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Uveitis :->

Uveitis Knowledge Quiz

Test your knowledge on uveitis and ocular diseases with this comprehensive quiz designed for medical students and professionals. With a variety of questions covering anatomy, pathology, and treatment options, challenge yourself and expand your understanding of this important field.

Features:

99 carefully crafted questions
Multiple choice format
Instant feedback on answers

99 Questions25 MinutesCreated by ExaminingEye42

Most sensitive part of eye is:

A. Fovea centralis

B. Macula lutea

C. Blind spot

D. Temporal retina

E. Nasal retina

Which continues to grow in the lifetime:

A. Cornea

B. Iris

C. Lens

D. Retina

A patient with inactive uveitis about 1 year ago, which one of the following types of cataract is most likely to alter a patient spectacle prescription from +3.25 / -0.50 x 75 to +1.00 / -0.50 x 75?

A. Anterior cortical cataract

B. Posterior sub capsular cataract

C. Nucleus cataract

D. Cortical cataract

E. Polar cataract

What is the Sl beam setting used in the SUN grading system

A. 1x2mm

B. 1x3mm

C. 2x2mm

D. 1x1mm

Using a high-power slit beam 2 mm long and 1mm in height with maximal light intensity, you observe approximately 90 cells in the anterior chamber. What grading of AC cells will you give this eye?

A. 3+

B. 1+

C. 2+

D. 4+

E. 0.5 +

The most earliest sign of anterior uveitis is:

A. Aqueous flare

B. Aqueous cell

C. Keratic precipitates

D. Constriction of pupil

E. Raised intraocular pressure

Sign of activity in chronic iridocyclitis is:

A. Aqueous cells

B. Aqueous flare

C. Pigmented KPs

D. Ciliary injection

Separation of rods and cones due to exudative choroiditis causes:

A. Photopsia

B. Micropsia

C. Macropsia

D. Metamorphopsia

Frosted branch angiitis is MOST characteristic of infection with:

A. HIV

B. HSV

C. EBV

D. CMV

E. HZV

Which procedure is most likely to result in post-operative infectious scleritis?

A. Pterygium surgery

B. Cataract surgery

C. Strabismus surgery

D. Glaucoma surgery

The most frequent bacterial agent causing non granulomatous uveitis is:

A. Staphylococcus

B. Streptococcus

C. Pneumococcus

D. Influenza bacillus

12. In complete albinism the colour of iris is:

A. White

B. Black

C. Pink

D. Blue

E. Green

The investigation of anterior uveitis of a young boy is:

A. X-ray of sacroiliac joint

B. TORCH agents

C. ELISA for HIV

D. USG abdomen

True about heterochromic uveitis:

A. Involves posterior surface of iris

B. Involves anterior part of iris

C. Involves posterior chamber

D. Posterior synechiae

What is the MOST common systemic association with scleritis?

A. Systemic lupus erythematosus

B. Polyarteritis nodosa

C. Rheumatoid arthritis

D. Inflammatory bowel disease

E. Wegener's granulomatosis

Granulomatous uveitis with involvement of parotid gland is seen in:

A. Tuberculosis

B. Syphilis

C. Mumps

D. Sarcoidosis

The following drugs are known to cause uveitis :except

A. rifabutin

B. cidofovir

C. methotrexate

D. latanoprost

What antiviral therapy is ineffective in treatment CMV Retinitis ?

A. IV ganciclovir

B. Oral Valacyclovir

C. Oral Valganciclovir

D. Intravitreal ganciclovir implant

The earliest symptom of sympathetic ophthalmitis is:

A. Pain

B. Decreased distant vision

C. Photophobia

D. Diplopia

E. Decrease accommodation

What therapeutic agent , used in the treatment of severe uveitis , permanently cross links deoxyribonucleic acid ( DNA ) and has the higest risk of secondary malignancy ?

