kinase (CK-MB), and myoglobin
b. Liver function test such as AST/ALT
37. What is Cardiac Arrhythmia?
A. Arrhythmia is an abnormality of the cardiac rhythm is called a cardiac arrhythmia which can cause sudden death, syncope, heart failure, chest pain, dizziness, palpitations. Sometime produced no symptoms at all. The cause of arrhythmia can be originated from normal hearts vs diseased tissue.
B. Normal heart rate contraction
C. Arrhythmia produces no sign and symptoms in every types of diseases.
38. Give the 2 main classification of Arrhythmia?
A. There are two main types of arrhythmia: Bradycardia: the heart rate is slow (<60 b.p.m. During the day or <50 b.p.m. At night), Trachycardia: the heart rate is fast (>100 b.p.m.) b. Bradycardia alone
C. Trachycardia alone
D. Supraventricular Trachycardias
39. What is Cardiomyopathies?
A. A group of disease of the myocardium that affect the mechanical or electrical function of the heart
B. Heart failure only and no other sign and symptoms
40. Give the classification of myopathies with systemic disorders
B. Inflammation myopathies
D. Myopathy from infectious disease
G. Metabolic myopathies
H. All the above
41. What is Troponin?
A. Troponin: a complex of three proteins (work with troponin and act as a switch: Troponin I ( which inhibits the binding of the cross bridges to actin), Troponin T (which binds to tropomyosin), Troponin C ( which binds Ca2+)
B. Troponin is not contain in skeletal and cardiac muscle
C. Troponin is part of thick filament or myosin
42. Please choose the best description of the two types of myofibril?
C. The thick filaments are primarily composed of the protein myosin
A. The A bands: thick filaments (dark)
D. The thin filaments are primarily composed of the protein actin
F. a, b, c & d
43. What is Epithelial tissue?
A. Epithelial tissue consists of muscle cells that cause a contraction of muscle b. Epithelial tissue consists of cells that is not form membrane and not contain in the glands
C. Epithelial tissue consists of cells that form membranes, which cover and line the body surfaces, and of gland.
44. How many categories of glands?
A. There is only one categories of gland: Endocrine glands
B. There is only one categories of gland: Exocrine glands
C. There are 2 categories of gland: Exocrine glands and Endocrine glands.
45. Choose the best describe of Exocrine gland?
A. Exocrine glands is not secrete chemicals called hormones into the blood.
B. Exocrine glands ( G.exo= outside) secrete chemicals through a duct that leads to the outside of a membrane, and thus to the outside of a body surface.
C. Exocrine glands secrete chemicals called hormones into the blood.
46. Choose the best describe of endocrine gland?
A. Endocrine gland(G.endo= within) secrete chemicals called hormones into the blood.
. c. Endocrine glands secrete chemicals through a duct that leads to the outside of membrane and thus to the outside of a body surface.
B. Endocrine glands is not secrete chemicals called hormone into the blood
47. What are the five general function of endocrine gland?
A. Not involve in all maintenance of an optimal internal environment throughout the life span.
B. Coordination of the male and female reproductive systems with make sexual reproduction possible
C. Initiation of corrective and adaptive responses with emergency demands occur
d. There are five general functions of endocrine glands 1. Differentiation of the reproductive and central nervous systems in the developing fetus 2. Stimulation of sequential growth and development during childhood and adolescence 3. Coordination of the male and female reproductive system which makes sexual reproduction possible 4. Maintenance of an optimal internal environment throughout the life span 5. Initiation of corrective and adaptive responses when emergency demand occur. e. Initiation of corrective and adaptive response when emergency demand occur.
48. Choose some example of endocrine glands?
A. Eye, sweat gland , salivary glands
B. Muscle , bone , blood , and tendon
C. Pineal body, hypothalamus, pituitary gland , parathyroid gland , Thyroid gland, thymus, adrenal gland , pancreas , testes and ovary.
49. Choose the correct answer for non-endocrine body systems/organs?
a. Muscle, bone , blood, and tendon
B. Eye ,sweat, gland, salivery glands
C. Heart, kidneys, adipose tissue, stomach, liver
50. What are the 3 classification hormone actions?
A. Parcrine: between local cells
B. Endocrine: between cells located remotely from each other.
C. Hormone action can be classified into:1. Autocrine: mechanisms of communication and control occur within a cell, 2. Paracrine: between local cells, 3: Endocrine : between cells located remotely from each other.
51. What is th similarity of Neurotransmitters and hormones?
A. The same molecule can be both a hormone and a neurotransmitter and there is also overlap between the function of endocrine glands and the nervous system (neurotransmitters)
B. The hormone and neurotransmitter secrete have no any similarity in term functions
C. The hormone and neurotransmitter secrete form the same cells
52. What is the hormone general characteristics?
A. Has specific rates and rhythms of secretion only
B. 1. Has specific rates and rhythms of secretion 2. Operate within feedback systems 3. Affect only cells with appropriate receptors and then act on those cells to initiate specific cell functions or activities, and 4. Steroid hormones are either excreted directly by the kidneys or metabolized (conjugated) by the liver
C. Operate within feedback systems only
53. What are the classification of hormones?
A. Based on gland of origin only
B. Based structure only
C. Based on 1. Structure 2. Chemical composition 3. Gland of origin
1. What are the 4 major biomolecules in life?
A. Protein: meat, enzyme
B. Nucleic acids: DNA, RNA
C. Carbohydrate: Glucose, starch
D. Lipid: fat, cholesterol
E. Muscle
F. a, b, c & d
2. What is lipid?
A. Relatively insoluble in water
B. Free soluble in non-polar organic solvents
C. Consists of a different group of biochemical important compound
D. Free soluble in water
E. a, b & c
3. What is lipid classification based on its chemical nature?
A. Compound lipids
B. Derived lipid
C. Simple lipids
D. Lipid complexes to other compounds
E. Triglyceride
F. a, b, c & d
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