Allergology test 2021

Which of the following clinical manifestations can occur in IgE mediated food allergy?

Oral allergy syndrome

Allergic proctocolitis

Heiner’s syndrome

Food protein induced enterocollitis syndrome (FPIES)

Egg allergy-choose the true statement.

Most of the allergenic egg proteins are found in the egg white

Ovomucoid has been shown to be the dominant allergen in egg

The most common type of egg allergy is IgE mediated

All statements are correct

. Cow's milk protein (CMP) allergy. Choose the false statements:

Cow's milk is the most common cause of food allergy in children

the severe shock-like reactions with metabolic acidosis are characteristic for „allergic proctocolitis”

In the case of an allergy to cow’s milk protein in infants on milk formula,the infant should be maintained on an elimination diet using a therapeutic formula for least 3 months

Free amino acids formula (AFF) is a first line treatment for most infants with cow's milk protein allergy

Heiner's syndrome is

A. IgE mediated food allergy

Cell -mediated food allergy to milk

Toxic reaction to food

Non immune mediated enzymatic intolerance

When Is the best time to start introducing solid foods into the infant's diet- the so-called immune window?

Between 4-6 months of age

After 6 months of age

It is important to withhold highly allergenic foods such as milk, egg, peanuts, and fish for the first 2 years life

None of them

Who was the creator of the term "hypersensitivity"?

Robert Koch

Emil von Behring

Charles Brichet and paul portier

Maurice arthus

Who first identified the role of IgE antibodies?

Kimishige and Teruko Ishizaka

Bengt Samuelsson

Ralph M. Steinman

Karl landsteiner and Merrill Chase

Dust mites allergy can be a triggering factor of

A. Allergic asthma

Allergic rhinitis

All of the above

Patient with allergic rhinitis , asthma and oral allergy syndrome has itchy mouth and swollen lips after eating a melon. The patient may be allergic to:

Dust mites

Alternaria

Cladosporium

Grass

Choose the common cause of perennial rhinitis

Animal dander

Dermatophagoides pteronyssinus

Mugwort

Animal dander and Dermatophagoides pteronyssinus

What is atopy?

special type of (otherwise harmless) antigens that elicit allergic reactions in sensitized individuals

the genetic propensity to develop an IgE Ab response to common allergens

The response,characterized by local erythema,induration,hemorrhage and necrosis following repeated intradermal injections of protein allergens

Tendency to rough,dry skin

Indicate the symptoms that occur rarely in chronic allergies/all-year allergies

. Indicate the most common manifestation of anaphylaxis?

cutaneous symptoms- eg:urticaria/angioedema

Cardiovascular symptoms eg.syncope

respiratory symptoms

Gastrointestinal symptoms eg.vomiting

Choose the correct statement/s about pollen seasons

The grasses pollinate first

Plants don't release their pollen at the same time every year

In general dry, warm and sunny weather is favorable for high pollen concentration

Most plants (but not all), release their pollen in the evenings

15. Pollen ivy-choose the correct statement/statements

It causes severe allergic reactions in many people

. It causes contact dermatitis

Careful washing of the exposed skin after suspected contact may prevent the reaction

All of the above

Your patient has had a serious anaphylactic reaction to anaphylactic shock.Indicate the appropriate grade of anaphylaxis classification.

grade I

grade II

grade III

grade IV

Anaphylaxis-indicate the correct statements.

Mechanism is widespread activation of mast cells throughout the body

The more rapidly anaphylaxis develops, the more likely the reaction is to be severe and potentially life-threatening

Corticosteroids are first -line therapy in treatment of anaphylaxis

Hypertension is absolute contraindication to use of epinephrine in treatment of anaphylaxis symptoms are the most common clinical manifestation of anaphylaxis

. Indicate a dose of adrenaline for children in treatment of anaphylaxis:

0,15 mg/kg subcutaneous

B. 0,01 mg /kg subcutaneous

0,15 mg/kg intramuscular

0,01 mg/kg intramuscular

Symptoms of recurrent (biphasic) anaphylaxis -occurs.../after the initial attack

1 - 2 hours

8-10 hours

48h

None of them

All of the following treatment are helpful in atopic dermatitis except:

