Pharm Exam 1 Practice Quiz

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Pharmaceutical Knowledge Assessment

Test your understanding of essential pharmaceutical concepts with our comprehensive practice quiz designed for aspiring healthcare professionals. Dive into a series of multiple-choice questions covering various topics, including drug classifications, vitamin deficiencies, and treatment options.

Whether you're prepping for an exam or just brushing up on your knowledge, this quiz offers:

In-depth questions tailored to pharmacy studies
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55 Questions14 MinutesCreated by AnalyzingPharm101

Which of the following drugs is also available as Xgeva?

Denosumab (Prolia)

Bazedoxifine and Conjugated Estrogens (Duavee)

Zolendroic Acid (Reclast)

Teriparatide (Forteo)

Which vitamin deficiency would cause Wernicke’s Encephalopathy?

Vitamin B3

Vitamin B1

Vitamin B2

Vitamin C

Which of the following is NOT a rapid acting insulin?

Afrezza

Regular insulin (Humulin R, Novolin R)

Lispro (Humalog)

Aspart (NovoLog)

Which of the following Vitamins is an antioxidant?

Vitamin K

Vitamin C

Vitamin D

Folate

T/F: There are three main types of diabetes. Type 1, Type 2 and gestational Diabetes.

True

False

Which of the following Vitamins is NOT part of a typical vitamin regimen you would give to your patient with macular degeneration?

Zinc

Copper

Vitamin A

Vitamin B2

T/F: Vitamin E in high doses can cause false results on lab tests.

True

False

A patient was recently started on levothyroxine. Which of her medications may affect the levothyroxine dosage requirements?

Vitamin D

Hydrochlorothiazide

Lovastatin

Metoprolol

Which of the following is NOT a non-pharmacologic therapy for osteoporosis?

Smoking Cessation

Exercise

Reducing physical hazards at home

Increase caffeine intake

Your 80 y/o female patient is newly diagnosed with osteoporosis. She has history of CVA in the past and therefore, has residual weakness on the right side of her body, making it hard for her to sit up for more than 15 minutes at a time. Which drug would be the "first line" choice for you to start this patient on?

Denosumab (Prolia)

Alendronate (Fosamax)

Raloxifene (Evista)

Teriparatide (Forteo)

45 year old male presents to your office with depression and looks very thin. PMH is significant for recent excess alcohol use due to losing his job 2 months ago. After doing a neuro exam, you notice he has decreased muscle strength on his UE and LE, as well as some problems recalling what he had for breakfast. What is she most likely deficient in?

B12

Thiamine

Folate

Vitamin C

Which drug has bioavailability issues between drug manufacturers/brands?

Propylthiouracil (PTU)

Lugol’s Solution

Levothyroxine

Liothyronine (Cytomel)

Which of the following is not true about using Levothyroxine in pregnancy?

During pregnancy hypothyroid patients have an increased requirement for levothyroxine

Most patient’s will need to increase their baseline thyroxine dosage by almost 50%

Levothyroxine dosage should return to pre-pregnancy dose 2-3 days after delivery

An increased requirement for levothyroxine can be detected by TSH measurement

When is PTU specifically given over Methimazole?

During the first trimester of pegnancy

During the second and third trimesters of pregnancy

When the patient has history of severe liver injury

In pediatric patients

Which of the following is not an ADR of Pramlintide acetate (Symlin)?

Nausea

Weight loss

Metallic taste

Hypoglycemia

What is the MOA of PTU and Methimazole?

Inhibit TSH from stimulating the receptor, inhibit the coupling of T4 and T3 with mono and diiodotyrosine

Inhibits peripheral conversion of T4 to T3

Inhibit the peroxidase enzyme system, inhibit the coupling of T4 and T3 with mono and diiodotyrosine and PTU inhibits the peripheral conversion of T4 to T3

Inhibits antithyroid peroxidase antibody, inhibits SH receptor stimulating antibodies and inhibits peripheral conversion of T4 to T3

Which of the following is not a class of oral DM medications?

Monoclonal Antibodies

Meglitinides

SGLT 2 inhibitors

DPP-4 inhibitors

A patient taking a TZD would have to get a regular examination of what?

Hearing exam

Eye exam

Bladder CA screening

Endometrial CA screening

Which of the following drugs has a BBW of Thyroid C-cell tumors?

Semaglutide (Ozempic)

Denosumab (Prolia)

Sitagliptin (Januvia)

Pramlintide acetate (Symilin)

Which of the following is a side effect of meglitinides?

Weight gain

LE Edema

CHF

Osteosarcoma

What drug stimulates the release of short acting insulin from the pancreas?

Pioglitazone (Actos)

Repaglinide (Prandin)

Metformin

Canagliflozin (Invokana)

What drug decreases the rate of liver glucose production, augments glucose uptake by tissues and lowers lipids?

Sitagliptin (Januvia)

Acarbose (Precose)

Pioglitazone (Actos)

Metformin

Contraindications of Niacin include all of the following except?

Gout

Hypothyroid

Liver/gallbaldder disease

What drug increases the incidence of bladder cancer in a patient?

Metformin/Sitagliptin (Janumet)

Colesevelam (Welchol)

Dapagliflozin (Farxiga)

Glimepiride (Amaryl)

What oral anti diabetic medication stimulates beta cells to secrete more insulin and increase receptor sites in the tissue?

Alogliptin/Pioglotazone (Oseni)

Semaglutide (Rybeles)

Empagliflozin (Jardiance)

Glyburide (DiaBeta, Micronase, Glynase)

What is a goal for therapy for a diabetic patient?

Lower BG as low as possible

Decrease insulin resistance

Prevention of hypoglycemia from therapy

Lower A1c to 8.5%

What are the antioxidant vitamins?

