Antibiotics Lecture
Antibiotics Knowledge Quiz
Test your understanding of antibiotics with this comprehensive quiz designed for students and professionals alike. Dive into critical concepts surrounding Beta Lactams, Vancomycin resistance, and mechanisms of action for various antibiotic classes.
You'll face multiple-choice questions covering:
- Mechanisms of action
- Resistance mechanisms
- Key terms and definitions
Which of the following is a Beta Lactam?
Meropenem
Vancomycin
Amoxicillin
Daptomycin
What critical bacterial function do beta lactams target?
Transpeptidation
Cell Wall Integrity
Transglycolation
Translation
What does the binding of penicillin to Penicillin binding protein cause?
Conversion of GDP to GTP
Phosphorylation of transpeptidase
Acetylation of transpeptidase
Formation of CAMP
Transpeptidase is a bifunctional enzyme. What is its function other than transpeptidation?
Transglycolase
Tyrosine phosphorylation
Transferase
Translation initiation
What is the function of Beta lacatamase
Alteration to Beta lactam binding site
Degradation of beta lactams
Pumps Beta lactams out of the cell
Changes permeability of the bacterial cell
What is the most common form of transmitting beta lactam resistance?
Transformation
Plasmid transfer (conjugation)
Transduction
Transposition
SCCmec, the causative agent of most antibiotic resistance codes for what?
PBP alpha
OriC
PBP2A
RAS
How do Beta lactamase inhibitors allow beta lactams to work?
Binding to beta lactamase
Preventing the degradation of Beta Lactam
Altering PBP
Acetylates Transpeptidase
What generation of cephalosporins is ceftriaxone part of?
1st generation
3rd generation
5th generation
3rd generation with antipseudomonal
What amino acid combination does Vancomycin target
D-glycine L- valine
D-alanine D-alanine
D- serine D-glutamine
D- lysine D- alanine
What prevents the binding of Vancomycin in Vancomycin resistant antibiotics
Glutamic acid
Lactic acid
PBP2
D-alanine D-alanine
Which of the following inhibits protein synthesis via the 30s ribosomal subunit?
Oxazolidinones
Aminoglycosides
Macrolides
Chloramphenicol
What part of the ribosome do tetracyclines bind to?
A site
P site
E site
None, binds to shine delgarno sequence
What is the most common form of tetracycline resistance
Tetracyclinases
Efflux pumps
Proteins binding to tetracycline
Increased pH
Which of the following would not inhibit the action of Aminoglycosides?
Low oxygen
Low pH
High heat
High oxygen levels
Which of the following antibiotics becomes better at killing bacteria the higher the concentration?
Gentamicin
Tetracycline
Clindamycin
Meropenem
What enzyme do sulfonamides inhibit?
Dihydropteroate synthase
Dihydrofolate reductase
Topoisomerase
Tetrahydrofolic acid
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