Part 2 Immunology(50-99) prof. Keit Vanseth

A detailed illustration of the human immune system, highlighting antibodies, T-cells, and other immune responses, with vibrant colors and labeled diagrams.

Immunology Quiz Challenge

Test your knowledge on immunology with this comprehensive quiz designed for students and professionals alike. Dive deep into topics such as antibodies, cytokines, and the immune response. Challenge yourself and discover how well you understand this essential field of study!

50 multiple-choice questions
Covers a wide range of immunological topics
Perfect for revision and self-assessment

50 Questions12 MinutesCreated by LearningLymphocyte482

50. The major role of the complement C3b is to work in conjunction with:

σ� Antibodies to lyse cells antgen

σ� MHC for cell recognition

σ� Antibodies to opsonize cells

σ� T-cell for production of lymphokines

51. All of the following are true for IgE molecules, EXCEPT:

σ� They involved in allergic reactions.

σ� They anti-parasitic immune responses.

σ� They can fix complement.

σ� They can cause the release of histamine.

52. Which of the following immunoglobulin can across placenta with the highest concentration?:

σ� IgG1

σ� IgG2

σ� IgG3

σ� IgG4

53. All of the following are true about antibodies, EXCEPT:

σ� They fix complement.

σ� They occur on the surface of B-lymphocyte

σ� They are glycoproteins.

σ� They are polypeptide

54. In the complement system, the lytic pathway initiated by the complement :

σ� C1qrs

σ� MBL

σ� C4

σ� C5

55. All of the following are true, EXCEPT:

σ� An epitope is a portion of an antigen

σ� The variable contain the antigen recognition site

σ� IgM antibody is pentamer

σ� IgG antibody is pentavalent

56. Which immunoglobulin is the principal one that is unkown function:

σ� IgG

σ� IgM

σ� IgA

σ� IgD

57. Individuals make up over C4a would be expected to have:

σ� Diabetis

σ� Anaphylaxia

σ� Liver disease

σ� Bacteria

58. The immunoglobulin class which is the second abundant in the normal adult is:

σ� IgG

σ� IgA

σ� IgD

σ� IgE.

59. In the alternative pathway of the complement system, the factors below are useful to stabilise the generation of C3 convertase :

σ� Factor P

σ� Factor F

σ� C3-BP

σ� C1-INH

60. The factor that dissociated the initiation of C1qrs in the classical pathway is:

σ� C3-BP

σ� Factor F

σ� Factor P

σ� C1-INH

61. The type of an immunoglobulin is determined by:

σ� The variable region

σ� The light chain

σ� The heavy chain

σ� The carbohydrate

62. Each of the following is a characteristic of antibodies, EXCEPT :

σ� They are proteins with variable and constant regions

σ� They contain carbohydrates

σ� They are only secreted by T-cells

σ� They combine specifically with antigen

63. The T3 complex of the T-cell receptor:

σ� To transduce a signal to the cell's interior

σ� Binds complement

σ� Causes the histamine

σ� Mediates Immunoglobulin class switching

64. Which of the following is NOT true of interleukins?:

σ� Produced by cells of the immune system.

σ� Relation between cells of immune system

σ� They have receptors on the target cell.

σ� They bind antigen with a high specificity.

