Biochem Quiz (Final)

A detailed illustration of biochemical pathways with emphasis on enzymes and metabolic processes, colorful and educational style

Biochemistry Mastery Quiz

Test your knowledge of biochemistry with this comprehensive quiz designed for students and professionals alike. Challenge yourself with questions covering key enzymes, metabolic pathways, and biochemical processes. Perfect for those preparing for exams or simply looking to refresh their knowledge.

Multiple choice questions
Covers various biochemistry topics
Enhance your understanding of metabolic pathways

50 Questions12 MinutesCreated by DecodingScience42

Cytcchrome C oxidase is also called ----------- of the electron transport chain.

Complex III .

Complex I .

Complex II .

Complex IV.

All of the following about (Electron Transport Chain Inhibitors) true except:

UCP1 called Thermogenin and found primarily in brown adipose tissue.

Oligomycin is considered an example of Respiratory Inhibitors.

2,4 Dinitophenol is considered an example of Uncouplers Inhibitors

Respiratory Inhibitors inhibit the ETC by taking the the (H+) from intermembrane space and then release it into the Matrix.

All of the following about (Glycogen Synthase) true except:

It makes only (1-4) bonds.

Add glucose only to the non-reducing End .

It takes glucose molecules from UTP-Glucose and bind them together.

It needa primer to work.

Regarding Glycogen structure, all of the following true except:

It is Homopolysaccharide of (alpha-L-Glucose) .

Stored in cytoplasm as granules that contain all the enzymes for its Synthesis and degradation.

Liver glycogen serves all the body .

Muscle glycogen used only by muscle during exercise.

A common Enzyme that is important for Glycogen synthesis and Degradation, is:

Pyrophosphatase.

Glucose-6-Phosphatse.

Phosphoglucomutase.

( a+c).

The enzyme that makes human enable to go in alcoholic fermentation is?

Pyruvate decarboxylase

Alcohol dehydrogenase

1+2

Pyruvate carboxylase

Which of the following statements regarding TCA cycle is true?

It is anaerobic process

It occurs in cytosol

It generates 10 molecules of ATP per cycle

None of the above is true

Substrates level phosphorylation in TCA cycle is in step

Isocitrate dehydrogenase

Malate dehydrogenase

Aconitase

Succinate thiokinase

The rate limiting enzyme at TCA cycle is :

Succinate thiokinase

Isocitrate dehydrogenase

α-Ketoglutarate dehydrogenase complex

Malate dehydrogenase

Regarding type V (Mcardle disease) of glycogen storage disease, it is caused by:

Skeletal muscle glycogen phosphorylase deficiency.

Hepatic glycogen phosphorylase.

Deficiency of debranching enzymes.

Deficiency of Lysosomal α(1→4) glucosidase.

G1-P is converted to G6-P by the activity of:

Oligo-α(1→4) → α(1→4) glucantransferase.

Pshosphoglucomutase.

Glucose 6-phosphate translocase.

Glucose 6-P phophatase.

Which of the followings enzymes found only in liver?

CPS-1

Arginase

Argininosuccinate synthetase

Argininosuccenate lyase

In cardiac PFKII, when is the kinase domain activated?

When it is dephosphorylated

When it is phosphorylated

High glucagon/insulin ratio

Substrate-level phosphorylation

Which one of the following sentences is correct :

Isomers of sugers that differ in bond patterns are called epimers

The number of chiral carbons in Dihydroxyacetone is zero

The simplest suger contains only 2 carbons

Cyclic form of suger lose a chiral carbon compared to the open chain form

Chitin is a homopolysaccaraides that consists of:

N_Acetyl_B_D_Galactoseamine

N_Acetyl_B_D_glucoseamine

B_D_Glucose

N_Acetyl_B_L_glucoseamine

All the following are true except:

Diasereomers are non mirror images

Aldopentose contains4 pairs of enantiomers

D_Glucose and L_Galactose are epimers at C4

The process of interconverted anomers in aqueose solution is called mutarotation

At which of the following substrate concentration values will the reaction velocity (V) be equal to 4/11 Vmax

[S] = ½ Km

[S] = 4/7 Km

[S] = 4/11 Km

[S] = 2/3 Km

Which of the following statements is true regarding Lineweaver-Burk plot:

When adding a noncompetitive inhibitor to the reaction , the y-axis interception point changes and the slope decreases

When adding a competitive inhibitor to the reaction , the y-axis interception point changes and the slope increases

When adding an uncompetitive inhibitor to the reaction , the x-axis interception point doesn’t change and the slope is equal to the original

When adding a noncompetitive inhibitor to the reaction , the x-axis interception point doesn’t change and the slope increases

Myocardial infarction is a disease that can be detected when cardiac troponin and CK-2 are present in high levels, with lower levels of cardiac troponin

True

False

Given the ∆G’° for the reaction S⇋P is negative in the direction of S→P, reaction equilibrium favors the formation of which substance in standered condition ?

The reaction proceeds equally in both directions

The reaction does not proceed in either direction

What relative values of Km and Kcat would describe an enzyme with high catalytic efficiency ?

