C2 proteins

A detailed illustration of immunoglobulin structures with lab equipment in the background, vibrant colors, educational infographic style

C2 Proteins Knowledge Quiz

Test your knowledge on the complexities of C2 proteins and related immunology topics with this comprehensive quiz! Designed for medical students, healthcare professionals, and anyone interested in the subject matter, this quiz features 18 thought-provoking questions.

Highlights of the quiz:

Covers key concepts in immunoglobulins and plasma proteins
Multiple choice format for engaging learning
Ideal for enhancing your understanding in clinical biochemistry and laboratory medicine

18 Questions4 MinutesCreated by ExploringScience345

The diagnosis of myeloma requires that two of the following are present

Organ damage, high level of uric acid, paraprotein in urine

Paraprotein in urine, anemia, low platelet count

Paraprotein in serum/urine, bone marrow infiltration with plasma cells, organ damage

Hypercalcemia, paraprotein in serum, pancytopenia

Paraprotein in serum, paraprotein in urine, organ damage

Indicate the wrong statement regarding the immunoglobulins

Polyclonak hyperimmunoglobulinemia (hypergammaglobulinemia) results in a diffuse increase in protein mass around the gamma globulin region on electrophoresis

Polyclonal hyperimmunoglobulinemia (hypergammaglobulinemia) results from an increased synthesis from a number of cell (lymphocyte) lines

All myelomas produce heavy chains

Paraproteins may be found in patients without any associated pathology

Paraproteins may arise from any if the immunoglobulin class

Indicate the wrong statement regarding the plasma proteins

Hypoalbuminemia can be induced by hypervolemia (or over hydration)

Increase in total protein in a serum sample is usually due to an increase in the globulin fraction

Decrease in total protein in a serum sample is usually due to hypoalbuminemia

Hypoalbuminemia occurs in advanced liver disease

Hypoealbuminemia in the inflammatory response is due to decreased albumin synthesis

Which of the following are known to decrease in response to injury

Properdin, haptoglobin, C3 complement, a1-antitrypsin, selenium

T3, selenium, albumin, iron, HDL

Haptoglobin, C5 complement, HDL, LDL, ceruloplasmin, TSH

Haptoglobin, C4 and C5 complement, a1-antitrypsin, ceruloplasmin, fibrinogen

Haptoglobin, C3 complement, HDL, a2-macroglobulin, serum amyloid-A

Indicate the wrong statement regarding the immunoglobulins

Paraproteins are found in heavy chain disease

In 50% of cases of multiple myeloma only light chains are found

Light chains in urine are referred to as Bence-Jones proteinuria

Paraproteins may be found on electrophoresis

Paraproteins are found in multiple myeloma

All of the following acute phase proteins are known to increase in response to injury except

Indicate the wrong statement regarding the metabolic response to injury

Ebb phase may progress to the recovery

ESR is useful in monitoring day-to-day changes in the inflammatory response

Albumin is useful in monitoring day-to-day changes in the inflammatory response

Ebb phase may progress to the SIRS

Flow phase may last for weeks

Indicate the wrong statement regarding the immunoglobulins/paraproteins

Paraprotein is an intact immunoglobulin (or its fragment)

Benign paraproteinemia refers to the presence of plasma fibrinogen in the gamma region on electrophoresis

Paraproteins are found in Waldenstrøms macroglobulinemia

Paraprotein (monoclonal hypergammaglobulinemia) and polyclonal hypergammaglobulinemia can be distinguished by gel electrophoresis

Urine electrophoresis can show the presence of Bence-Jones protein

Common biochemical derangements in SIRS include

Hypernatremia, hypoalbuminemia, high T3

SIAD, hypoalbuminemia, high T3

SIAD, hypoalbuminemia, low T3

Hypernatremia, hypoalbuminemia, high TSH

SIAD, low iron, high TSH

Criteria for the diagnosis of SIRS include

Temp > 38, pCO2 <32mmHg, WBC > 12000 per mm3, heart rate >100/min, respiratory rate >20/min

Temp >37, pCO2 >32mmHg, WBC > 4000 per mm3, heart rate >100/min, respiratory rate >12/min

Temp > 38, pCO2 >32mmHg, WBC > 4000 per mm3, heart rate >90/min, respiratory rate >20/min

Temp > 38, pCO2 <32mmHg, WBC > 12000 per mm3, heart rate >90/min, respiratory rate >20/min

Temp > 38, pCO2 >32mmHg, WBC > 12000 per mm3, heart rate >100/min, respiratory rate >12/min

Which of the following are known to increase in response to injury

Haptoglobin, C5 complement, HDL, LDL, ceruloplasmin, TSH

Properdin, haptoglobin, C3 complement, a1-antitrypsin, selenium

Haptoglobin, C3 complement, HDL, a2-macroglobulin, serum-amyloid-A

T2, selenium, C4 complement, fibrinogen, C-reactive protein, a2-macroglobulin

Haptoglobin, C4 and C5 complement, a1-antitrypsin, ceruloplasmin fibrinogen

Indicate the wrong statement regarding the CRP and ESR

The rate of change of ESR is less than that of CRP

CRP reflects an intensity of the acute phase response

In the evaluation of paraproteinemias CRP is more useful than ESR

ESR reflects an intensity of the acute phase response

ESR can be affected by anemia

C2 proteins

C2 Proteins Knowledge Quiz

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