65. The following statements are true for IgE, EXCEPT:

σ� They produce allergic reaction

σ� The least immunoglobulin in the plasma

σ� They bind to mast cells

σ� Can cross the placental barrier

67. The following statements are true, EXCEPT:

σ� IgM and IgG can fix complement

σ� IgA is a secretory immunoglobulin

σ� IgE mediates hypersensitivity

σ� IgD provides passive immunity

68. The following statements are true for Antibodies, EXCEPT:

σ� Non immunogen

σ� Composed of variable and constant regions

σ� Made of heavy and light chains

σ� They have hypervariable region

69. The following statements are not true for Immunoglobins

σ� They have Fab

σ� Five major classes of immunoglobulin

σ� All have receptors for complement

σ� Possess both variable and constant regions

70. The following statements are true for Antibodies

σ� Are carbohydrates

σ� Are made from alpha and beta chains

σ� Contain cytoplasmic region

σ� Have variable region

71. The Biological Effects of C3b is :

σ� Susceptibility to bacterial infections

σ� Anaphylaxia

σ� Phagocyte activation

σ� Lack of opsonisation

72. The following statement is for MHC Class I:

σ� Recognized by the CD8 protein

σ� Used to kill by cytotoxic T-cells

σ� Participated in helper function

σ� Not able to carry an antigen fragment

73. The major histocompatibility complex proteins function to:

σ� Degrade T4 and T8 polypeptides

σ� Bind antibody for lymphokine production

σ� Bind complement for cell lysis

σ� Bind antigen for presentation to T-cells

74. Variable domains are:

σ� Needed to bind complement

σ� Located at the N-terminal of heavy chains

σ� Transported IgG across the placenta

σ� Specific recognition of antigen

75. The light chains of antibodies are distinguished by:

σ� Their constant specific region

σ� Their variable region domains

σ� Kappa or lambda types

σ� The J-chains that bind to them

76. Which of these cell types can play a primary role in attacking and killing cancer cells?:

σ� Platelet

σ� Cytotoxic

σ� T cell

77. The J-chain is :

σ� Made only by epithelial cells

σ� For immunoglobulin multimer formation

σ� For immunoglobulin multimer formation and Facilitates secretion of pentameric lgM

σ� Facilitates secretion of pentameric lgM

78. The functional activity of the T-cell:

σ� Is related with CD4 or CD8 associated polypeptides

σ� Occurs after recognition of an epitope

σ� Can be mediated through cytokines

σ� All answers

79. The followings statement are FALSE for Target cell lysis and destruction :

σ� Tc recognizing specific epitopes

σ� Perforin released from Tc

σ� C3b fix to IgG and IgM which have epitopes

σ� C3b fix to IgE which have epitopes

80. The followings statement are TRUE, EXCEPT:

σ� MHC I bind antigen and recognized by the Tc

σ� MHC I presented on all cells of the immune

σ� MHC II bind antigen and recognized by the Th

σ� MHC II carrying antigen presented to Tc

81. What distinguishes helper T-cells from cytotoxic T-cells:

σ� Th recognize antigen with MHC I

σ� Tc recognize antigen with MHC I

σ� Th recognize antigen with MHC II

σ� Tc recognize antigen with MHC I and Th recognize antigen with MHC II

82. Clinical abnormalities of the Immune system can result from the following statement, EXCEPT:

σ� Deficiency diseases

σ� Abnormal lymphocyte proliferation

σ� HIV Infection

σ� T cells proliferation

83. Which of the following represent immune system dysfunctions:

σ� Severe immunodeficiency

σ� Mast cells release histamine

σ� Facilitated by antibodies

σ� T cells proliferation

84. The following statement are for adaptive immune response, EXCEPT :

σ� Is mediated by the humoral and cellular of the immune

σ� Can be facilitated by antibodies

σ� Can be facilitated through T-cells

σ� Can be facilitated through macrophage cells

85. Which of the followings are NOT TRUE regarding an immune response:

σ� The principal function of the T3 complex is signal transduction to the cell's interior

σ� The T8 serves an auxiliary role with MHC class I proteins in cytotoxic reactions

σ� The T4 serves an auxiliary role with MHC class II proteins in helper cell reactions

σ� Lymphokines are produced by T-cells in response to antigen presentation by antibody

86. Skin is a________ barrier:

σ� Anatomical

σ� Physiological

σ� Phagocytic

σ� Inflammatory

87. Which among the following is anti-bacterial ?:

σ� Interferon

σ� Lysozyme

σ� Hormone

σ� Protein

89. Histamine is secreted by:

σ� Epithelial cell

σ� Mast cells

σ� Red blood cells

σ� White blood cells

90. Humoral immunity consists of:

σ� Normal cells

σ� Pathological cells

σ� Cytotoxic cells

σ� Immunoglobulins

91. Complement deficiencies of C3b can cause:

σ� Overproduction of C2b

σ� Glucose oxidase deficiency

σ� Predisposition to SLE

σ� Bacterial infection

95. Hyper variability regions are present in:

σ� Heavy chain only

σ� Light chain only

σ� Heavy and light

σ� Dark chain

96. Organ transplantation of human from one place to another is called:

σ� Autograft

σ� Allo-graft

σ� ISO-graft

σ� Xeno-graft

97. Graft between identical twins is called:

σ� Xeno-graft

σ� Allograft

σ� Auto graft

σ� Iso graft

98. What is the term used to describe white blood cells migrating toward bacteria? :

σ� Zeiosis

σ� Phagocytosis

σ� Chemotaxis

σ� Phototaxis

99. Name the process a cell such as a neutrophil or a macrophage uses to ingest (eat) its prey.:

σ� Halitosis

σ� Chemotaxis

σ� Botulism

σ� Phagocytosis

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Part 2 Immunology(50-99) prof. Keit Vanseth

Immunology Quiz Challenge

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