USS DES Test 13A (Start from page 1936)
1) A 32-year-old female presents with intermittent blood staining of her bra from her left breast. She has not felt any lumps on either breast. Physical examination shows no breast mass or axillary lymphadenopathy. Ultrasonogram of the breast is within normal limits. Which of the following is the most likely diagnosis?
Fibrocystic changes
Fibroadenoma
Intraductal papilloma
Ductal carcinoma in situ
Hyperprolactinemia
2) A 68-year-old man is brought to the emergency department following a high-speed automobile accident. He is alert and complains of chest pain and mild back pain. His blood pressure is 80/60 mm Hg. Chest x-ray shows a widened mediastinum, tracheal deviation, bronchial displacement, and loss of the aortic knob. Which of the following is the most likely diagnosis?
Cardiac tamponade
Myocardial contusion
Pulmonary contusion
Tension pneumothorax
Traumatic aortic rupture
3) A 35-year-old man comes to the physician because of persistent dull perineal pain and dysuria for 6 months. The patient denies urinary tract infections or urethral discharge. His temperature is 37 C (98.6 F). On digital rectal examination, the prostate is slightly tender and boggy but not enlarged or indurated. Urinalysis is normal. Expressed prostatic secretions show the following: Leukocytes 30 cells/high power field Bacteria None Cultures of prostatic secretion and urine are negative for bacteria. Which of the following is the most likely diagnosis?
Acute cystitis
Acute prostatitis
Chronic bacterial prostatitis
Chronic nonbacterial prostatitis
Prostatodynia
4) A 56-year-old man has been having bloody bowel movements on and off for the past several weeks. He reports that the blood is bright red, it coats the outside of the stools, and he can see it in the toilet bowl even before he wipes himself. When he does so, there is also blood on the toilet paper. After further questioning, it is ascertained that he has been constipated for the past 2 months and that the caliber of the stools has changed. They are now pencil thin, rather the usual diameter of an inch or so that was customary for him. He has no pain. Which of the following is the most likely diagnosis?
Anal fissure
Cancer of the cecum
Cancer of the rectum
External hemorrhoids
Internal haemorrhoids
5) A front-seat passenger in a car involved in a head-on collision relates that he hit the dashboard with his knees, however, he is specifically complaining of severe pain in his right hip, rather than knee pain. He lies in the stretcher in the emergency department with the right lower extremity shortened, adducted, and internally rotated. Which of the following is the most likely injury?
Femoral neck fracture
Fracture of the shaft of the femur
Intertrochanteric fracture
Posterior dislocation of the hip
Posterior dislocation of the knee
6) An 81-year-old man with Alzheimer disease who lives in a nursing home undergoes surgery for a fractured femoral neck. On the 5th postoperative day, it is noted that his abdomen is grossly distended and tense, but not tender. He has occasional bowel sounds. The rectal vault is empty on digital examination, and there is no evidence of occult blood. X-ray films show a few distended loops of small bowel and a much distended colon. The cecum measures 9 cm in diameter, and the gas pattern of distention extends throughout the entire large bowel, including the sigmoid and rectum. No stool is seen in the films. Other than the abdominal distention, and the ravages of his mental disease, he does not appear to be ill. Vital signs are normal for his age. Which of the following is the most likely diagnosis?
Fecal impaction
Mechanical intestinal obstruction
Ogilvie syndrome
Paralytic ileus
Volvulus of the sigmoid colon
7) A 55-year-old, HIV-positive man has a fungating mass growing out of the anus. He can feel it when he wipes himself after having a bowel movement, but it is not painful. For the past 6 months, he has noticed blood on the toilet paper, and from time to time there has also been blood coating the outside of the stools. He has lost weight, and he looks emaciated and ill. On physical examination, the mass is easily visible. It measures 3.5 cm in diameter, is fixed to surrounding tissues, and appears to grow out of the anal canal. He also has rock-hard, enlarged lymph nodes on both groins, some of them as large as 2 cm in diameter. Which of the following is the most likely diagnosis?
Adenocarcinoma of the rectum
Condyloma acuminata of the anus
External hemorrhoids
Rectal prolapse
Squamous cell carcinoma of the anus
8) A 79-year-old man with atrial fibrillation develops an acute abdomen. When seen 2 days after the onset of the abdominal pain, he has a silent abdomen, with diffuse tenderness and mild rebound. There is a trace of blood on the rectal examination. He also has acidosis and looks quite sick. X-ray films show distended small bowel and distended right colon, up to the middle of the transverse colon. Which of the following is the most likely diagnosis?
Acute pancreatitis
Mesenteric ischemia
Midgut volvulus
Perforated viscus
Primary peritonitis
9) After a grand mal seizure, a 32-year-old epileptic woman notices pain in her right shoulder, and she cannot move it. She goes to a minor emergency clinic, where she has a limited physical examination and anteroposterior (AP) x-ray films of her shoulder. The films are read as negative, and she is diagnosed as having a sprain and given pain medication. The next day, she still has the same pain and is unable to move her arm. She comes to the emergency department holding her arm close to her body, with her hand resting on her anterior chest wall. Which of the following is the most likely diagnosis?
Acromioclavicular separation
Anterior dislocation of the shoulder
Articular cartilage crushing
Posterior dislocation of the shoulder
Torn teres major and minor muscles
10) A 54-year-old woman is brought to the emergency department after a head-on automobile accident. On arrival, she is breathing well. She has multiple bruises over the chest and multiple sites of point tenderness over the ribs. X-ray films show multiple rib fractures on both sides, but the lung parenchyma is clear, and both lungs are expanded. Two days later she is in respiratory distress, and her lungs "white out" on repeat chest x-ray films. Which of the following is the most likely diagnosis?