A, C, E

A, C, E, K

A, D, E, K

A, D, E

What hypothyroid medication is synthetic T3?

Levothyroxine

PTU

Liothyronine (Cytomel)

Liotrix (Euthyroid, Thyrolar)

What is the black box warning of PTU?

Severe liver injury and acute liver failure

Bladder Cancer

Chronic kidney disease

Gallbladder disease

A 25 year old female patient comes back with her thyroid panel results. Her TSH is low and her free T4 is high. Prior to deciding on a medication for her diagnosis, you should test:

HCG

AST/ALT

CrCl

None of the above

Thiazide diuretics interact with what vitamin because of the risk of hypercalcemia?

Vitamin A

Vitamin B2

Folate

Vitamin D

T/F: 70/30 insulin refers to a mixture of 70% basal insulin and 40% bolus insulin.

True

False

Glossitis, cheilosis, and dermatitis are seen in what vitamin deficiency?

Folate

Vitamin B2

Vitamin B1

Vitamin B12

Metformin use can lead to a deficiency of what vitamin?

Vitamin A

Vitamin B12

Vitamin C

Vitamin B1

Your patient has a hx of DVT. What osteoporosis drug would be contraindicated?

Zolendronic Acid (Reclast)

Raloxifene (Evista)

Calcitonin

Alendronate (Fosamax)

How long is the half-life of bisphosphonates?

1 year

Up to 5 years

12 years

Up to 10 years

When is Vitamin A contraindicated? Why?

High doses in pregnancy, can cause fetal harm

Renal disease, toxicity with too much deposited in adipose

Osteoporosis, bone thinning

These are all contraindications

____ is contraindicated in patients with creatinine clearance of < 30 mL/minute.

Raloxifene (Evista)

Calcitonin

Teriparatide (Forteo)

Zolendronic acid (Reclast)

What vitamin can be an adjunctive treatment of HLD?

Vitamin B6

Vitamin E

Vitamin B3

Vitamin B2

What osteoporosis drug has a 28-day convenience pack to take with Calcium?

Ibandronate (Boniva)

Alendronate (Fosamax)

Calcitonin

Risendronate (Actonel)

What are the most common osteoporotic fractures?

Colle's fracture

Vertebrae fracture

Hip fracture

Femur fracture

A 56 yo male presents to your office with complaints of muscle weakness over the last several weeks. He also reports feelings of depression, confusion and memory loss and confirms a history of chronic alcohol abuse. On his neurological exam you note nystagmus, ataxia, and diminished DTRs and sensation. You are concerned for a deficiency and would like to start supplementing?

Vitamin B1

Vitamin A

Folate

Vitamin C

What osteo drug is also treatment for multiple myeloma?

Zometa

Xgeva

Alendronate (Fosamax)

Bazedoxifene and Conjugated estrogens (Duavee)

All of the following insulins are peakless EXCEPT:

Glargine U-300 (Toujeo)

Degludec (Tresiba)

Glargine (Lantus)

Detemir (Levemir)*

56 year old female comes in to your office after being on a medication you prescribed her for osteoporosis. She states she is experiencing the same symptoms she felt when she was pre-menopausal such as hot flashes. She also thinks she might be sick with the flu, but isn't sure. What medication did you most likely prescribe her?

Denosumab (Prolia)

Alendronate (Fosamax)

Raloxifene (Evista)

Duavee

For the patient in question #45, what is an important question you'd want to ask her in PROS when evaluating her?

Have you developed any rashes?

Have you noticed any nose bleeds?

Have you had any leg cramps or traveled for long periods of time?

Have you noticed any back pain with the flu-like symptoms?

Which of these is NOT a vitamin D analogue?

Cholecalciferol

Ergocalciferol

Hydroxycalciferol

Calcitriol

Which of the following is most appropriate for a patient with newly diagnosed hyperthyroidism in the first trimester of pregnancy?

Methimazole

PTU

Radioactive Iodine

Metoprolol

What might be an indication that a patient should be on a levothyroxine dose lower than the standard 1.6micrograms/kg/day?

Elderly

Pregnancy

Cretinism (congenital hypothyroidism)

All of these are indications for lowered levothyroxine dosage

KD is a 69 yo male with T2DM and cirrhosis. Which of the following diabetes medications is contraindicated in this patient?

Glipizide

Lispro

Sitagliptin

Acarbose

MC is a patient with T2DM currently being treated with insulin detemir. You (the PA) determines that MC needs additional insulin therapy for control of postprandial glucose. Which agent is most appropriate to add at this time?

Insulin glargine (Lantus)

NPH insulin (Humulin N, Novolin N)

Insulin aspart (Novolog)

NPH/regular 70/30 insulin

Which class of oral diabetes medications is paired most appropriately with its MOA?

SGLT2 inhibitor- increases urinary excretion of glucose

DPP-4 inhibitor- inhibits breakdown of complex carbohydrates

Sulfonylurea- increases insulin sensitivity

Thiazolidinedione (TZDs)- decreases hepatic gluconeogenesis

Which osteoporosis medication works by preferentially stimulating activity of osteoblasts?

Denosumab

Ibandronate

Raloxifene

Teriparatide

A 55 yo woman with postmenopausal osteoporosis has a PMHx of EtOH abuse, alcoholic liver disease, erosive esophagitis, and hypothyroidism. Which is the primary reason oral bisphosphonates should be used with caution in this patient?

Age

Erosive esophagitis

Thyroid disease

Liver disease

A 50 year old man with HLD, HTN, morbid obesity, type II DM and HF with reduced EF presents to the ED with severe and persistent abdominal pain that radiates to his back. He is afebrile. His lipase level is elevated. Which of the following of his medications is the most likely cause?

Chlorpropamide

Nateglinide

Exenatide

Insulin Glargine

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