Blood and bone marrow

Blood and Bone Marrow Quiz

Test your knowledge on blood and bone marrow with this comprehensive quiz! Covering topics from hemopoiesis to leukocyte functions, this quiz is designed for students, educators, and anyone interested in the fascinating world of hematology.

Key Features:

34 detailed questions
Multiple choice and checkbox formats
Explore various aspects of blood cell formation and function

34 Questions8 MinutesCreated by LearningCell32

Hemopoiesis

Process of production of blood cells

Takes place in red bone marrow

Involves proliferation, differentiation and maturation of cells

All blood cells arise from a single hematopoietic stem cell

Hematopoietic stem cells are found in the thymus

During granulopoiesis, spesific granules are synthesized in myelocytes

Erythrocytes

Cannot leave the blood vessels by diapedesis

Transports oxygen and carbon dioxide

Are unnucleated

Lysosomes are present in their cytoplasm

Human erythrocytes survive in circulation for about 120 days

They have a biconcave shape

Reticulocytes constitute about 1% of all circulating erythrocytes

Leukocytes

Are divided into granulocytes and agranulocytes

Neutrophils are active phagocytes of bacteria

Specific granules of eosinophils contains major basic protein

Basophils has receptors for IgE in their plasmalemma

Neutrophils are less numerous than eosinophils

When activated lymphocytes B proliferate to produce plasma cells and memory cells

Specific granules are more abundant granules in neutrophils

Neutrophils

Has a multilobed nucleus

Contains specific granules

Their tertiary granules contains glycoproteins that are dedicated for insertion into the cell membrane

Their main function is phagocytosis and destruction of bacteria

Erythropoiesis

Is stimulated by EPO

Pro-erythroblasts are precursors of erythrocytes

Reticulocytes has a nucleus

Reticulocytes are filled with hemoglobin

Reticulocytes contain residual ribosomal RNA

True about stem cells and differentiation

Differentiation is not he same as proliferation

Differentiation can occur postnatally

Stem cells can not be recognized according to morphological features

Precursor cells does not leave the bone marrow in normal conditions

Mature cells leave the bone marrow

The amount of yellow bone marrow decreases with age

Red bone marrow features

Sinusoids; sinusoidal capillaries are present

Clusters of developing blood cells are visible

Reticular fibers are present

Color is due to the presence of adipose cells

Contains hematopoietic cords

Lymphocytes

B-lymphocytes can produce immunoglobulins

Makes up approximately 20-40% of all leukocytes

All lymphocytes originate in the bone marrow

All lymphocytes mature in the bone marrow

Has a one-lobed nucleus

B-lymphocytes produces antibodies

There are both B and T-lymphocytes

T-lymphocytes matures in the bone marrow

Their progenitor cells originates in the bone marrow

Hemopoiesis

The process of producing blood cells

Takes place in the yellow blood marrow

Involves proliferation and differentiation of cells

All blood cells arise from a single hematopoietic stem cell

Myelocytes synthesize specific granules during granulopoiesis

Basophils

Belongs to agranulocytes

Contains specific granules

Are the most numerous of the white blood cells

Contains heparin and histamine in their granules

Has IgE receptors on their surface

Are the least numerous of the white blood cells

Thrombocytes

Also reffered to as platelets

Derives from large polyploid cells called megakaryocytes

Main function is clotting of blood

Has a nucleus and well developed organelles

True about hemopoiesis

Hemopoiesis depends on a microenvironment with specific endocrine, paracrine and juxtacrine factors

Red blood cells develop from myeloid cells

Hemopoietic growth factors promote cell differentiation and maturation within specific lineages

Granulocytes develops from myeloid cells

During granulopoiesis, specific granules are synthesized in myelocytes

Hematopoietic stem cells

Are able to respond to growth factor stimulation

Are unable to self-renew

Has a morphology similar to lymphocytes

Megakariocytes

Has a polyploid nucleus

Are the largest of the hematopoietic stem cells

Circulates in blood

Belongs to granulocyte lineage

True regarding blood

Red blood cells has a lifespan of 14 days

Erythrocytes often leaves the circulatory system and migrate to tissues

Reticulocytes are not fully mature erythrocytes

Agranulocytes does not have any granules in their cytoplasm

The membrane of normal erythrocytes has a high flexibility

Leukocytes can migrate into tissues

Matched blood cells and their features

Eosinophils - increase in number during parasitic infection

Eosinophils - has a multilobed nucleus; 8-10 lobes

B lymphocytes - matures in the thymus

T lymphocytes - matures in the thymus

Monocytes - secretes antibodies

Monocytes - macrophages

Statements regarding blood

Plasma contains fibrinogen

Serum contains fibrinogen

Reticulocytes are not fully mature erythrocytes

Serum is devoid of clotting factors

Lymphocytes constitute 4-8% of all circulating leukocytes

Megakaryocytes

Statements regarding erythrocytes

Transports oxygen and carbon dioxide

Are also called white blood cells

Are also called red blood cells

Can leave blood vessels by diapedesis

Statements regarding the bone marrow

A great number of adipose cells are present in the yellow bone marrow

Red bone marrow is present in flat bones and vertebrae

Red bone marrow is a place of maturation of T-cells

Red bone marrow is not hematogenous

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