Flail chest
Myocardial contusion
Pulmonary contusion
Tension pneumothorax
Traumatic rupture of the aorta
11) A previously healthy 55-year-old man undergoes elective right hemicolectomy for a stage I (T2N0M0) cancer of the cecum. His postoperative ileus is somewhat prolonged, and on the fifth postoperative day his nasogastric tube is still in place. Physical examination reveals diminished skin turgor, dry mucous membranes, and orthostatic hypotension. Pertinent laboratory values are as follows:Arterial blood gases: pH 7.56, PCO2 50 mm Hg, PO2 85 mm Hg.Serum electrolytes (mEq/L): Na+ 132, K+ 3.1, Cl- 80; HCO3- 42.Urine electrolytes (mEq/L): Na+ 2, K+ 5, Cl- 6What is the patient’s acid–base abnormality?
Uncompensated metabolic alkalosis
Respiratory acidosis with metabolic compensation
Combined metabolic and respiratory alkalosis
Metabolic alkalosis with respiratory compensation
Mixed respiratory acidosis and respiratory alkalosis
12) A 65-year-old man undergoes a low anterior resection for rectal cancer. On the fifth day in hospital, his physical examination shows a temperature of 39°C (102°F), blood pressure of 150/90 mm Hg, pulse of 110 beats per minute and regular, and respiratory rate of 28 breaths per minute. A computed tomography (CT) scan of the abdomen reveals an abscess in the pelvis. Which of the following most accurately describes his present condition?
Systemic inflammatory response syndrome (SIRS)
Sepsis
Severe sepsis
Septic shock
Severe septic shock
13) A 24-year-old man comes to the physician 24 hours after sustaining an injury to the right knee while playing soccer. He can walk, but he limps on the right side. He reports that he was hit by another player on the lateral side of his right knee, but did not feel a snap or pop at the time of the accident. On examination, the right knee appears normal, but palpation elicits tenderness along the medial aspect of the joint line. Increased laxity is observed when a valgus stress is applied to the knee flexed at 30 degrees, but not when the knee is in full extension. Lachman's test and posterior drawer tests are negative. Which of the following is the most likely diagnosis?
Meniscus injury
Sprain of the lateral collateral ligament
Sprain of the medial collateral ligament
Tear of the anterior cruciate ligament
Tear of the posterior cruciate ligament
14) A 35-year-old man had a splenectomy 8 days ago, following a motor vehicle accident. He is now complaining of left shoulder pain. His temperature is 39.0C (102.2F), blood pressure is 110/80 mm Hg, pulse is 110/min, and respirations are 30 min and shallow, Physical examination shows clear lungs with equal breath sounds bilaterally and mild tenderness to palpation in the left upper quadrant with a well-healing midline laparotomy incision. Laboratory studies show: Hemoglobin 15 g/dL, Hematocrit 45%, Leukocyte counts 15,000/mm3.A chest x-ray film shows no infiltrates or effusions. Which of the following is the most likely diagnosis?
Left clavicle fracture
Left lower lobe pneumonia
Post-splenectomy sepsis
Subphrenic abscess
Subphrenic hematoma
15) A 27-year-old man is shot point blank with a .22-caliber revolver. The entrance wound is in the anterior chest wall, just to the left of the sternal border, at the level of the 4th intercostal space. There is no exit wound. He is diaphoretic, cold, shivering, and anxious, and is asking for a blanket and a drink of water. His blood pressure is 65/40 mm Hg, and his pulse is 145/min and barely perceptible. He has large, distended veins in his neck and forehead. He is breathing adequately and has bilateral breath sounds. He is neurologically intact. Which of the following is the most likely diagnosis?
Extrinsic cardiogenic shock due to pericardial tamponade
Extrinsic cardiogenic shock due to tension pneumothorax
Hemorrhagic shock
Intrinsic cardiogenic shock due to myocardial damage
Vasomotor shock
16) A 61-year-old alcoholic man presents with severe epigastric pain radiating to his back. His amylase and lipase are elevated, and he is diagnosed with acute pancreatitis. Over the first 48 hours, he is determined to have 6 Ranson’s criteria, including a PaO2 less than 60 mm Hg. His chest x-ray reveals bilateral pulmonary infiltrates, and his wedge pressure is low. Which of the following criteria must be met to make a diagnosis of adult respiratory distress syndrome (ARDS)?
Hypoxemia defined as a PaO2/FiO2 ratio of less than 200
Hypoxemia defined as a PaO2 of less than 60 mm Hg
A pulmonary capillary wedge pressure greater than 18 mm Hg
Lack of improvement in oxygenation with administration of a test dose of furosemide
Presence of a focal infiltrate on chest x-ray
P1941 Q17
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17) A 60-year-old woman presents with the skin lesion shown here. She reports a history of a burn injury to the hand while cooking a few years ago. She reports the wound has never healed completely. You are concerned about the skin lesion and perform a punch biopsy. Which of the following is the most accurate diagnosis given the patient’s history? |
Basal cell carcinoma
Malignant melanoma
Erythroplasia of Queyrat
Bowen disease
Marjolin ulcer
18) A 31-year-old accounting student presents with a persistent headache that began approximately 4 months ago. The headache has been gradually increasing in intensity, and is worse in the mornings. Thinking that she might need new glasses, she sought help from her optometrist, who discovered that she has bilateral papilledema and sent her in for medical evaluation. On direct questioning, she admits to repeat vomiting for the past 3 weeks, with no heaving, straining, or preceding nausea. "I would just open my mouth, and the stuff would hit the wall," she explains. She denies any other neurological symptoms. Which of the following is the most likely diagnosis?
Brain abscess
Brain tumor
Chronic subdural hematoma
Multiple sclerosis
Subarachnoid bleeding
19) A brain-dead potential donor has become available. You must plan for the dispersal of the thoracic organs. Which of the following will necessitate a heart-lung transplant? .
