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LIVER FUNCTION

Type of cell responsible for the regenerative property of liver.
Hepatocyte
Kupffer cell
What is the principal pigment of bile?
Which liver function is responsible for metabolism of bilirubin?
Synthetic function
Conjugation function
Storage function
Detoxification and Drug metabolism
Excretory and Secretory function
Which liver function serves to protect that body from potentially injurious substances absorbed from the intestines and toxic by-products of metabolism?
Synthetic function
Conjugation function
Detoxification and Drug metabolism
Excretory and Secretory function
Storage function
Liver function responsible for the elimination of bile acids/salts, pigments, and cholesterol.
Synthetic function
Detoxification and Drug metabolism
Storage function
Excretory and Secretory function
Conjugation function
Liver function involve in the metabolism of cholesterol to bile acids.
Synthetic function
Conjugation function
Secretory and Excretory function
Detoxification and Drug metabolism
Storage function
Principle of Kjeldahl Method
Measurement of nitrogen content of protein.
Oxidation of phenolic compounds to give a deep blue color.
Measurement of refractive index of solutes in serum.
Migration of charged particles in an electrical field.
Principle of Folin-Ciocalteu Method
Measurement of nitrogen content of protein.
Oxidation of phenolic compounds to give a deep blue color.
Measurement of refractive index of solutes in serum.
Migration of charged particles in an electrical field.
Principle of Serum Protein Electrophoresis
Measurement of nitrogen content of protein.
Oxidation of phenolic compounds to give a deep blue color.
Measurement of refractive index of solutes in serum.
Migration of charged particles in an electrical field.
Cupric ions form a complex with peptide bonds, forming a violet-colored chelate which is proportional to the number of peptide bonds present.
Kjeldahl Method
Biuret Method
Lowry Method
UV Absorption Method
Formation of a uniform fine precipitate which scatters incident light suspension.
Turbidimetric Method
Nephelometric Method
UV Absorption Method
Biuret Method
Formation of a uniform fine precipitate which blocks light.
Turbidimetric Method
Nephelometric Method
UV Absorption Method
Biuret Method
Oxygen rich
Hepatic artery
Portal vein
Nutrient rich
Hepatic artery
Portal vein
True/False: Liver has the ability to regenerate.
True/False: Liver needs to be at least 75% destroyed to stop functioning.
Most commonly used dye method.
Bromcresol green
Bromcresol purple
Methyl orange
Hydroxyazobenzene benzoic acid
True/False: The concentration of of albumin is proportional to the severity of the liver disease.
INCREASED Total Protein (3)
Malignancy
Multiple myeloma
Waldenstrom's macroglobulinema
Hepatic cirrhosis
Nephrotic syndrome
Starvation
DECREASED Total Protein (4)
Nephrotic syndrome
Starvation
Multiple myeloma
Waldenstrom's macroglobulinema
Hepatic cirrhosis
Malignancy
MATCHING TYPE: Abnormal SPE Pattern and its Related Disorder
Alpha 1-globulin flat curve
Nephotic syndrome
Beta-gamma bridging
Juvenile cirrhosis
Gamma spike
Multiple myeloma
A1,A2,beta globulin band spikes
Inflammation
Alpha 2-globulin band spike
Hepatic cirrhosis
Widely used for detection of peptides and amino acids after paper chromatography; produces a violet color by reacting with primary amines.
Ninhydrin
Coomasie brilliant blue
Biuret
Lowry
Used for detection of proteins to as little as 1 ug.
Coomasie brilliant blue
Ninhydrin
Biuret
Lowry
Formula for total protein.
End product of hemoglobin metabolism.
Conjugated bilirubin tightly bound to albumin.
MATCHING TYPE: Urobilinogen
Feces
Urobilin
Urine
Stercobilin
Characterized by yellow discoloration of the skin, sclerae, and mucus membranes.
Too much destruction of RBCs.
Hemolytic jaundice
Obstructive jaundice
Hepatocellular combined jaundice
Failure of bile to flow or reach the intestine.
Hemolytic jaundice
Obstructive jaundice
Hepatocellular combined jaundice
Hepatocyte injury caused viruses, alcohol, parasites.
Hemolytic jaundice
Obstructive jaundice
Hepatocellular combined jaundice
Characterized by impaired cellular uptake of bilirubin.
Gilbert's syndrome
Crigler-Najjar syndrome
Dubin-Johnson syndrome
Lucey-Driscoll syndrome
Rotor syndrome
Characterized by the absence of UDPGT.
Gilbert's syndrome
Crigler-Najjar syndrome
Dubin-Johnson syndrome
Lucey-Driscoll syndrome
Rotor syndrome
Blockage of the excretion o bilirubin into the canaliculi caused by hepatocyte membrane defect.
Gilbert's syndrome
Crigler-Najjar syndrome
Dubin-Johnson syndrome
Rotor syndrome
Lucey-Driscoll syndrome
May be caused by a circulating inhibitor of bilirubin conjugation in the baby's or mother's blood.
Gilbert's syndrome
Crigler-Najjar syndrome
Dubin-Johnson syndrome
Rotor syndrome
Lucey-Driscoll syndrome
Distinct feature: Porphyrinuria
Gilbert's syndrome
Crigler-Najjar syndrome
Dubin-Johnson syndrome
Rotor syndrome
Lucey-Driscoll syndrome
MATCHING TYPE: Derangement of Bilirubin Metabolism
Lucey-Driscoll syndrome
Bilirubin Excretion Deficit
Crigler-Najjar syndrome
Conjugation Inhibitor Syndrome
Dubin-Johnson syndrome
Mixed Hyperbilirubinemia
Gilbert's syndrome
Conjugation Deficit syndrome
Rotor syndrome
Bilirubin Transport Deficit
Reagent for bilirubin assays.
Principle of urobilinogen.
Most commonly used method for bilirubin measurement.
Jendrassik and Grof
Evelyn and Malloy
Bromsulphthalein Dye Excretion Test
End product/final reaction for Jendrassik and Grof.
End product/final reaction for Evelyn and Malloy.
Most widely used method in the measurement of total serum protein, which requires at least two peptide bonds and an alkaline medium.
Biuret method
Folin-Ciocalteu
Berthelot method
UV absorption
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