Histology cycle 1B
Histology Quiz: Connective Tissues and ECM
Test your knowledge on histology with our comprehensive quiz focused on connective tissues, extracellular matrix (ECM), and adipose tissue. Perfect for students or anyone interested in histology, this quiz provides a thorough review of essential concepts.
- Multiple-choice questions
- Learn about various types of connective tissue
- Assess your understanding of ECM components
Connective tissue proper:
Originates from mesenchyme
Fibroblasts are active cells, fibrocyres are quiescent cells
The surface of plasma cells contains receptors for IgE
Tropocollagen is monomer unit composed of a triple helix of alpha chains of polypeptides
Fibronectin is a component of GAG
ECM:
Is divided into ground substance and fibers
Tropocollagen is aggregated into fibers in the cytoplasm of the cell
Reticular fibers are composed of type III collagen
Hyaluronic acid is a kind of GAG
The main component of elaunin fibers is type IV collagen
What is true regarding adipose tissue?
There are two kinds of tissue
Adipose tissue is avascular
Multilocular adipose tissue is rich in human adults
Leptin is the secretory product of white adipocytes
Cells of multilocular adipose tissue contains abundant brown mitochondria
Adipocytes if white adipose tissue contains one big lipid droplet in the cytoplasm
What is true regarding adipose tissue?
Adipocytes are found in isolated cells, small groups or large aggregates
The distribution of unilocular adipose tissue is determined by age and sex
Unilocular adipose tissue is a large depot of energy for the organism
Unilocular adipose tissue is responsible for lipid storage
The cytoplasm of multilocular adipocytes posesses a great number of lipid droplets
Adipocytes of yellow adipose tissue contains one lipid droplet in the cytoplasm
Intermediate filaments elvelope lipid droplets of adipocytes
Adipocytes of brown adipose tissue contains one lipid droplet in the cytoplasm
What is true about unilocular adipose tissue?
There are two kinds: white and brown
There are no blood vessels in unilocular tissue
Adipocytes of yellow adipose tissue contains one lipid droplet in the cytoplasm
Lipid droplets of adipocytes are enveloped by intermediate filaments
Leptin is the secretory product of white adipocytes
Cells of multilocular adipose tissue contains abundant brown mitochondria
Synthesis of collagen in fibroblast:
Include a lot of posttranslational modifications
Depends on oxygen, iron and ascorbic acid
Aggregation of tropocollagen into collagen fibers take place inside the cytoplasm
Non helical propeptides are present in collagen fibrils to protect its structure
Occurs in intracellular and extracellular environment
What is correct regarding synthesis of collagen fibers?
Hydroxylation of proline and lysine is within the intracellular environment
Formation of covalent cross-links between tropocollagen molecules takes place within the extracellular environment
Co-factors: O2, Fe, vit.C are needed for hydroxylation of proline and lysine
Procollagen is the precursor for tropocollagen
Glycolysation of hydroxyline is within the extracellular environment
Hydroxylation of proline and lysine is within the extracellular environment
What is correct regarding connective tissue?
Fibroblasts and fibrocytes are resident cells
Leukocytes and mastocytes are wandering cells
Hyaluronic acid can bind monomers to form proteoglycans aggregates
Reticular fibers consists manly of type I collagen
Collagen contains unusual amino acids like desmosine and isodesmosine
Choose correct statements:
Differentiation is also named proliferation
Differentiation occurs only during prenatal life
Differentiation can occur postnatally
Monocytes are able to differentiate into macrophages
Nerve cells lose their ability to proliferate and differentiate as well
ECM producing cells in connective tissue:
Lymphoblastic cells
Fibroblasts
Fibrocytes
Mastocytes
Histocytes
In which structure is dense irregular CT found?
Reticular layer of dermis
Protective white layer of eyeball
Papillary layer of dermis
Which feature is characteristic for elaunin fibers?