Primary pulmonary hypertension
Cystic fibrosis
End-stage emphysema
Idiopathic dilated cardiomyopathy with long-standing secondary pulmonary hypertension
End-stage pulmonary fibrosis secondary to sarcoidosis
20) A 55-year-old woman who has end-stage liver disease is referred to a hepatologist for evaluation. Which of the following would prevent her from being a transplantation candidate?
Use of alcohol 3 months ago
Two 2-cm hepatocellular carcinomas (HCCs) in the right lobe of the liver
A 4-cm hepatocellular carcinoma in the right lobe of the liver
Development of hepatorenal syndrome requiring hemodialysis
History of breast cancer 5 years ago with no evidence of disease currently
21) A 55-year-old woman requires an abdominoperineal operation for rectal cancer. She has a history of stable angina. Which of the following clinical markers is most likely to predict a cardiac event during her noncardiac surgery and should prompt further cardiac workup prior to her operation?
Abnormal electrocardiogram
Prior stroke
Unstable angina
Uncontrolled hypertension
Her age
22) An 18-year-old man was traveling at a high speed when his car slammed into a wall. He is brought into the emergency department by ambulance. His blood pressure is 60/40 mmHg, pulse is 115/min and weak, respirations are 18/min, and central venous pressure is 2 cmH2O. He is responsive only to painful stimuli. Breath sounds are equal bilaterally, and cardiac auscultation reveals only tachycardia. The abdomen is soft, nondistended, and nontender with active bowel sounds. A chest x-ray film shows a widened mediastinum. Which of the following is the most likely diagnosis?
Cardiac contusion
Cardiac tamponade
Flail chest
Ruptured thoracic aorta
Tension pneumothorax
23) A 22-year-old woman is taken to the emergency department after she injures her foot. She had been standing on a chair changing a light bulb, when she accidentally stepped off the chair backward. She heard a cracking sound when she fell and developed pain and swelling behind the ankle. Her symptoms worsened when she tried to descend the stairs in her house. Physical examination demonstrates marked swelling behind her ankle, and her pain is exacerbated by plantar flexion and dorsiflexion of the hallus. Which of the following is the most likely diagnosis?
Anterior Achilles tendon bursitis
Calcaneal spur syndrome
Epiphysitis of the calcaneus
Fracture of the posterolateral talar tubercle
Posterior tibial nerve neuralgia
24) A 60-year-old man complains of anal itching and discomfort, particularly toward the end of the day. He works as a salesman in a department store, where he has to be on his feet all day. When he goes home in the evening, he finds himself sitting sideways to avoid the discomfort. He has no fever, rectal bleeding, or soiling of his underwear, and he has never had surgery in that area. Which of the following is the most likely diagnosis?
Anal fissure
External hemorrhoids
Fistula in ano
Internal hemorrhoids
Perirectal abscess
25) A 71-year-old man develops dysphagia for both solids and liquids and weight loss of 60 lb over the past 6 months. He undergoes endoscopy, demonstrating a distal esophageal lesion, and biopsies are consistent with squamous cell carcinoma. He is scheduled for neoadjuvant chemoradiation followed by an esophagectomy. Preoperatively he is started on total parenteral nutrition, given his severe malnutrition reflected by an albumin of less than 1. Which of the following is most likely to be a concern initially in starting total parenteral nutrition in this patient?
Hyperkalemia
Hypermagnesemia
Hypoglycemia
Hypophosphatemia
Hypochloremia
26) A 38-year-old woman who underwent a cadaveric renal transplant 8 years ago presents with fevers, fatigue, and weight loss. Evaluation included CT scans of the head, neck, chest, abdomen, and pelvis; she is noted to have diffuse lymphadenopathy and pulmonary nodules. A biopsy and histologic examination of a lymph node is performed. Which of the following viruses is most likely to be present in the lymph node?
Cytomegalovirus
Human papillomavirus
Human herpesvirus 8
Epstein-Barr virus
Coxsackie virus
27) An elderly diabetic woman with chronic steroid-dependent bronchospasm has an ileocolectomy for a perforated cecum. She is taken to the ICU intubated and is maintained on broad-spectrum antibiotics, renal dose dopamine, and a rapid steroid taper. On postoperative day 2, she develops a fever of 39.2°C (102.5°F), hypotension, lethargy, and laboratory values remarkable for hypoglycemia and hyperkalemia. Which of the following is the most likely explanation for her deterioration?
Sepsis
Hypovolemia
Adrenal insufficiency
Acute tubular necrosis
Diabetic ketoacidosis
28) On postoperative day 5, an otherwise healthy 55-year-old man recovering from a partial hepatectomy is noted to have a fever of 38.6°C (101.5°F). Which of the following is the most common nosocomial infection postoperatively?
Wound infection
Pneumonia
Urinary tract infection
Intra-abdominal abscess
Intravenous catheter-related infection
29) A 42-year-old man has had a rocky course for the 3 days following a bowel resection for intestinal perforation due to inflammatory bowel disease. His CVP had been 12 to 14 but is now 6, in the face of diminished blood pressure and oliguria. Which of the following is the most likely etiology of his hypotension?
Pulmonary embolism
Hypervolemia
Positive-pressure ventilation
Pneumothorax
Gram-negative sepsis
30) Acute renal failure occurs following aortic angiography in a 72-year-old man. His weight has been rising, his lungs show rales at both bases, and he is dyspneic. His fractional excretion of sodium is greater than 1. He has eosinophilia on his peripheral smear, an elevated erythrocyte sedimentation rate, and proteinuria with microscopic hematuria. Which of the following is the most likely cause of his renal failure?
Hypovolemia
Renal artery cholesterol embolism
Acute tubular necrosis
Cardiogenic shock
Aortic dissection
31) A 26-year-old man is resuscitated with packed red blood cells following a motor vehicle collision complicated by a fractured pelvis and resultant hemorrhage. A few hours later the patient becomes hypotensive with a normal central venous pressure (CVP), oliguric, and febrile. Upon examination, the patient is noted to have profuse oozing of blood from his intravenous (IV) sites. Which of the following is the most likely diagnosis?
