BIOCHEM FINAL
Biochemistry Final Exam Quiz
Test your knowledge of glycolysis and enzymatic processes with our comprehensive Biochemistry Final Exam Quiz! This quiz is designed to challenge your understanding of key biochemical pathways and the fun
- Multiple choice questions
- Covers essential topics in biochemistry
- Ideal for students preparing for final exams
Glycolysis cannot occur under anaerobic conditions
True
False
The enzyme hexokinase catalyzes
Glucose phosphorylation to glucose-6-phosphate
ATP production
Conversion of glucose to fructose-6p
Which of the following is a structural component of insects (such as cockroach) exoskeleton?
Amylose
Cellulose
Chitin
Starch
Which of the following is a highly branched polymer of glucose?
Amylose
Cellulose
Chitin
Glycogen
Which of the following reactions requires NADH?
Conversion of Phosphoenol pyruvate into Pryruvate
Conversion of Pyruvate into lactic acid
Conversion of Fructose-6-phosphate into Fructose-1,6-bisphosphate
How many ATP molecules are produced (net production) when 4 molecules of glucose are metabolized through glycolysis?
2
4
6
8
The enzyme phosphofructokinase catalyzes
Fructose-6-phosphate phosphorylation
Glucose phosphorylation to glucose-6-phosphate
Glucose-6-phosphate isomerization
The reaction catalyzed by Pyruvate kinase yields
ATP and Pyruvate
Lactate
AMP
The enzyme Glucokinase has a Km value higher than Hexokinase
True
False
The formation of lactic acid is part of glycolysis pathway
True
False
The enzyme Glucokinase has a Km value lower than Hexokinase
True
False
Which 3-carbon molecule is one of the final products of glycolysis?
Pyruvate
Phosphoenolpyruvate
Phosphoglycerate
Fructose
How many ATP molecules are produced (net production) when 2 molecules of glucose are metabolized through glycolysis?
4
16
1
8
The reaction catalyzed by phosphoglycerate kinase yields
ATP and 3-Bisphosphoglycerate
ADP and G6P
Fructose and ATP
Which of the following is inhibited by Citrate
Phosphofructokinase
Pyruvate Kinase
Hexokinase
Fructose 1,6-bisphosphate is cleaved into D-glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. The enzyme involved in this reaction is
Aldose
Enolase
Triose phosphate isomerase
Triose Kinase
The conversion of pyruvate to lactic acid allows
The regeneration of NAD+
The regeneration of NADH
The enzyme Glucokinase catalyzes
Fructose phosphorylation to fructose-6-phosphate
Glucose phosphorylation to glucose-6-phosphate
ATP Production
The production of lactic acid from pyruvate allows the recycling of ____ which is needed for glycolysis
NADH from NAD+
NAD+ from NADH
How many oxygen molecules are utilized during glycolysis per 2 molecules of glucose
2
6
0
4
The enzyme phosphofructokinase is alloserically activated by
Fructose 2,6- bisphosphate (F2,6BP)
ATP
Fructose 1,6-bisphosphate (F1,6BP)
When the levels of ATP are reduced due to high utilization
[AMP] is increased
[AMP] is decreased
The enzyme pyruvate kinase is inhibited by
ATP
Fructose 1,6 phosphate
AMP and fructose 2,6-bisphosphate
The enzyme Hexokinase is inhibited by
ATP
AMP and fructose 2,6-bisphosphate
Fructose 1,6 phosphate
Glucose 6 phosphate
The synthesis of the enzyme glucokinase is induced by
Fructose
Insulin
Fructose
Glucose 6 phosphate
A kinase is an enzyme that
removes phosphate groups of substrates
Uses ATP to add a phosphate group to the substrate
The electron donor to cytochrome C
Coenzyme Q (ubiquinol)
NADPH
Uncoupling proteins (UCP) enhance the production of ATP in mitochondria:
True
False
Which of the following does not occur in the mitochondria
Beta Oxidation
Kreb Cycle
Glycolysis
Fatty acid synthesis
A & B
C & D
For each molecules of glucose, how many CO2 are produced in the mitochondria
2
4
6
8
Pyruvate dehydrogenase produces
Acetyl-Coa, C02 and NADH
Citrate and FADH
Pyruvate and FADH2
The enzyme Pyruvate dehydrogenase is inhibited by
NAD
Acetyl-CoA
Pyruvate
Before pyruvate enters the citric acid cycle it needs to be converted into
Lactic Acid
Acetyl- CoA
Citric acid
Which hormone promotes Glycogenolysis
Insulin
Glucagon
CAMP binds and inactivates
PKA
Glycogen synthase
PKA is more active when
Glucagon levels in Blood are high
Insulin levels in blood are high
High levels of blood glucose
Slowdown Pyruvate dehydrogenase
Speed up Pyruvate Dehydrogenase
High levels of NADH and ATP in mitochondria
Slowdown Pyruvate dehydrogenase
Speed up Pyruvate Dehydrogenase
Which can generate more ATP through the electron transport chain?
