Histology 4B

A detailed illustration of male reproductive system histology, featuring seminiferous tubules, Leydig cells, Sertoli cells, and accessory glands, in a vibrant and educational style

Explore Male Reproductive Histology

Test your knowledge of the histological structures and functions of the male reproductive system with this comprehensive quiz. Delve into the details of cells, glands, and processes involved in spermatogenesis and hormone production.

35 detailed questions
Multiple choice answers for thorough understanding
Ideal for students and educators

35 Questions9 MinutesCreated by StudyingCells2023

What is true regarding leydig cells?

Lie between the testis cords

By the 8th week of gestation they begin the production of testosterone

Are derived from mesenchyme of the genital ridge

Lie in the medulla of the testis cords

Are derived from mesoderm

Are located in the semiferous epithelium and are called sertori cells

Are haploid

Is a type of germ cell

Leydig cells:

Are controlled by FSH

Express receptor for FSH

Can be found in the epididymis

They release testosterone under stimulation of human chorionic gonadotropin; hCG

Are located in the interstitial tissue of the testis

Are derived from mesoderm

The interstitial tissue of the testis:

Epithelium contains cuboidal and columnar cells

Connects straight tubules to channels of rete testis

Does not contain lymphatic vessels

Is found between semiferous tubules

Contains endocrine interstitial gland; leydig cells

Contains macrophages, fibroblasts, leydig cells and mast cells in loose CT

Are rich in lymphatic bessels and blood vessels

Interstitial tissue:

Its capillaries participate in the formation of the blood-testis barrier

Contains reticular tissue

Surrounds the surface of the testis

Is also called the tunica albuginea

Accessory glands in male reproductive system:

Includes seminal vesicles, prostate and bulbourethral glands

Prostate is surrounded by fibroelastic capsule rich in smooth muscle

Prostate is composed of three zones: central, peripheral and transitional

Prostate is surrounded by skeletal muscles

The prostate consists of two highly tortuous tubes

Glands of prostate are lined with columnar pseudostratified epithelium

Fructose is the main component of prostate fluid

Accessory glands:

Produce secretion

Mucosa of seminal vesicles are lined with cuboidal or pseudostatified columnar epithelium

Only a small volume of human ejaculate originates in seminal vesicles

Bulbourethral glands are the biggest accessory gland

Secretion of bulbourethral gland is rich in sialoproteins

Bulbourethral glands are tubuloalveolar glands

Testis:

Each lobule of the testis consist of one to four semiferous tubules

The tunica albuginea is a thick dense CT which covers each testis

Semiferous tubules are also called straight tubules

Semiferous epithelium conatins only one layer of cells

The testis is divided into lobules by connective tissue septa

There are capillaries in the semiferous tubules

In the lumen of seminiferous tubules leydig cells are located

Each semiferous tubules contains semiferous epithelium and is surrounded by lamina propria

Epididymis:

The epithelium is pseudostratified and contains stereocilia

Is divided into caput, corpus and cauda

Caput is the place of storage of spermatozoa

Contributes to the blood-testis barrier

External layer of epididymal wall in cauda contains some layers of smooth muscle cells

In the epididymis, spermatozoa is coated by glycoprotein to mask haloed antigens on their surface

Caput is the place of spermatozoa maturation

Epithelial cells produce ABP

Sertori cells:

Produce ABP

Are supporting cells of the semiferous epithelium

Are haploid cells

LH controls the function of sertori cells

Are somatic supporting cells

The apical parts reach the lumen of the semiferous tubules

Support the development of germcells into spermatozoa

Produce the anti Müllerian hormone

Seminiferous epithelium:

Contains germ cells and sertori cells

Are very well vascularized

Leydig cells are located in the epithelium

Spermatogonia includes spermatogonia Ad, Ap and B

Have receptors for FSH

Germ cells are divided into spermatogonia, spermatocytes and spermatids

Semiferous epithelium:

Spermatogonia Ad are spermatogonial stem cells

Sertoli cells are supporting cells

Spermatogonia B are the first haploid cell

Sertoli cells are regulated by LH

Spermatocytes include primary and secondary

Sertoli cells belong to the spermatogenic lineage

Seminiferous tubules:

Is composed of seminiferous epithelium and lamina propria

Contains germ cells and sertoli cells

There are no blood vessels present

Semiferous epithelium is pseudostratified

Contains sinusoid

Germ cells include spermatogonia, spermatocytes and spermatids

Tubules are convoluted and have the form of loops

What is true regarding the seminiferous tubule?