Hypovolemic shock
Acute adrenal insufficiency
Gram-negative bacteremia
Transfusion reaction
Ureteral obstruction
32) A 72-year-old man undergoes a subtotal colectomy for a cecal perforation due to a sigmoid colon obstruction. He has had a prolonged recovery and has been on total parenteral nutrition (TPN) for 2 weeks postoperatively. After regaining bowel function, he experienced significant diarrhea. Examination of his abdominal wound demonstrates minimal granulation tissue. He complains that he has lost his taste for food. He also has increased hair loss and a new perioral pustular rash. Which of the following deficiencies does he most likely have?
Zinc
Selenium
Molybdenum
Chromium
Thiamine
33) A patient develops a fever and tachycardia during a blood transfusion after a redo coronary artery bypass procedure. The nurse subsequently discovers that there was a mix-up in the cross-match because of a labeling error. Which of the following is diagnostic in a patient with an immediate hemolytic reaction secondary to a blood transfusion?
Serum haptoglobin above 50 mg/dL
Indirect bilirubin greater than 5 mg/dL
Direct bilirubin greater than 5 mg/dL
Positive Coombs test
Myoglobinuria
34) An obese 50-year-old woman undergoes a laparoscopic cholecystectomy. In the recovery room, she is found to be hypotensive and tachycardic. Her arterial blood gases reveal a pH of 7.29, PaO2 of 60 mm Hg, and PaCO2 of 54 mm Hg. Which of the following is the most likely cause of this patient’s problem?
Acute pulmonary embolism
Carbon dioxide (CO2) absorption from induced pneumoperitoneum
Alveolar hypoventilation
Pulmonary edema
Atelectasis from a high diaphragm
35) Approximately 6 weeks following a kidney transplant, a 59-year-old woman develops fever, malaise, and myalgias and is found to have a cytomegalovirus (CMV) infection. Which of the following is a potential sequela of CMV infection?
Pyelonephritis
Gastrointestinal (GI) ulceration and haemorrhage
Cholecystitis
Intra-abdominal abscess
Parotitis
36) A 24-year-old woman develops moderate, generalized abdominal pain of sudden onset and shortly thereafter faints. At the time of evaluation in the emergency department, she has regained consciousness, is pale, and has a blood pressure of 95/70 mm Hg and a faint pulse rate of 90/min. The abdomen is mildly distended and tender, with normal bowel sounds. Her hemoglobin is 7 g/dL. There is no history of trauma, but it is suspected that she might be bleeding into her abdomen, and a diagnostic peritoneal lavage is performed. The study shows that there is free blood in the peritoneal cavity. She denies the possibility of pregnancy because she has been on birth control pills since the age of 14 and has never missed taking them. Pelvic examination is normal, and a pregnancy test is negative. At laparotomy, the surgeons are likely to find which of the following?
Bleeding ovarian follicle
Ruptured abdominal aortic aneurysm
Ruptured ectopic pregnancy
Ruptured hepatic adenoma
Ruptured hepatic artery aneurysm
37) A 42-year-old man is undergoing chemotherapy after resection of a cecal adenocarcinoma with positive lymph nodes. You are asked to see him regarding a potential surgical complication. Which of the following potentially operable complications is a common occurrence among patients receiving systemic chemotherapy?
Acute cholecystitis
Perirectal abscess
Appendicitis
Incarcerated femoral hernia
Diverticulitis
38) A 30-year-old previously healthy man presents with refractory hypertension on four medications. Urinalysis is positive for metanephrines. He was adopted as an infant and therefore does not know his family history. Which of the following inherited syndromes is not associated with this disease?
MEN2A
MEN2B
Von Hippel-Lindau disease
Neurofibromatosis II
Neurofibromatosis I
39) A 55-year-old man is diagnosed with benign prostatic hyperplasia. The patient declines pharmacologic treatment and elects to undergo transurethral resection of the prostate (TURP). Which of the following is the most common complication of this procedure?
Bladder neck contracture
Impotence
Incontinence
Recurrence of symptoms
Retrograde ejaculation
40) A 22-year-old healthy African-American woman presents with a recurrent growth on her right thigh. She has a childhood history of a third-degree scald burn to the same area that did not require skin grafting. The growth was completely removed 2 years ago. On physical examination there is a 5 cm × 2 cm, raised, irregularly shaped purple lesion with a smooth top. Which of the following is the most likely diagnosis?
Angiosarcoma
Malignant melanoma
Squamous cell carcinoma
Kaposi sarcoma
Keloid
41) A mother notices an abdominal mass in her 3-year-old son while giving him a bath. There is no history of any symptoms, but the boy’s blood pressure is elevated at 105/85 mm Hg. Metastatic workup is negative and the patient is explored. The mass shown here is found within the left kidney. Genetic testing reveals deletion of 2 genes on chromosome band 11p13. Which of the following anomalies in addition to the identified tumor is associated with these chromosomal deletions?
Cardiac anomalies
Hemihypertrophy
Hypoglycemia
Macroglossia
Aniridia
42) A 61-year-old man with severe three-vessel coronary disease and diabetes mellitus is scheduled for abdominal surgery. The patient has a long history of coronary disease and had a q-wave myocardial infarction 2 years ago. He has had type 1 diabetes mellitus for 12 years. His medications include atenolol, insulin, and captopril. His last hemoglobin Alc, 3 months ago, was 9.2%. Which of the following is the most predictive of a perioperative complication in this patient?