NADH
FADH2
The final electron acceptor in the electron transport chain is
H2O
Oxygen
Coenzyme Q
NAD+
Glycogen phosphorylase is more active when
Phosphorylated
Nonphosphorylated
PKA is more active during
Fasting
Fed state
PP1 is more active during
Fasting
Fed state
PP1 is more active when
Glucagon levels in the blood are high
Insulin levels in the blood are high
Lack of insulin in patients leads to
Lack of glycogen synthesis
Hyperglycemia
Inactivation of PP1
Activation of PP1
A,B,D
A,B,C
Muscle lacks of
Hexokinase
Glucose-6-phosphate
Glycogenolysis in muscle causes release of glucose to blood
True
False
Coenzyme NAD+ is synthesized from
Thiamin
Riboflivin
Niacin
Coenzyme FAD is synthesized from
Thiamin
Riboflavin
Niacin
Coenzyme TPP is synthesized from
Niacin
Thiamin
Riboflavin
Coenzyme TPP is important for the activity of
Pyruvate dehydrogenase
Malate dehydrogenase
Citrate synthase
How many electrons can carry coenzyme Q
1
2
3
How many cycles of the Krebs Cycle are needed to completely metabolize 1 molecule of glucose?
1
2
3
Which molecule(s) can cross mitochondria membrane?
Malate
Pyruvate
Both
At the respiratory chain, 1 FAD produces
1.5 ATP
2.5 ATP
4 ATP
NADH inhibits
Citrate synthase
Pyruvate dehydrogenase
Cytochrome C reductase
Malate dehydrogenase
In glycogen, the linear chains are formed by ____ glycosidic linkages while the branches are formed by ____ glycosidic linkages.
Alpha-1,6/alpha-1,4
Alpha-1,4/alpha-1,6
Adenylate cyclase catalyzes the conversion of
ATP into cAMP
ATP into ADP
ATP into AMP
Gluconeogenesis is more active during
Fasting
Fed State
The enzyme fructose-1,6-bisphosphatase. Is part of which pathway?
Glycolysis
Gluconeogenesis
Pentose phosphate
During long term fasting (more than 24h), glucose is produced in the liver from
Glycogen
Gluconeogenesis
Gluconeogenesis is the pathway that produces
Glucose from pyruvate
Pyruvate from glucose
During Beta oxidation there is production of
NADH
FADH2
Acetyl CoA
All the above
A,B,C
Gluconeogenesis is the process of
Production of glucose from fatty acids
Production of glucose from glycogen
Production of glucose from pyruvate and some acid
Gluconeogenesis is a complete reversal of "all the enzymes of glycolysis"
True
False
Fructose 1,6 bisphosphatase is activated by
AMP
Citrate
F2,6BP
Phosphoenolpyruvate Carboy Kinase is inhibited by
ATP
ADP
Citrate
Gluconeogenesis is more active (in general)
When the levels of glucose are high and ATP is low
When the levels of glucose are low and ATP is high
Acetyl-CoA carboxylase is more active when
Non-phosphorylated
Phosphorylated
Ketogenesis is increased during
Long term fasting
Short term fasting
Ketone Bodies are produced in the
Muscle
Liver
Beta oxidation of odd numbered fatty acids requires which vitamin
Thiamin
Biotin
B6
How many acetyl CoA are produced by beta -oxidation from a fatty acid with 17 carbons
9
8
7
Thiokinase catalyzes
Synthesis of acyl- CoA
Synthesis of acyl carnitine
Enzyme CoA transferase is present in
Muscle
Liver
What is the limiting/ regulatory step for beta oxidation
Thiokinase reaction
Entry into Mitochondria
Regulatory step for fatty acid synthesis is catalyzed by
Acetyl-coA synthase
3-ketoacyl-ACP reductase
Fatty Acid Synthesis occurs in
Mitochondria
Cytosol
The hormone sensitive lipase activity allows the release of
2 fatty acids from triglycerides
3 fatty acids from triglycerides
PKA activates/induces the activity of
Acetyl-CoA carboxylase
Hormone sensitive lipase
Insulin inactivates/inhibits the activity of
Hormone sensitive lipase
Acetyl-CoA carboxylase
Enoyl-ACP reductase
The synthesis of fatty acids requires
NADH
NADPH
Which enzyme regulates cholesterol synthesis
HMG-CoA Synthase
Acetyl-coA synthase
The formation of UREA
Is a catabolic process that generates ATP
Requires ATP
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