Antineoplastic Agents

What are characteris!cs of cell cycle-- nonspecific (CCNS) an!neoplas!c drug are true? 1. Effect cells randomly at any point of the cell cycle 2. Great for treatment of slow growing cancer that have many cells in the res!ng phase 3. Toxic to cells passing through a specific phase of a cell cycle. 4. Cannot harm cells in the res!ng phase.

A client with a sarcoma is receiving Bleomycin (Blenoxane). The nurse in charge for the client knows that an!cancer drug has major effects on what phase of the cell cycle?

The nurse is monitoring a pa!ent receiving an Iv infusion of an an!neoplas!c medica!on. During the infusion, the pa!ent complains of pain and redness at the inser!on site. The nurse should take which ac!ons? Select all that apply. 1. Reinsert the IV at a distal part of the same vein. 2. Increase the flow rate of the medica!on. 3. No!fy the physician. 4. Apply a heat or ice compress to the site. 5. Administer an an!dote as prescribed.

A client is receiving Methotrexate (Rheumatrex) for a series of chemotherapy. Which of the following medica!on should be readily available to avoid toxicity?

Which of the following is least likely the side effects of chemotherapy.

The goal of tradi!onal an!neoplas!c drug therapy is to a. Reduce the size of abnormal cell mass for immune system destruc!on. b. Eradicate all of the abnormal cells that have developed. c. Destroy all cells of the origina!ng type. d. s!mulate the immune system to destroy the neoplas!c cells

Cancer treatment usually occurs in several different treatment phases. In assessing the appropriateness of another round of chemotherapy for a par!cular pa!ent, the nurse would evaluate which of the following as most important? a. Hair loss b. Bone marrow func!on c. Anorexia d. Heart rate

An!neoplas!c drugs destroy human cells. They are most likely to cause cell death among healthy cells that a. Have poor cell membranes. b. Are rapidly turning over. c. Are in dormant !ssues. d. Are across the blood–brain barrier.

It is important to explain to women that chemotherapeu!c agents should not be used during pregnancy because; a. The tendency to cause nausea and vomi!ng will be increased b. Of poten!al serious adverse effects on the rapidly mul!plying cells of the fetus. c. Bone marrow toxicity could alter hormone levels. d. pa!ents may be weakened by the drug regimen.

5-FU, Flourouracil is a mainstay of treatment for a variety of cancers, it belongs to the classifica!on of: