Quiz on cholesterol and the pathophysiology (ILO7)

What is traditionally called 'bad' cholesterol?

LDL

HDL

What is the physiological function of LDL?

Aids digestion

act as a major transporter of cholesterol

What is the physiological function of HDL?

helps the body absorb iron

take excess cholesterol and return it to the liver for excretion

What below are some functions of cholesterol?

Component of cell membrane

biosynthesis of steroids

biosynthesis of bile acid

aid hepatic recovery

Hypercholesterolaemia is an important risk factor for what pathologies?

coronary heart disease

atherosclerosis

gout

peripheral arterial disease

What are the adverse complications of Hypercholesterolaemia?

Stroke

Depression

Myocardial infarction

Erectile dysfunction

What happens in the vessel wall as LDL builds due to higher circulating levels?

Becomes oxidised and causes inflammation

Becomes phosphorylated

Binds to receptors

Blocks receptors

What is formed as a consequence of inflammation of vessels caused by LDL?

Plaques

Clots

Fibres

Holes

What happens to arteries over time as plaque forms?

They calcify

Stiffen and narrow

They have kinks

They get bigger

As well as plaques, what else does the inflammation promote the growth of?

Neutrophils

Nerves

Fibrous cap

C reactive protein

How does the formation of plaque and the fibrous cap over cause heart attacks?

fibrous cap ruptures, triggers the release of clotting factors

Promotes the synthesis of platelets

Widens the vessels

Causes vessels to be leaky and inflammatory markers to be released

Risk factors for secondary hypercholesterolaemia?

High saturated fat diet

Diabetes

Obesity

Lymphoma

{"name":"Quiz on cholesterol and the pathophysiology (ILO7)", "url":"https://www.quiz-maker.com/QG0AENU","txt":"What is traditionally called 'bad' cholesterol?, What is the physiological function of LDL?, What is the physiological function of HDL?","img":"https://www.quiz-maker.com/3012/images/ogquiz.png"}

Quiz Maker