Poor exercise tolerance
Premature ventricular contractions (PVCs) on ECG
Recent myocardial infarction (MI)
Recent shortness of breath
Use of a beta blocker in the preoperative period
43) A 30-year-old man with a history of Crohn disease develops an enterocutaneous fistula and is placed on total parenteral nutrition through a right subclavian central venous catheter. After 5 days, the patient develops a fever and leukocytosis; CT scan of the abdomen reveals no intra-abdominal abscess. The subclavian catheter insertion site is inspected and noted to be erythematous and painful. Blood cultures are positive. Which of the following organisms is the most likely cause of his fever?
Coagulase-positive staphylococci
Coagulase-negative staphylococci
Group A Streptococcus
Enterococcus
Escherichia coli
44) A 32-year-old woman has an episode of upper gastrointestinal bleeding after a night of heavy alcoholic intake followed by ingestion of multiple aspirin tablets for the hangover. There was no prior vomiting until the time when she felt nauseated, went to the bathroom, and "filled the wash basin with vomiting of bright red bloody fluid." When she arrives in the emergency department, an upper gastrointestinal endoscopy is promptly performed, which confirms a diagnosis of acute erosive gastritis. She has no duodenal ulcer and no esophageal varices. Gastric lavage with ice-cold saline is performed and the bleeding stops. Laser photocoagulation or electrocautery are not used, neither is pitressin infused. She remains hemodynamically stable throughout the procedure, and she has normal hemoglobin. She is sent home 2 hours later. Four hours after discharge, she returns complaining of severe, constant chest pain. She is in acute distress, has a temperature of 39.0C (102.2F), is having chills, and looks quite ill. Physical examination is remarkable for the presence of crepitation to palpation in the upper chest and lower neck, and chest x-rays confirm the presence of air in the mediastinum and the subcutaneous tissues. Which of the following is the most likely diagnosis?
Boerhaave syndrome
dissecting thoracic aortic aneurysm
Gastric perforation
iatrogenic esophageal perforation
Myocardial infarction
45) A 71-year-old man is involved in a minor automobile accident on the road between Guadalajara and Lake Chapala in Mexico. The man is an American citizen who at the age of 65 years retired to a lakeside home in that area. Although he is asymptomatic, he decides to return to the United States to be "thoroughly checked." He is admitted to a veteran's hospital in south Texas, where he undergoes a CT scan of his abdomen. There are no signs of traumatic injuries, but the scan reveals the presence of four simple, thin walled cystic structures, approximately 1 cm in diameter, scattered throughout both lobes of his liver. They have no septations. There are no cysts in the kidneys or pancreas. The man is completely asymptomatic and afebrile. Liver function tests are normal, as is his white blood count and differential. Which of the following is the most likely diagnosis?
Amebic abscesses
Cystadenocarcinoma of the liver
Hydatid cysts
Polycystic liver disease
Simple liver cysts
46) A 78-year-old man comes to the physician because of a bloody urethral discharge for 3 days. He has had increasing frequency of urination and hesitancy for the past 2 years, but these symptoms have never been severe enough to require medical attention. Digital rectal examination reveals a slightly enlarged and firm prostate. Expressed prostatic secretions are negative for bacteria and leukocytes. Collection of clean-catch urine in separate aliquots reveals initial hematuria, with blood present in the first 5 mL. Which of the following is the most likely diagnosis?
Gonococcal infection
Nonbacterial prostatitis
Prostatic carcinoma
Testicular cancer
Urethral carcinoma
47) A 19-year-old man sustains severe lower-extremity trauma, including a femur fracture and a crush injury to his foot. He requires vascular reconstruction of the popliteal artery. On the day after surgery, he becomes dyspneic and hypoxemic and requires intubation and mechanical ventilation. Which of the following is the most likely etiology of his decompensation?
Aspiration
Atelectasis
Fat embolism syndrome
Fluid overload
Pneumonia
48) An 18-year-old gang member is stabbed in the back, just to the right of the midline. Physical examination shows paralysis and loss of proprioception distal to the injury on the right side, and loss of pain perception distal to the injury on the left side. Which of the following is the most likely diagnosis?
Anterior cord syndrome
Central cord syndrome
Complete transection of the spinal cord
Hemisection of the spinal cord
Posterior cord syndrome
49) A 14-year-old girl has a firm, movable, rubbery mass in her left breast. The mass was first noticed 6 months ago and has since grown to about 6 cm in diameter. Which of the following is the most likely diagnosis?
Cancer of the breast
Cystosarcoma phyllodes
Fibrocystic disease (mammary dysplasia)
Giant juvenile fibroadenoma
Intraductal papilloma
50) A 3-week-old infant is brought in because of 2 days of protracted bilious vomiting. He looks acutely ill, and plain x-rays show two large air fluid levels in the upper abdomen, the larger one on the left side and a smaller one on the right side. The radiologist describes the finding as a "double bubble sign." He also reports that there is intraluminal gas distal to those two air fluid levels, but that it is sparse and does not outline distended loops. Which of the following is the most likely tentative clinical diagnosis?
Hypertrophic pyloric stenosis
Intestinal atresia
Malrotation
Meconium ileus
Necrotizing enterocolitis
51) A 16-year-old boy is persuaded by his older brother to accompany him and his friends on a beer-drinking binge. This is the first such experience for the boy, and it leads to the development of severe colicky left flank pain. When rescued by his parents, he is diaphoretic and doubled up in pain. He relates that he began to urinate frequently and profusely after the third or fourth beer and that the pain seized him shortly thereafter. He is tender to fist percussion over the left costovertebral angle but is afebrile. Which of the following is the most likely diagnosis?
Bladder calculi
Low implantation of one ureter
Ureteral stone
Ureteropelvic junction obstruction
Vesicoureteral reflux
52) A 53-year-old man is brought to the emergency department by his wife because of headache and visual changes. Approximately 3 hours ago, he had the acute onset of an extremely severe posterior headache that was non-radiating but was associated with nausea and vomiting. This headache subsided, but over the past hour he has developed mild neck stiffness and pain on flexion of his neck. The patient is not cooperative, so no additional history is known; however, his wife states that he was feeling well until recently and has no allergies. The patient appears moderately uncomfortable and is complaining of the worst headache he has ever experienced. Which of the following is the most likely cause for his symptoms?