A. Hydroxychloroquin

B. Methothrexate

C. Cyclophosphamide

D. dapson

In an immunocompromised patient with retinitis, a diagnosis of toxoplasma retinitis is favoured over cytomegalovirus (CMV) retinitis by the presence of the followings except:

A. Ocular pain

B. Dense vitreous reaction

C. Retinal haemorrhages

D. Granulomatous anterior chamber reaction

E. Scattered small lesion throughout the posterior segment

What uveitis treatment is contraindicated in patients with uveitis associated with multiple sclerosis ?

A. Tumor necrosis factors alpha inhibitor

B. Cycloplegic

C. Intravitreous corticorsteroid

D. Intravenous corticosteroid

Which of the following clinical features of newly diagnosed idiopathic pars planitis is most predictive of the future development of multiple sclerosis (MS)?

A. Neovascularization of the vitreous base

B. 180 degrees of snowbanking

C. Retinal vascular sheathing

D. Angiographic optic disc oedema

E. Posterior subcapsular cataract

What uveitis disorders, which involve anterior segment inflammation, very rare manifestation with a hypopyon ?

A. Ranibizumab reaction

B. Adamantiaes-Behcet disease

C. HLA-B27 associated with uveitis

D. Pars planitis

Following periocular injection of triamcinolone , what complication unlikely to occur ?

A. Elevated IOP

B. Iris atrophy

C. Ptosis

D. Periocular hemorrhage

What factors is associated with greatest relatives risk for corneal transplant rejection ?

A. Stromal vascularisation of recipient cornea

B. Previous intraocular surgery

C. HLA genotype mismatch

D. Posterior synechia recipient

What systemic medication has been associated with ocular inflammation ?

A. Biphosphonate

B. Acyclovir

C. Ampiciline

D. Thiazidic diuretic

28. For those with primary central nervous system lymphoma (excluding those with HIV infection) , what percentage of patients have intra ocular involvement ?

A. 5%

B. 50%

C. 25%

D. 80%

Cystoid macular edema may commonly be found in posterior ocular inflammations disorders. For what inflammatory condition would reconsider the diagnosis if you found cystoid macular edema?

A. Retinal vasculitis

B. Multiple evanescent white dot syndrome

C. Pars planitis

A 25 year old lady presents with severe sudden onset of pain, corneal congestion, photophobia and deep anterior chamber in the right eye. The left eye is normal. X-ray pelvis shows sacroilitis.

A. Anterior uveitis

B. Posterior uveitis

C. Intermediate uveitis

D. Scleritis

What uveitis therapy has the highest risk of causing secondary glaucoma severe enough to require pressure-lowering surgery ?

A. Oral methothexate

B. Intravitreal triamcinolone 4 mg

C. Periocular triamcinolone injections

D. Intravitreal fluocinolone 0.59 mg implants

Uveal effusion syndrome may be associated with all of the following except:

A. Myopia

B. Ciliochoroidal detachment

C. Structural defect in Sclera

D. Nanophthalmos

Patients with what inflammatory disorder may be benefit most from pars plana vitrectomy ?

A. Serpiginous chorioretinopathy

B. Intermidiate uveitis

C. Anterior uveitis

D. Bartonella neuroretinits

For a patient under 6 years old with unilateral uveitis , what is the primary concern when considering an aqueous or vitreous aspirate ?

A. Risk of general anesthesia

B. Risk of vitreous wicking and / or cataractogenesis

C. Risk of dispersing malignant retinoblastoma cells

D. Risk of sympathetic ophthalmia

What ocular finding is associated with inflammation bowel disease ?

A. Retinal necrosis

B. Retinal vasculitis

C. Primary open angle glaucoma

D. Retinoschisis

What is likely the most effective regimen for preventing or treating perioperative inflammation in uveitis patients undergone cataract surgery?

A. Topical cyclosporine drops

B. Frequent topical corticosteroid drops

C. Intravitreal triamcinolone given intraoperatively

D. Topical nonsteroidal antiinflammatory drops

What essential feature differentiates progressive outer retinal necrosis from acute retinal necrosis ?

