HEMA LEC WEEK 2
Examine Your Knowledge of Hemolytic Disorders
Test your understanding of Hemolytic Disorders and their clinical implications with this comprehensive quiz designed for medical students and healthcare professionals. Dive into key topics such as Paroxysmal Cold Hemoglobinuria, Hemolytic Disease of the Newborn, and the associated laboratory findings.
Whether you are looking to brush up on your knowledge or prepare for an upcoming exam, this quiz will help reinforce your learning.
- 10 challenging multiple-choice questions
- Instant feedback on your answers
- Improve your clinical knowledge and diagnostic skills
A vasospastic disorder causing discoloration of the fingers, toes and occassionally other extremities
Raynaud's phenomenon
Sjogren syndrome
Systemic sclerosis
Raynaud's disease
The following statements are true about Paroxysmal Cold Hemoglobinuria:
Caused by binding of the Donath-Landsteiner Ab to the patient's RBC
Occurs following exposure to cold temperature
Autoantibody is IgG
All of the above
What does a positive Coomb's test mean?
Presence of autoantigen
Presence of superantibodies
Presence of antibodies directed against other people's RBC
Presence of antibodies directed to own RBC antigens
Clinical presentation of Hemolytic disease of the newborn except:
Jaundice
Anemia
Kernicterus
Diarrhea
The following statements are true regarding alpha-methyldopa mechanism
IAT negative
Drug interact with RBC and induces the release of immunogenic epitopes that elicit an immune response
DAT negative for Anti-C3
None of the above
Immediate type of Hemolytic Disease of the Newborn causes Intravascular Hemolysis
True
False
The following are laboratory findings in Hemolytic Disease of the Newborn (HDN) except:
Macrocytic anemia
Hyperbilirubinemia
Leukocytopenia
Leukocytosis
Delayed type of Hemolytic Disease of the Newborn causes Extravascular Hemolysis
True
False
Paroxysmal Cold Hemoglobinuria DAT result
Anti-C3 positive, Anti-IgG positive
Anti-C3 positive, Anti-IgG negative
Anti-C3 negative, Anti-IgG negative
Anti-C3 negative, Anti-IgG positive
Serologic test used to detect the presence of a biphasic hemolysin and used to diagnose Paroxysmal cold hemoglobinuria
Donath-Lansteiner test (DL)
Direct Antiglobulin test (DAT)
Indirect Antiglobulin test (IAT)
PCR
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