There are no lymphatic vessels present

Germ cells include sertoli cells and spermatogonia

Leydig cells are located between germ cells and epithelium

Sertori cells of the seminiferous epithelium are supportive

The basement membrane of the epithelium is covered by fibrous connective tissue

Its lamina propria contains myoid cells

Spermatogenesis:

Is the process of formation and production of spermatozoa

Lasts for 74 days

The first meiotic division takes place from the primary to secondary spermatocyte

Secondary spermatocytes enter the first meiotic division

It is only the process of spermatids differentiation

Consists of both meiotic and mitotic division

Has spermatogonia, spermatocytes and spermatid stages

Takes place in the testis

What is true regarding spermatogenesis?

Spermatids undergo modification in sperminogenesis

Spermatogonia Ad, Ap and B are divided by mitosis

Secondary spermatocytes are diploid, with 46 chromosomes

Spermatids undergo mitotic and meiotic division

Primary spermatocytes are the largest of the spermatogenic lineage

It is controlled by androgens

Spermatid phase is morphological differentiation into spermatozoa

Spermatogenesis:

Meiosis phase starts when the primary spermatocytes undergo the first meiotic division

During spermatogonial phase mitosis of spermatogonia takes place

Spermatogenesis Ad undergo modification in spermatogenesis

No cell division occurs during sperminogenesis

Spermatocytes are divided by meiosis

Secondary spermatocytes are haploid with 23 chromosomes

Primary spermatocytes are diploid with 46 chromosomes

Ad dark cells are spermatogonia stem cells

The prostate:

The glands produce prostatic fluid

Its glands are lined with columnar pseudostratified epithelium

Its branched tubuloalveolar glands empty into the prostatic urethra

Constitutes ≈ 70% of the human ejaculate

Fructose is the main component of the secretion

Is surrounded by skeletal muscle

Consists of 30-50 branched tubuloalveolar glands

The prostate:

Is composed of three zones: central, peripheral and transitional zone

It is surrounded by a fibroelastic capsule rich in smooth muscles that forms septa

Consists of two highly tortuous tubes

Its branched tubuloalveolar glands empty into the prostatic urethra

Accessory glands in the male reproductive system:

Include the seminal vesicles, prostate and bulbourethral gland

Includes the spermatic cord

Only a small volume of the human ejaculate originates in the seminal vesicles

Produces secretion

Bulbourethral glands are tubuloalveolar

Mucosa of seminal vesicles are lined with cuboidal or pseudostratified columnar epithelium

Blood-testis barrier:

Within the adluminal compartment there are primary and secondary spermatocytes and spermatids

It divides the semiferous epithelium into two compartments; a basal and adluminal compartment

Isolates haploid cells from its own immunological system

Within the basal compartment spermatogonia and preleptotene spermatocytes are located

Spermatogenesis:

Spermatids undergo modification in spermiogenesis

Primary spermatocytes are the largest cells of the spermatogenic lineage

It is the process of formation of spermatozoa

It is only the process of spermatid differentiation

Seminiferous tubules:

There are no lymphatic vessels in the tubules

Semiferous epithelium is pseudostratified

It is composed of seminiferous epithelium and lamina propria

Sertori cells are supporting cells

Accessory glands:

Include the seminal vesicles, prostate and bulbourethral gland

Mucosa of seminal vesicles are lined with cuboidal or pseudostratified columnar epithelium

There is only a small volume of human ejaculate which originates from seminal vesicles

Bulbourethral glands are tubuloalveolar

Interstitial fluid of testis:

Is found between seminiferous tubules

Contains lymphatic vessels

Contains endocrine interstitial glands

Leydig cells:

Are supporting cells in the seminiferous epithelium

Are germ cells

Produce testosterone

Are controlled by LH

Are found in the lumen of the seminiferous tubules

Mark: structure - function

Seminiferous tubules - spermatogenesis

Ductus deferens - sperm maturation

Efferent ductules - reabsorption of rete testis fluid

Epididymal duct - maturation of spermatozoa in proximal part

Rete testis - sperm transportation

The heuser membrane lines:

The exocoelomic cavity; the primitive yolk sac

The inner surface of the cytotrophoblast

What is true regarding the bilaminar disc?

It is composed of the cytotrophoblast and syncytiotrophoblast

Develops during the 2nd week of embryogenesis

Is differentiated from the trophoblast

Is differentiated from inner cell mass

Is composed of the hypoblast and epiblast

Produces hCG

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Histology 4B

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