A. Concomitant use of corticosteroid

B. Herpes simplex versus herpes zoster infection

C. Presence of HLA-A29 genotype

D. Immunosuppression , typically from human immunodeficiency virus infection

The use of highly active anti-retroviral therapy (HAART) is associated with the development of:

A. Keratitis

B. Uveititis

C. Retinitis

D. Optic neuritis

What is topical corticosteroid medication is most likely to cause a corticosteroid-respond elevation in IOP?

A. Prednisolone acetate 1%

B. loteprenol 0.5%

C. rimexolone 1%

D. Fluromethalone 0.1%

40. What is the most likely immune mechanism of Vogt-KoyanagiHarada syndrome?

A. Th1 and other T-cell- mediated pathways

B. Th2 and other T-cell-mediated pathways

C. antigen-antibody complexes

D. A complement- and polymorphonuclear-cell-mediated process

A major side effect of systemic cyclosporine is

A. Elevated intraocular pressure

B. cataracts

C. osteoporosis

D. Systemic hypertension

Malignant melanoma of the choroid with following histopathological features has got the worst prognosis:

A. Epitheloid cell melanoma

B. Spindle - A melanoma

C. Spindle - B melanoma

D. Mixed cell melanoma

What is the mediator of the anti-inflammatory effects of Methotrexate?

A. Inhibition of folate metabolism

B. Nucleotide cross-linking during DNA replication

C. Inhibition of calcineurin

D. Extracellular release of adenosine

What is the specific concern about using a tumor necrosis factor (TNF) inhibitor in a 25-year-old woman with intermediate uveitis and no evidence of tuberculosis or other systemic disease or infection?

A. Congestive heart failure

B. Risk of neoplasia

C. Lupus like syndrome

D. Demyelinating disease

Chronic postoperative endophthalmitis is most commonly caused by which organism?

A. Candida glabrata

B. Nocardia species

C. Klebsiella pneumoniae

D. Propionibacterium acnes

Which of the following findings is most likely to be seen in a patient with systemic lupus erythematosus?

A. Chronic anterior uveitis

B. Intraretinal hemorrhages and cotton-wool spots

C. Intermediate uveitis

D. Acute anterior uveitis

Which of the following statements most likely applies to a patient newly diagnosed with serpiginous choroiditis?

A. Vasculitis is a prominent feature

B. old, scarred lesions may be present in the newly diagnosed eye

C. Intense vitritis is common

D. multiple, isolated lesions occur, with recurrences

Which clinical finding is associated with acute retinal necrosis?

A. Extensive choroidal scarring

B. Natural history of rapid progression

C. Occlusive vasculopathy mostly involving retinal venules

D. Minimal vitritis

The white dot lesions of which disease are least apparent on fluorescein angiography?

A. Serpiginous choroiditis

B. Punctate inner choroidopathy (PIC)

C. Acute posterior multifocal placoid pigment epitheliopathy (APMPPE)

D. Birdshot retinochoroidopathy

In patients with VKH syndrome, the presence of diffuse choroiditis is most likely to be found during which stage of the disease?

A. recurrent

B. prodromal

C. late (chronic)

D. early (acute uveitic)

What is the triad of reactive arthritis syndrome?

A. urethritis, polyarthritis, and conjuctival inflammation

B. Ulcerative colitis, polyarthritis, and conjunctival inflammation

C. Genital ulcers, polyarthritis, and vasculitis

D. Palmar rashes, pauciarticular arthritis, and fevers

What class of microorganisms has been associated with glaucomatocyclitic crisis?

A. viruses

B. bacteria

C. fungi

D. parasites

What serologic test is most likely to suggest a specific cause of uveitis, may be curative, and must be considered for all patients with uveitis?

A. A treponemal-specific serologic test

B. Antinuclear antibody (ANA)

C. Rheumatoid factor (RF)

D. Antineutrophil cytoplasmic antibody (ANCA)

What is the most common infectious condition or agent associated with neuroretinitis?

