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A detailed illustration depicting inflammation and tissue repair processes, including cells like macrophages and neutrophils, damaged tissue, and healing pathways, in a medical or scientific style.

Inflammation and Repair Quiz

Test your knowledge on key concepts related to inflammation, tissue repair, and cellular processes. This quiz features 12 challenging multiple-choice questions designed for students, educators, and anyone interested in understanding the mechanisms behind inflammation.

Covering important topics like chronic inflammation, ischemic cell injury, and pathogenesis.
Designed for those studying medicine, biology, and related fields.

12 Questions3 MinutesCreated by ExaminingCell32

In which of the following diseases does the granulomatous reaction typically produce caseous necrosis?

Chron disease

Foreign body reaction

Mycobacterium tuberculosis infection

Sarcoidosis

The morphologic hallmark of general chronic inflammation is:

Formation of Langhans giant cells

Infiltration with mononucular cells

Infiltration with neutrophils

Presence of caseous necrosis

Which of the following is NOT a step in repair by connective tissue deposition:

Granulation tissue formation

Granuloma formation

Fibrous scar formation

Tissue remodeling

Which of the following is NOT a component of the acute inflammatory response

Dilation of small vessels leading to an increase in blood flow

Emigration of neutrophils and macrophages from the microcirculation into the focus of injury

Increased permeability of the microvasculature

Transformation of activated macrophages to epithelioid cells

The release of damage associated molecular patterns (DAMPs) from injured cells can result in all the following EXCEPT:

Activate cell surface receptors of neighboring cells to trigger the apoptotic cascade

Activate receptors on macrophages and other cell types

Stimulate secretion of cytokines to induce inflammatio

Trigger phagocytosis of cell debris

CRISPR is which of the following?

A brand of cautery instrument

A gene editing system that can repair inherited genetic diseases and insert pathogenic mutations into cancer stem cells

An enzyme cascade that mediates apoptosis in cells exposed to noxious external stimuli

Concise RISk PRotection software tool in the EMR

Glycolipids are preferentially located where in the cell?

In lysosomes

In the cytoplasm

On the extracellular face of the plasma membrane

On the inner face of the plasma membrane

Early loss of selective membrane permeability, leading ultimately to overt membrane damage, can be caused by all the following EXCEPT:

Activation of the apoptotic cascade

Calcium activated phospholipases

Cytoskeletal degradation by calcium activated proteases

Lipid peroxidation due to reactive oxygen species

Which of the following locations in the cell cycle contains a checkpoint that can cause arrest in proliferation if there is DNA damage?

G1 restriction point

G1/S interface

S phase

M phase

The term pathogenesis refers to:

The initiating cause of a disease

The sequence of molecular, biochemical, and cellular events that lead to the development of disease

The structural alterations in cells or tissues that are characteristic of a diseas

Functional abnormalities resulting from genetic, biochemical, and structural changes in cells and tissues

Ischemic cell injury is caused by:

Activation of the complement system

Oxidative stress leading to production of reactive oxygen and nitrogen species

Reduced blood flow, due to arterial obstruction or systemic hypotension

Reduced blood oxygen levels with maintained blood flow due to pulmonary insufficiency

The major constituents of the extracellular basement membrane are:

Type I collagen and elastin

Type II collagen and actin

Type III collagen and fibronectin

Type IV collagen and laminin

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Inflammation and Repair Quiz

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