Low Km and low Kcat

High Km and low Kcat

Low Km and high Kcat

High Km and high Kcat

A person was admitted to the ER with severe symptoms, when his results came back ,it turns he has high ALT , so ha may have :

Myocardial infarction

Muscle disorder

Liver disease

We can’t tell

All of the urea cycle disorders follow an autosomal-recessive inheritance pattern EXCEPT:

Ornithine transcarbamoylase

Arginase

Argininosuccinate synthatase

CPS1

One of the following is used to buffer ammonia & produce Lactic & acetic acids :

Lactose

Neomycin

Lactulose

Phenylbutrate

How would the addition of a catalyst to the reaction S⇋P affect the difference between the free energies of S and P in their ground states ?

The change in ∆G’° cannot be predicted without more information.

)∆G’° would not change

)∆G’° would become less negative

�G’° would become more negative

According to white blood cell phagocytosis, which one of the following enzymes is mismatched?

Lysosomal enzymes - - - oxygen indepedent mechanisms

NADPH oxidase - - - O2 reduced to superoxide

Superoxide dimutase---oxidized superoxide

MPO - - - convertion H2O and Cl- to HOCL

Fe+2---reduced H2O2 to Hydroxyl radical

If you have patient with assymptomatic homozygous mutation that causes G6FD deficiency, And all the following sentences describe the deficiency except :

NOT enough NADPH is made in his RBCs

Denaturation of the membrane proteins of his RBC because Heinz bodies will be formed

Mutation does no show clinical manifestation evenlf he eats fava beans

His RBCs cannot renew their supply of the enzyme G6PD

Gluconeogenesis occurs in the liver and kidney. Which is of the following enzymes are important for gluconeogenesis are expressed exclusively in these tissues?

Glucose-6-phosphatase

Fructose-1,6-Bisphosphatase

Phosphoenol pyruvate carboxykinase

Pyruvate carboxylase

If gluconeogenesis started by lactate in coricycle , it Consumes:

6high energy phosphate bonds

2ATP , 2GTP and 2NADH+

2ATP and 2GTP

None of above

During gluconeogenesis, the three irreversible steps of glycolysis have to be bypassed. The first step is the conversion of pyruvate to phosphoenolpyruvate. Which of the following statement is false regarding the reaction step?

Phosphoenol pyruvate utilizes both ATP and GTP as energy source.

Conversion of oxaloacetate from pyruvate occurs in mitochondria and shuttled into cytosol.

This reaction involves two step process catalyzed by pyruvate carboxylase and phosphoenolpyruvatecaboxykinase

Acetly CoA is an activator of enzyme pyruvate carboxylase

Which of the following statements about gluconeogenesis is correct?

Pyruvate is first converted to phosphoenolpyruvate by phosphoenolpyruvatecarboxykinase

Fructose 1, 6-biphosphatase converts fructose 1, 6-bisphosphate into fructose 1-phosphate

Glucose 6-phosphatase hydrolyzes glucose 6-phosphate to release glucose into the blood

Glucose 6-phosphatase hydrolyzes glucose 6-phosphate and is found in liver and muscle

Which one of the following statments is correct according to citrate shuttle?

Pyruvate is converted to acetyl CoA in the cytosol by PDHC

Citrate is converted to Acetyl CoA and Oxaloacetate by yielding ATP molecules

Isocitrate can not be converted to a-ketoglutarate when the level of ATP is low

Oxaloacetate is converted to malate then to pyruvate by malate dehydrogenase, malic enzyme respectively

Sources of NADPH are glycolysis, ppp and malic enzyme

Acytel CoA carboxlase is converted acytel CoA to Malonyl CoA, which one of the following is the active form of this enzyme?

Dimer, low Citrate,phosphorylation and high insulin

Polymer, dephosphorylation, High calories and High insulin

Polymer, long chain fatty acyl CoA and High glucagon

Dimer, dephosphorylation, High AMP

Which one of the following sentences is correct according to Methioine cycle and folate cycle?

The process of converting Methioine to SAM hyddrolysis 2 Pi bonds in ATP

If there is deficiency of methioine, Homocysteine will be transsulfuration by B6 & Cystathionine synthase

) N5, 10 methylene THF converts dTMP to dUMP when Serine donates a C fragment to THF

The end productd of transsulfuration are Non essential amino acid and intermediate in TCA cycle

If there is a deficiency in B12, DNA synthesis will not be effected

Which one the following treatment is the best to prevent growth of cancer cell ?

Use drug that inhibits dihydrofolate reductase

Use drug that inhibits Ribonucleotide reductase which converts UDP to dUDP

Use drug that inhibits Ribonucleotide reductase which can UDP or UMP as substrate

Methotetroxate

A+D

If you have a patient who dose not eat animal products and he has megaloblastic anemia, so he has deficiency in...... Becauses of acumlation ......... .

The site where we find both HMG synthase and thiophorase is:

Liver

Kidney

Skeletal muscles

All extrahepatic tissues

How much ATP can be produced by complete oxidation of stearic acid and oleic CoA (respectively)?

148, 146

146, 148

146, 144

Equal

One of these statements is wrong about the brain

Glucose enters brain cells via facilitated transport

The brain uses ketone bodies as a major energy source

The brain doesn't be affected directly by insulin levels

FAs can't be metabolized via brain although its cells have mitochondria

One of these statements isn't correct

Vegetarians usually have lower pH than normal due to B12 deficiency

The activation of MCFA occurs in the mitochondria by using what equals 2ATP

Hyperglycemia may lead to ketoacidosis and dehydration

Metabolism of the Long chain saturated fatty acid has the highest produced energy

One of these FAs requires the below enzymes to be completely metabolized B- hydroxy acel CoA, FAD-containing acyl CoA dehydrogenase and Enol CoA isomerase

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