A. tuberculosis

B. syphilis

C. Bartonella henselae

D. toxoplasmosis

A patient with uveitis and strongly positive rapid plasma regain (RPR) and fluorescent treponema antibody absorption (FTA-ABS) tests has a history of resolved penile chancre, and recently developed a rash on his palms. What is the most likely diagnosis?

A. Primary syphilis

B. false-positive FTA-ABS result

C. Secondary syphilis

D. Tertiary syphilis

The following conditions can give rise to both uveitis and erythema nodosum :except

A. Crohn's disease

B. Behcet's disease

C. sarcoidosis

D. Rheumatoid arthritis

When submitting a vitreous biopsy specimen to rule out intraocular lymphoma, the most important factor that will ensure the highest chance of obtaining reliable information is A. Preoperative magnetic resonance imaging (MRI) to determine if central nervous system (CNS) lesions exist

A. Preoperative magnetic resonance imaging (MRI) to determine if central nervous system (CNS) lesions exist

B. Preoperative consultation with the ophthalmic pathologist

C. Obtaining a large enough specimen to allow vitreous cytokine analyses

D. Performance of polymerase chain reaction (PCR) studies to determine

Heavy chain rearrangement

Which of the following immunomodulatory agents belongs to the T-cell inhibitors?

A. azathioprine

B. cyclophosphamide

C. tacrolimus

D. infliximab

What percentage of Ant uveitis has cystoid macula oedema as a complication?

A. 1%

B. 5%

C. 15%

D. 25%

Which of the following patients is the most likely to have primary CNS! Intraocular lymphoma?

A. a 40-year-old man with cotton-wool spots and hard exudates

B. a 59-year-old man with hemorrhagic retinitis and retinal vasculitis

C. a 65-year-old woman with dense vitritis, subretinal infiltrates, and mental confusion

D. a 29-year-old woman with pars plana exudates and retinal vasculitis

The following HLAs are associated with an increased incidence of uveitis:except

A. HLA-B27

B. HLA-A29

C. HLA-B51

D. HLA-A1

E. HLA-DW5

An individual infected with the human immunodeficiency virus (HIV) has a necrotizing retinitis. Which of the following tests would be most helpful in making the diagnosis?

A. Blood and urine cultures for herpes viruses, including CMV

B. Vitreous biopsy for polymerase chain reaction evaluation, cultures, and cytologic testing

C. Purified protein derivative testing for tuberculosis

D. Serologic testing for herpes viruses, including CMV

What is the most common intraocular infection in patients with AIDS?

A. Acute retinal necrosis

B. toxoplasmosis

C. candidiasis

D. CMV retinitis

The following are true about TINU (tubulointerstitial nephritis uveitis) syndrome:exept

A. The median age is 15 years of age.

B. Females are more frequently affected than males.

C. Sarcoidosis is the most common cause

D. The most common type of uveitis in TINU syndrome is bilateral anterior uveitis

What test may suggest a specific surgical approach to persistent macular edema in an eye with a long-standing (several years' duration) intermediate uveitis that has no active inflammation under treatment with immunosuppressive agents?

A. Fluorescein angiography

B. MRI of the head and orbit

C. Optical coherence tomography (OCT)

D. Lyme titers

Which form of juvenile idiopathic arthritis is most likely to be associated with anterior uveitis?

A. Pauciarticular

B. ANA-; RF+

C. Still's disease

D. Polyarticular

Posner-Schlossman syndrome:

A. Is painless

B. Does not cause glaucomatous field loss

C. Is associated with hypopyon in the majority of cases

D. Is a self-limiting condition

E. Should be treated with systemic steroid

Initial treatment should not include immunomodulatory therapy in addition to corticosteroids for which of the following?