Arteriovenous malformation
Cerebellar bleed
Putamenal bleed
Ruptured berry aneurysm
Thalamic bleed
53) A 72-year-old man has a 4-cm hard mass in the left supraclavicular area. The mass is movable and nontender and has been present and steadily growing for the past 3 months. On direct questioning the only additional findings include a 20-pound weight loss and a vague feeling of epigastric discomfort over the past 2 months. Physical examination shows evidence of the weight loss but no other significant findings in the abdominal examination. The supraclavicular mass are obvious, but no other masses can be felt anywhere else in the neck, axillas, or groins. There is occult blood in the stool, and his hemoglobin is 10.5 g/dL. Which of the following would a biopsy of the supraclavicular mass most likely reveal?
Chronic inflammation
Lymphoma
Metastatic gastric cancer
Metastatic squamous cell carcinoma
Metastatic thyroid cancer
54) A 6-year-old boy has insidious development of limping with decreased motion in one hip. He complains occasionally of knee pain on that side. He walks into the office with an antalgic gait. Examination of the knee is normal, but passive motion of the hip is guarded. The child is afebrile, and the parents indicate that his gait and level of activity were completely normal all his life until this recent problem. He has not had a recent febrile illness. Which of the following is the most likely diagnosis?
Avascular necrosis of the capital femoral epiphysis
Developmental dysplasia of the hip
Hematogenous osteomyelitis of the femoral head
Septic hip
Slipped capital femoral epiphysis
55) A patient involved in a car accident sustains burst fractures of several thoracic vertebral bodies. At the time of admission, he has no neurologic function at all below the level of the injury and he has flaccid sphincters. After a few days, there is partial recovery of function; the remaining deficits are loss of motor function and loss of pain and temperature sensation on both sides distal to the injury, with preservation of vibratory and positional senses. Which of the following is the most likely diagnosis?
Anterior cord syndrome
Central cord syndrome
Complete cord transection
Cord hemisection
Spinal shock
56) A 51-year-old man is undergoing abdominal surgery and becomes hypotensive while under general anesthesia. The patient had been doing well during most of the procedure but now has a blood pressure of 80/40 mm Hg. His past medical history is significant for coronary artery disease and diabetes mellitus. A pulmonary artery catheter placed prior to the procedure gives the following data: Central venous pressure 10 mmHg, Pulmonary artery pressure 60/30 mmHg, Pulmonary capillary occlusion 24 mm Hgpressure Cardiac output 2.3 L/min. Which of the following is the most likely diagnosis?
Acute left heart failure
Acute mitral regurgitation
Acute right heart failure
Hypoxic pulmonary vasoconstriction
Sepsis syndrome
57) A 62-year-old man complains of perineal discomfort and reports that there are streaks of fecal soiling in his underwear. Four months ago, he had a perirectal abscess drained surgically. Physical examination shows a perineal opening in the skin lateral to the anus, and a cord-like tract can be palpated going from the opening toward the inside of the anal canal. Brownish purulent discharge can be expressed from the tract. Which of the following is the most likely diagnosis?
Anal fissure
Anorectal carcinoma
Fistula-in-ano
Pilonidal cyst
Thrombosed hemorrhoids
58) A 50-year-old woman with a history of essential hypertension presents to the emergency department with sudden onset of a severe headache, nausea and vomiting, and photophobia. On examination, her BP is 160/100 mmHg. She is mildly confused and has nuchal rigidity, without focal neurologic signs. Which of the following is the most likely diagnosis?
Meningitis
ruptured cerebral aneurysm
Hemorrhagic stroke
Ischemic cerebrovascular accident
transient ischemic attack
59) A 72-year-old man of Norwegian ancestry has a contracted hand that can no longer be extended and placed flat on a table. The problem developed gradually, over many years. He complains of no pain or neurologic abnormalities and, to the extent that the deformity allows, can move his fingers at will. Physical examination demonstrates the deformity described and in addition shows the presence of palpable fascial nodules. Which of the following is the most likely diagnosis?
Carpal tunnel syndrome
De Quervain tenosynovitis
Dupuytren contracture
Palmar tenosynovitis
Rheumatoid arthritis
60) A previously healthy 28-year-old woman develops significant postpartum hemorrhage, with a rapid drop in hematocrit to 18%. Despite aggressive IV fluid resuscitation, the patient has a persistent tachycardia, labile systolic blood pressure, and poor urine output. Ongoing resuscitation includes emergency transfusion with 2 units of O-negative packed red blood cells. During transfusion of the second unit, the patient develops chills, fever, vomiting, and hypertension. These symptoms are most likely the result of which of the following?
a febrile nonhemolytic transfusion reaction
An anaphylactic transfusion reaction
BO incompatibility with acute hemolytic transfusion reaction
A . Delayed hemolytic transfusion reaction
acute bacterial infection transmitted in the blood product
61) A 45-year-old woman underwent elective surgery for an inguinal hernia. In the postoperative recovery room, she developed nausea, vomiting, and acute abdominal pain. She has a history of systemic lupus erythematosus, pernicious anemia, type 1 diabetes, chronic low back pain, and uterine fibroids. Her preoperative medications include monthly vitamin B-12 injections, insulin, prednisone, hydroxychloroquine, and acetaminophen. Her blood pressure is 70/40 mm Hg and heart rate is 110/min. Initial laboratory studies show blood glucose of 50 mg/dl. Which of the following is the most likely cause of her condition? . Postoperative bleeding . Diabetic ketoacidosis . Intra-abdominal abscess
Postoperative bleeding
Diabetic ketoacidosis
Intra-abdominal abscess
Intestinal obstruction
Adrenal insufficiency
62) A 45-year-old woman, who wears high-heeled, pointed shoes, complains of pain in the forefoot after prolonged standing or walking. Occasionally, she also experiences numbness, a burning sensation, and tingling in the area. Physical examination shows no obvious deformities and a very tender spot in the third interspace, between the third and fourth toes. There is no redness, limitation of motion, or signs of inflammation. Which of the following is the most likely diagnosis?