Cyclosporine

Dupilumab

Omalizumab

Pimecrolimus

Atopic dermatitis skin is more susceptible except:

Skin infections

Red dermogrhism

Dehydration

Hypopigmentation

Topical steroids. Find not true:

After 2 weeks of treatment may observed rebound effect

It's the best treatment in acute eczema

May cause hypopigmentation

Is the second line of treatment in atopic dermatitis

Inhibitor ACE(antihypertensive medicine)-find false:

Caused hereditary edema

Very often have cross reaction with ASA

Very often causes swollen tongue

Often causes swollen genitals

Contraindications to the patch test include

Atopic dermatitis

Acute eczema

Anaphylaxis

Uncontrolled asthma

Chronic urticaria is often caused by

Cancer

Animal saliva

Larynx infection

Autoimmune disease (eg. thyroid)

Find the right answer.Cold urticaria is

could be caused by cold weather outside

Typically localized on the forearms,chest,neck

is caused by hashimoto disease

Typical for young women

Treatment of chronic AR,choose the best combination:

Which cells play an important role in asthma?

Mast cells, macrophages

Eosinophils, neutrophils

T lymphocyte, epithelial cells

All above

Symptoms of asthma includes usually:

Cough & wheezing

Cough by 7 day (only) after virus infection

Loss of libido

Obturation in spirometry in asthmatic patients, you can recognise:

FEV1%/FVC SR below (-1,64)

FEV1%/FVC percentile above(5)

FEV1%/FVC below highest value

All of the above

. Type I - IgE mediated, non atopic allergy include:

Wasp venom allergy

Pollen allergy

Fluoroquinolones hypersensitivity

None

Choose type 2 hypersensitivity reactions:

Haemolytic anemia taking some medicine

Leukocytopenia after taking NSAID

Thrombocytopenia after taking some medicine

All of them

Cross reaction between penicillin and cephalosporin:

Penicillin and I gen cephalosporin 60%

2. Penicillin and II gen cephalosporin =20 %

penicillin and III gen cephalosporin <1 %

Penicillin and I gen cephalosporin =16 %

Penicillin and II gen cephalosporin =2 %

Penicillin and IV gen cephalosporin =50 %

Drug allergy- most common symptoms include:

Skin reactions

Anaphylaxis

Respiratory symptoms

Cardiovascular system

NSAID hypersensitivity is connected with:

non allergic hypersensitivity

Nasal polyps

Decreased leukotrienes level

Increased production of prostaglandin E2 level

. Type 3 hypersensitivity reaction include:

Whole body reactions-serum sickness

Whole body reactions-Arthus reaction

Local reactions- allergic alveolitis

local reactions-serum sickness

Which immunoglobulins stimulate complement in type 3 hypersensitivity?

IgM and IgG3

IgA and IgE

IgD and IgG4

IgA and IgG4

The adverse reactions to sulpha drugs in AIDS patients include:

Rash

Nausea

Stevens - johnson syndrome

All above

Show true sentences:

NSAID intolerance prevalence in asthma and nasal polyposis or rhinosinusitis is 30-40%.

Aspirin-induced asthma affects 10% of adults with asthma.

In chronic urticaria, the prevalence of NSAID intolerance is 20-30%.

All above

Aspirin triad include:

ASA hypersensitivity, asthma, nasal polyposis

Rhinorrhea, conjunctival injection, periorbital edema

Nasal polyposis, sinusitis, food allergy

ASA hypersensitivity, asthma, food allergy

Preformed mediators (from mast cells):

Histamine, heparin

Tryptase, kininogenase

Leukotrienes, prostaglandins

Histamine, heparin and tryptase, kininogenase

Step 5 in asthma treatment, GINA recommended

Medium dose ICS +LABA

High dose ICS+LABA

Biological treatment anti IL5, anti IgE before oral steroids

oral steroids GINA recommended as first choice

Asthma in pregnancy women

treatment by inhalers are the same like non-pregnant women

Inhaled steroids are prohibited

Antileukotrienes are first choice

None of the above

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