A. Wegener's granulomatosis

B. Sarcoidosis

C. Mucous membrane pemphigoid

D. Behcet's disease

In Fuch's heterochromic cyclitis: except :

A. Koeppe's nodules are seen

B. Abnormal vessels are seen bridging the angle of the trabecular meshwork

C. Cataract is seen in 50% of the cases

D. There is an increased vitreous loss during phacoemulsification

Puff-balls opacities in the vitreous are pathognomonic of:

A. Fungal endophthalmitis

B. Pars planitis

C. Exudative retinopathy of Coats

D. Sympathetic ophthalmitis

What is the life stage of Toxoplasma gondii associated with reactivated disease?

A. Tachyzoite

B. Cystozoite

C. Oocyst

D. Bradyzoite

The following immunosupprassants and their side-effects are true: except

A. cyclophophamide - haemorrhagic cystitis

B. cyclosporine - bone marrow dysplasia

C. methotrexate - hepatic fibrosis

D. tacrolimus (FK506) – hyperglycaemia

Which of the following disorders is not always bilateral?

A. Pars planitis

B. Vogt-Koyanagi-Harada disease

C. Birdshot chorioretinopathy

D. Sympathetic ophthalmia

In the treatment of CMV retinitis: except:

A. ganciclovir, foscanet and cidofovir are all virostatic

B. Ganciclovir causes bone marrow suppression

C. Foscanet is associated with renal impairment

D. Cidofovir is associated with hepatic dysfunction

What is the predominant cell type seen in the anterior chamber of a patient with phacolytic uveitis and glaucoma?

A. Neutrophil

B. T-lymphocyte

C. Macrophage

D. Eosinophil

The following are true about cytomegaloviral retinitis:except

A. It is rarely seen in patients with a CD 4+ counts of more than 50 cells/ul

B. It causes full thickness retinal necrosis

C. Frosted branch retinitis is a known clinical feature

D. Spontaneous resolution in about 30% of patients without treatment

What would the differential diagnosis for isolated intermediate uveitis not include?

A. Reactive arthritis

B. Primary CNS lymphoma

C. Multiple sclerosis

D. Lyme

The 'white dot' lesions of which disease is least apparent on fluorescein angiography?

A. Birdshot chorioretinopathy

B. Serpiginous choroiditis

C. Punctate inner choroidopathy (PIC)

D. Acute posterior multifocal placoid pigment epitheliopathy (APMPPE)

Early findings in Vogt Koyanagi Harada (VKH) syndrome does not include which of the following?

A. Tinnitus

B. Granulomatous anterior segment inflammation

C. Vitiligo

D. Bilateral serous retinal detachments

Which of the following uveitic conditions is most likely to present with a white and asymptomatic eye?

A. Herpetic anterior uveitis

B. Acute retinal necrosis syndrome

C. Wegener's granulomatosis

D. Juvenile idiopathic arthritis-associated uveitis

Which of the following is a preferred method of treatment in a patient with primary central nervous system/intraocular lymphoma?

A. Systemic corticosteroid therapy

B. Systemic chemotherapy

C. Intrathecal methotrexate and local radiopathy

D. Local radiopathy

Which of the following patients is most likely to have scleritis?

A. A 40-year-old male with red eye and throbbing eye pain with weight loss and non-healing skin lesions

B. A 30-year-old woman with red eye and blurred vision

C. A 56-year-old woman with foreign body sensation and red eye

D. A 73-year-old male with red eye and decreased vision with ipsilateral headaches and jaw pain

In Schwartz's syndrome:

A. There is raised intraocular pressure

B. Granulomatous uveitis is a feature

C. There is forward movement of the lens-iris diaphragm

D. Macular oedema is a main cause of visual loss

Which of the following statements best describes the epidemiology of scleritis associated with collagen vascular disease?

A. Men are more commonly affected than women.

B. Bilateral involvement is seen only rarely.

C. About half of the patients have an underlying systemic medical condition.

D. It is most common in third decade.

Most patients presenting with acute anterior non granulomatous anterior uveitis will require treatment with which of the following?

