L-03-01-P29 - Introduction to Cancer
Introduction to Cancer Quiz
Test your knowledge and understanding of cancer biology with our engaging quiz! This quiz covers various aspects of cancer development, cell cycle regulation, and differentiation. Suitable for students and enthusiasts alike, it allows you to learn while having fun.
- Over 15 questions on cancer-related topics
- Multiple choice and checkbox formats
- Gain insights into the cell cycle, apoptosis, and tumor formation
1. Which of the following is correct regarding the cell cycle (more than 1 answer)?
A. Cell cycle is tightly regulated
B. Cell cycle is dictated by length of telomeres
C. At G1 – numerous proteins control whether the cell can continue onto S phase
D. Cell division is controlled by nutrient availability
E. Cells can respond to external signals to enter the cell cycle
2. Which of the following is not a function of growth factors?
A. Cell migration
B. Cell death
C. Cell growth
D. Cell differentiation
E. Cell lineage
3. During the G0 phase, cells may permanently exit the cell cycle
True
False
4. Which of the following is correct about cell differentiation?
A. Cells can leave the cell cycle through differentiation
B. Cancer cells can fully differentiate
C. Cell differentiation causes formation of zona pletra
D. Undifferentiated cells are essentially immortal
E. No external signals are required for cells to undergo differentiation
5. Every type of cancer is different
True
False
6. Apoptosis:
A. Is unregulated in mammals
B. Is inactive in cancer cells
C. Is inactive in undifferentiated cells
D. Is a requirement for cancer cells to grow
E. Is less likely to occur when there is significant DNA damage
7. Telomeres:
A. Are found in all organisms
B. Are strongly linked to ageing in cancer cells
C. Can be reconstructed in cancer cells
D. Are not found in embryonic stem cells
E. Can reconstruct themselves independently
8. A growing mass of cancer cells is known as:
A. Carcinome
B. Malignatome
C. Tumour
D. Cell Mass
E. Deformed Growth Mass
9.Increased organ size from cancer can be lethal because:
A. It may lead to failure of the organ due to essential enzymes not being able to enter
B. It may lead to failure of the organ due to reduced immunity
C. It may lead to failure of the organ as the cancer cells may enlarge and squash neighbouring healthy cells
D. The organ may begin to protrude from the body
E. The organ would be unable to produce chondriol for surrounding tissue
10. Essential proteins often check the cell for errors at the G1/S phase boundary. While ________________ can halt the cell cycle, __________can also check DNA for errors as well as regulate apoptosis.
A. Retinoblastoma, p53
B. Retinoblastoma, Cytosaline
C. Oncogenes, p53
D. p53, Retinoblastoma
E. Retinoblastoma, G-breaker transferase
11. Tumour formation can result from:
A. Chemical exposure
B. Diet
C. Exposure to benzopyrene
D. Errors in signalling the end of cell division
E. Stem cells failing to produce one non-stem cell daughter
F. Daughter cells failing to differentiate
G. All of the above
12. Internalising over-expressed surface cell receptors can:
A. Cause the cell to lyse
B. Be effective treatment for breast cancer
C. Cause the cell to undergo apoptosis
D. Be a potential cause of cancer
E. Stimulate production of growth factors
13. Tumours are masses of cells derived from a single cell.
True
False
14. Cancers progress from ________________ to ________________, and finally to ________________
A. A single cell mutation, tumour, metastasis
B. Metastasis, a single cell mutation, tumour
C. Single cell mutation, carcinoma, tumour
D. Tumour, carcinoma, metastasis
E. Metastasis, tumour, carcinoma
15. Cancer cells need to be able to communicate with surrounding healthy cells and the ECM to grow.
True
False
16. Which of the following is incorrect?
A. Contact inhibition of growth is present in normal cells but absent in cancer cells
B. Anchorage-dependence is observed in normal cells but not in cancer cells
C. Normal cells have high growth factor requirement while cancer has low growth factor requirement
D. Karyotype profiling is abnormal in cancer cells
E. Cell cycle checkpoints are intact in normal cells but not in cancer
F. Cancer cells have a definite proliferative life span (i.e. They are not immortal)
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