Gout
Hallux rigidus
Metatarsophalangeal articulation pain
Morton's neuroma
Plantar fasciitis
P1956 Q63
6 |
3) A 45-year-old man presents to the physician’s office for evaluation of a skin lesion on his abdomen. He states that the lesion has been present for 1 year, but has recently enlarged over the last 2 months. The mass is nontender, and he is otherwise asymptomatic. Past history is unremarkable. Examination reveals a 3-cm, pigmented, irregular skin lesion located in the left lower quadrant of the abdomen, as shown in Figure 6-12. Heart, lung, and abdominal examination are normal. There are no palpable cervical, axillary, or inguinal lymph nodes. Chest x-ray and liver fun |
Squamous cell carcinoma
Basal cell carcinoma
Merkel cell carcinoma
Melanoma
Keratoacanthoma
64) A 58-year-old man presents with pain in the left leg after walking more than one block that is relieved with rest. On physical examination, distal pulses are not palpable in the left foot and there is dry gangrene on the tip of his left fifth toe. An ankle-brachial index on the same side is 0.5. Which of the patient’s symptoms or signs of arterial insufficiency qualifies him for reconstructive arterial surgery of the left lower extremity?
Ankle-brachial index less than 0.7
Rest pain
Claudication
Absent palpable pulses
Toe gangrene
65) An 84-year-old man is brought to the emergency department because of 1 hour of severe back pain. He also had syncope that lasted <1 minute. Before arriving at the hospital, he had an episode of gross hematuria, which he has never had before. He also complains of some shortness of breath. He denies chest pain, cough, nausea, vomiting, headache, and neck pain. His blood pressure is 72/55 mm Hg and pulse is 112/min and regular. His pulse oximetry shows 92% on room air. His ECG shows sinus tachycardia with prominent horizontal ST segment depression in the anterior chest leads. Which of the following is the most likely diagnosis?
Abdominal aortic aneurysm rupture
Acute mesenteric ischemia
Acute myocardial infarction
Massive pulmonary embolism
Nephrolithiasis with renal colic
66) A 54-year-old man comes to the physician because of edema of his right ankle. He reports heaviness and cramping in the same leg that is worse after a long day at work. The swelling is usually reduced significantly when he wakes up in the morning and worsens progressively throughout the day. He denies any other symptoms. He has no significant medical problems except hypertension, for which he takes atenolol. His temperature is 36.7° C (98° F), blood pressure is 120/76 mm Hg, pulse is 80/min and respirations are 16/min. JVP is normaL Lungs are clear to auscultation. There are no murmurs. There is no hepatosplenomegaly. Examination shows edema of the right ankle. Doppler examination of the leg shows no evidence of thrombosis. Which of the following is the most likely cause of his edema?
Lymphatic obstruction
Impaired cardiac contraction
Reduced diastolic filling of the heart
Increased urinary loss of protein
Venous valve incompetence
67) A 68-year-old man presents to the physician’s office complaining of progressive dysphagia over the last 3 months associated with mild chest discomfort. He reports a 15-lb weight loss, a 30 pack-year smoking history, and occasional alcohol intake. The physical examination, including vital signs, is unremarkable. A chest x-ray was normal, and a barium esophagogram shows an irregular filling defect in the distal third of the esophagus with distortion and narrowing of the lumen. Which of the following is the most likely diagnosis?
Esophagitis with stricture
Esophageal carcinoma
Lung carcinoma with invasion into the esophagus
lymphoma
Achalasia
68) A 29-year-old man presents with a 2-day history of severe left-sided scrotal pain and swelling. He is sexually active and has had "many" sexual partners. His temperature is 38.2 C (100.8 F), blood pressure is 120/70 mm Hg, and pulse is 80/min. Examination shows unilateral intrascrotal tenderness and swelling. Testicular support makes the pain less intense. Which of the following is the most likely diagnosis?
Epididymitis
Prostatitis
Testicular torsion
Urethritis
Varicocele
69) A 65-year-old woman presents to the physician’s office for her yearly physical examination. She has no complaints except for a recent 10-lb weight loss. Past history is pertinent for a 40 pack-year smoking history, hypertension, asthma, and hypothyroidism. Examination reveals a thin woman with normal vital signs and unremarkable heart and abdominal examinations. Lung examination reveals mild wheezing and a few bibasilar rales. A chest x-ray is obtained and is shown in Figure 6-13. A chest x-ray obtained 3 years ago was normal. Yearly laboratory tests including a CBC, electrolytes, and lipid panels are normal. Which of the following is the most likely diagnosis?
Small cell lung cancer
Tuberculosis
Nonsmall cell lung cancer
hamartoma
abscess
70) A 24-year-old man comes to the physician because of 1 week of abdominal pain. It is localized in the right lower quadrant and somewhat exacerbated by motion. Over the past 2 days, it has radiated to the back. He initially had two episodes of vomiting but now just has decreased appetite. He had one episode of diarrhea 1 day ago. He denies urinary frequency. His other medical problems include mild intermittent asthma and gastroesophageal reflux disease. He traveled to Mexico for 5 days 1 month ago and did not have any gastrointestinal symptoms during his stay there. His mother was diagnosed with colon cancer at the age of 49 years. His temperature is 38.2°C (100.8°F), blood pressure is 122/77 mm Hg, and pulse is 109/min and regular. Physical examination reveals prominent tenderness in the right lower quadrant, without rebound. Flexion of the right hip against resistance elicits significant abdominal pain. Laboratory results show:WBC count 16,000/mmHemoglobin 14.2 g/dlPlatelet count 620,000/mmPotassium 4.5 mEq/LCreatinine 1.0 mg/dlWhich of the following is the most likely diagnosis?