A. Topical corticosteroids and cycloplegic agents only

B. Periocular corticosteroids injections

C. Oral corticosteroids

D. Immunosuppressive agents orally

Which of the following patients is most likely to have primary central nervous system/intraocular lymphoma?

A. A 59-year-old male with hemorrhagic retinitis and retinal vasculitis

B. A 29-year-old female with pars plana exudates and retinal vasculitis

C. A 40-year-old male with cotton wool spots and hard exudates

D. A 65-year-old female with dense vitritis, subretinal infiltrates, and mental confusion

Which of the following is a complication of punctate inner choroidopathy?

A. Choroidal neovascularization

B. Optic atrophy

C. Cystoid macular edema

D. Retinal detachment

Which of the following clinical features are more common in scleritis than episcleritis?

A. It blanches in response to topical phenylephrin, while episcleritis does not

B. It is potentially progressively destructive and sight threatening if left untreated

C. It is simple or nodular, and is not associated with systemic collagen-vascular disease

D. Minimal tenderness compared with episcleritis

Mycophenolate mofetil is not appropriate for treatment of which of the following conditions?

A. Fuchs’ iridocyclitis syndrome

B. Birdshot retinochoroidopathy

C. Sympathetic ophthalmia

D. Rheumatoid arthritis-associated scleritis

Which of the following statements best describes the typical fundus findings of serpiginous choroiditis?

A. Old, scarred lesions may be present in the newly-diagnosed eye.

B. Intense vitritis is common.

C. Multiple, new, isolated lesions occur with recurrences.

D. Vasculitis is a prominent feature.

Which of the following is the most appropriate treatment for a 30-year-old man with sinus inflammation, bilateral scleritis, mild anterior uveitis, and a positive anti-neutrophilic cytoplasmic antibodies (c-ANCA) test?

A. Oral non-steroidal, anti-inflammatory agents such as indomethacin at 50 mg tid

B. Topical non-steroidal anti-inflammatory agents such as ketralac

C. Injection of 40 mg of periocular triamcinolone actetate

D. Oral cyclophosphamide at 2 mg/kg/day

In which of the disorders below is indocyanine green (ICG) angiography most useful?

A. Pars planitis

B. Primary central nervous system/intraocular lymphoma

C. Posterior scleritis

D. Serpiginous choroiditis

The following medications are effective against toxoplasma tissue cysts:

A. clindamycin

B. pyrimethamine

C. sulphonamides

D. azithromycin

The matching of the following diseases and their HLA association are true:except

A. Sympathetic ophthalmitis : HLA-A11

B. Par planitis: HLA-DR2

C. Cicatricial pemphigoid: HLA-B5

D. Posner-Schlosmann syndrome: HLA-BW5

E. Vogt-Koyanagi-Harada: HLA-B22

What infectious agent has been associated with Fuchs heterochromic iridocyclitis?

A. Syphilis

B. Rubella

C. Herpes simplex

D. Herpes zoster

Severe vitritis is a feature of:

A. Cytomegalovirus retinitis

B. Serpigionous choroidpathy

C. Presumed ocular histoplasmosis

D. Toxoplasma retinochoroidopathy

98. The following are true about active ocular toxoplasmosis:

A. The antibodies are always present

B. The central nervous system should be evaluated for toxoplasmosis in all immunocompromised patients

C. Indocyanine green can be used to detect clinically invisible active satellite lesions

D. The border of the lesion is sharply defined

E. It is the commonest cause of retinitis in AIDS patients

Which of the following is NOT a recognised feature of Behcet's disease ?

A. Oral aphthous ulcers

B. Pulmonary artery aneurysm

C. Genital ulcers

D. Erythema nodosum

E. Sensorineural deafness

Which is NOT a feature of progressive outer retinal necrosis (PORN)?

A. Early macular involvement before the peripheral retina

B. unilateral

C. Poor visual prognosis even with early foscarnet and ganciclovir treatment

D. immunocompromised

E. High incidence of retinal detachment

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