Around sweat glands and the dermis
Irregular deposits of elastin between microfibrils
Found in the epidermis
Mesenchyme:
Is an embryonic tissue
Mesenchymal cells are precursors for all types of connective tissue cells
Contains ground substance
Little to no ECM
Embryonic mucous connective tissue:
Is rich in ground substance with hyaluronic acid
Is present in the umbilical fold
Can be found in pulp of young teeth
Is referred to as Whartons jelly
Contains very few collagen fibers type I and III
Rich in collagen fibers
A tendon is a type of:
Loose connective tissue
Dense regular elastic tissue
Dense regular collagenous tissue
Dense irregular tissue
Tissue that contains collagen I
Tissue in which cells are located regularly, but collagens are located irregularly
Tissue where fibrocytes are located regularly
Muscle tissue
Connective tissue proper:
Fibroblasts are active cells, fibrocytes are quiescent cells
The surface of plasma cells contains receptors for IgE
Originates from mesenchyme
Leukocytes that migrate from BV are present in connective tissue
In general it consists of cells and ECM
Fibroblasts produce fibers and ground substance of ECM
Is divided into loose and dense CT
Cells of embryonic mesenchymal CT produce type I collagen
The surface of mast cells contains receptors for IgE
Procollagen is composed of three alpha chains
Connective tissue:
Contains ground substance composed of GAG, proteoglycans and glycoproteins
Is derived from mesenchyme
Aggrecan is an example of GAG
Transient cells of CT are for example fibroblasts
Chondroitin sulfate, keratan sulfate, heparan sulfate and hyaluronic acid are examples of GAG
Adipose tissue:
There are two types: white unilocular and brown multilocular
There are no blood vessels in unilocular tissue
Brown adipose tissue changes into yellow tissue
Adipocytes of white adipose tissue contains one big lipid droplet in the cytoplasm
Adipocytes are found in isolated cells, small groups or in large aggregates
Leptin is a secretory product of white adipocytes
Adipose tissue:
Mitochondria of unilocular adipocytes have thermogenin
Cells of multilocular adipose tissue contains abundant brown mitochondria
The distribution of unilocular adipose tissue is determined by age and sex
Unilocular adipose tissue is a large depot of energy
Unilocular adipose tissue is responsible for lipid storage
The cytoplasm of multilocular adipocytes posses a great number of lipid droplets
Which features are characteristic for multilocular adipose tissue?
Many lipid droplets
In humans the tissue is important mainly in the first postnatal life
One large lipid droplet
Is greatly reduced in adulthood
In human newborn the multilocular adipose tissue constitutes 50% of the body weight
What is true about connective tissue?
Collagen fibers are most abundant
Elastic fibers can be stained with orcein and resorcin-fuchsin
Fibroblasts are very metabolic active cells
Basal lamina contains type IV collagen
CT proper:
Its ECM contains fibers and ground substance
ECM is produced by fibrocytes
Fibroblasts are ECM producing cells in the tissue
Leukocytes that migrate from BV are present in CT
Chondroblasts are the main population of cells in the tissue
Fibroblasts can be differentiated into histiocytes
CT proper:
There is no ECM in the tissue
Collagen contains unusual amino acids such as desmosine and indodesmosine
Transient cells of CT are for example fibroblasts
Hyaluronic acid can bind with monomers of proteoglycans to form aggretations
Is avascular
In general consists of cells and ECM
CT proper:
Fibroblasts produce fibers and ground substance of ECM
Originates from mesenchyme
Is divided into loose and dense CT
Dense irregular CT can be found in the dermis
Cells of embryonic mesenchymal CT produce type I collagen
The surface of plasma cells contains receptors for IgE
CT proper:
Fibroblasts are active, fibrocytes are quiescent
The surface of mast cells contains receptors for IgE
Procollagen is composed of three alpha chains
Fibronectin is composed of GAG
Tropocollagen is a monomer unit composed of alpha chains
Cells of embryonic mesenchymal CT produce collagen type I
Macrophages:
Cells that function in phagocytosis of particulate matter
Are derived from monocytes
Kupffer cells are macrophages
Called histocytes in connective tissue
Are derived from basophils
Cells of mononuclear phagocyte system - location
Histocytes - CT
Microglia cells - CNS
Osteoclasts - bones
Kupffer cells - liver
Alveolar macrophages
Dust cells - lung
Which cells located in the CT originate from the bone marrow?
Mast cells
Fibrocytes
Histiocytes
Adipocytes
Macrophages
Mesenchymal stem cells
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