Appendiceal perforation
Colonic malignancy
Complicated pyelonephritis
Inflammatory bowel disease
Parasitic colitis
71) A 35-year-old woman is involved in a motor vehicle crash, sustaining a severe pelvic fracture, with disruption of the pelvic ring. In the trauma resuscitation room, she is confused and tachypneic, with a blood pressure of 90 mmHg systolic and a heart rate of 130/min. Laboratory investigations include serum electrolyte analysis, revealing a sodium of 139, a chloride of 103, and a bicarbonate of 14 meq/L. This patient demonstrates which of the following?
nonanion gap metabolic acidosis
Anion gap metabolic acidosis
Metabolic alkalosis
Respiratory acidosis
Normal serum electrolytes
72) A 1-day-old infant with Down syndrome, feeding intolerance, bilious vomiting, and a double bubble on plain radiographs (Figure 6-18). Which one is the most likely diagnostic?
Congenital hypertrophic pyloric stenosis
Annular pancreas
Duodenal atresia
Midgut volvulus
intussusception
73) A 43-year-old man develops excruciating abdominal pain at 8:23 PM (he looked at his watch when the pain "hit him"). When seen in the emergency department about 30 minutes later, he has a rigid abdomen, lies motionless on the examination table, has no bowel sounds, and is obviously in great pain, which he describes as constant and encompassing the entire abdomen. There is very severe pain when deep palpation of the abdomen is attempted in any of the four quadrants. However, the examining hand cannot make much of an indentation because of the impressive muscle guarding. When the attempt is aborted, he manifests severe rebound tenderness. X-ray films show free air under both diaphragms. Which of the following does this man most likely have?
Acute abdomen, the nature of which cannot yet be defined
Acute inflammatory process affecting an intra-abdominal viscera
Acute obstruction of an intra-abdominal viscera
Ischemic process affecting intra-abdominal organs
Perforation of the gastrointestinal tract
74) A 56-year-old woman presents for evaluation of a murmur suggestive of mitral stenosis and is noted on echocardiography to have a lesion attached to the fossa ovalis of the left atrial septum. The mass is causing obstruction of the mitral valve. Which of the following is the most likely diagnosis?
Endocarditis
Lymphoma
Cardiac sarcoma
Cardiac myxoma
Metastatic cancer to the heart
75) A 54-year-old man presents to the emergency department on transfer from another hospital at the request of the family. He was admitted to the outside hospital 2 weeks ago with abdominal pain, nausea, vomiting, and fever. He was treated with antibiotics, NG tube decompression, and TPN without significant improvement. He developed jaundice 2 days ago. His past history is pertinent for a 40 pack-year smoking history, chronic alcohol abuse, and diabetes. Examination reveals a mildly jaundiced patient with vital signs of temperature 100°F, pulse rate 95/min, and BP 110/60 mmHg. Cardiac examination is unremarkable, lung examination reveals decreased breath sounds at the bases bilaterally, and abdominal examination reveals fullness in the epigastrium with tenderness and voluntary guarding. Which one is the most likely diagnosis?
hepatitis A
Hemolysis
Pancreatitis
Liver metastases
Cirrhosis
76) A 65-year-old male cigarette smoker reports onset of claudication of his right lower extremity approximately 3 weeks previously. He can walk 3 blocks before the onset of claudication. Physical examination reveals palpable pulses in the entire left lower extremity, but no pulses are palpable below the right groin level. Non-invasive flow studies are obtained and are pictured here. What is the level of the occlusive process in this patient? |
P1962 Q76
|
Right anterior tibial artery
Right superficial femoral artery
Right profunda femoris artery
Right external iliac artery
Right internal iliac artery
77) A 5-week-old infant presents with a 1-week history of progressive nonbilious emesis, associated with a 24-hour history of decreased urine output. The infant continues to be active and eager to feed. On examination, the infant has a sunken fontanelle and decreased skin turgor. The abdomen is scaphoid, and with a test feed, there is a visible peristaltic wave in the epigastrium. Which of the following is the most likely diagnosis?
Viral gastroenteritis
gastroesophageal reflux
Urinary tract sepsis
Pyloric stenosis
Milk protein allergy
78) A 5-week-old infant presents with a 1-week history of progressive nonbilious emesis, associated with a 24-hour history of decreased urine output. The infant continues to be active and eager to feed. On examination, the infant has a sunken fontanels and decreased skin turgor. The abdomen is scaphoid, and with a test feed, there is a visible peristaltic wave in the epigastrium. The diagnosis is best confirmed by which of the following?
abdominal ultrasound
Careful clinical examination with palpation of an epigastric mass
UGI contrast study
Surgical exploration
endoscopy
79) An 80-year-old man is found to have an asymptomatic pulsatile abdominal mass. An arteriogram is obtained (shown below). Which of the following is the most frequent and lethal complication of this condition? |
P1963 Q79
|
Rupture
Acute thromboembolism
Dissection
High-output congestive heart failure
Myocardial infarction
80) An older, overweight man complains of disabling, sharp heel pain every time his foot strikes the ground. The pain is worse in the mornings, preventing him from putting any weight on the heel. X-ray films show a bony spur matching the location of his pain, and physical examination shows exquisite tenderness to direct palpation right over that heel spur. Furthermore, when the ankle is dorsiflexed, the entire inner border of the fascia is tender to palpation. Which of the following is the most likely diagnosis?
Epiphysitis of the calcaneus
Fracture of the posterolateral talar tubercle
Plantar fasciitis
Posterior Achilles tendon bursitis
Posterior tibial nerve neuralgia
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